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Research ArticleOpen accessIn the abstractTHE EFFECT OF DIABETES MELLITUS ON THE CLINICAL AND MICRO-BIOLOGICAL OUTCOMES IN PATIENTS WITH ACUTE PYELONEPHRITISKathleen Lynch, Veena Venugopalan, Levita HidayatThere is some published evidence which suggests that the clinical outcomes and pathogens associated with Acute Pyelonephritis (AP) differ between diabetics and non-diabetics. However, current guidelines do not make treatment distinctions based on Diabetes Mellitus (DM) status. The objectives of this study were to identify the microbiological and clinical characteristics of hospitalized patients with AP and investigate differences between patients … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 6 May 2014 · 7,378 accessesView PDF Cite

Research ArticleOpen accessIn the abstractASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,076 accessesView PDF Cite

Research ArticleOpen accessIn the abstractClinical and Sociodemographic Risk Factors for Tuberculosis in Human Immunodeficiency Virus Infected PatientsPaz-Ayar Nibardo, Jose Antonio Mata-Marin, Jesus Gaytan-Martinez et al.To identify clinical and sociodemographic factors associated with the risk of tuberculosis in HIV-infected patients. A case-control study in a cohort of HIV-infected patients. Cases: patients coinfected with HIV and pulmonary or extrapulmonary tuberculosis. Controls: no clinical tuberculosis and PPD negative, matched for age and sex. Primary data were obtained from medical records and personal interviews. We identified 47 cases … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 30 Nov 2013 · 8,239 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffect of Leptospirosis on the Concentrations of Streptomycin in Liver and Kidneys of PigsLabrini V. Athanasiou, Vassilios Papatsiros, George Valiakos et al.Leptospirosis is a re-emerging infectious disease with zoonotic potential. Pigs are reservoir hosts of the pathogen and streptomycin is among the antibiotics proposed to eliminate leptospiral infection. The purpose of this study was to determine streptomycin concentrations and the possible effect of the presence of Leptospira in the liver and kidneys on drug distribution. Six pigs with leptospirosis and six … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 28 Mar 2013 · 7,488 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAssociation of Mycoplasma pneumoniae Infection With Ischemic Heart DiseasesAbdullah S. Assiri, Adil H. Alshehri, Osama M.S. Abdul-Wahab et al.Association of atherosclerosis and coronary artery disease well known main pathophysiologic basis for Ischemic Heart Diseases and Myocardial Infarction and due to major risk factors such as high plasma level of low density lipoprotein, low plasma level of high density lipoprotein, cigarette smoking, hypertension and diabetes mellitus, infection with few infectious agents such as Mycoplasma pneumoniae that might associated with … …American Journal of Immunology, Vol. 8, Issue 4 · 11 Oct 2012 · 8,096 accessesView PDF Cite

Research ArticleOpen accessIn the abstractImmunodeficiency Provides Partial Protection from Bone Loss Induced by Castration and OvariectomyCedo M. Bagi, Edwin Berryman, Nels Hanson et al.Problem Statement: The interaction of osteoblasts and osteoclasts with cells of the immune system has been suggested as a contributing factor in the development of osteoporoses. Evidence from studies in rodents suggests that T cells play a significant role in bone loss following estrogen deficiency. The goal of this study was to investigate whether the lack of functional T cells … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,075 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMortality among HIV-Infected Patients in Resource Limited Settings: A Case Controlled Analysis of Inpatients at a Community Care CenterNirmala Rajagopalan, Joyce B. Suchitra, Anita Shet et al.Problem statement: Despite massive national efforts to scale up Antiretroviral Therapy (ART) access in India since 2004, the AIDS death rate was 17.2 per 100,000 persons during 2003-2005. In the era of HAART in resource poor settings, it is imperative to understand and address the causes of AIDS related mortality. This collaborative study aimed at defining the predictors of mortality … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,664 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Pathology of Alzheimer Disease Elicits an In Vivo Immunological ResponseDavid J. Bonda, Kate M. Webber, Sandra L. Siedlak et al.The mechanism(s) responsible for the loss of neurons that characterizes Alzheimer disease is incompletely understood. Nonetheless, there is considerable evidence suggestive of immune abnormalities coupled to alterations in blood-brain barrier permeability that likely play a key role in both the etiology and progression of the disease. To examine these issues further, this study was designed to examine the presence of … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,118 accessesView PDF Cite