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38 articles for “low doses”
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Research ArticleOpen accessIn the abstractAntidepressant-Like Activity of Banana Peel Extract in MiceTan Pei Tee, Halijah HassanProblem statement: Depressed mood, loss of interest or pleasure, feeling guilty, low selfesteem, sleep disturbance, loss of appetite, low energy and poor concentration are the characteristics of depression. This common mental disorder can occur in anyone regardless of genders, ages and backgrounds. People counteract it with psychotherapy and medications. Alternatively, some patients use herbal remedies as treatments. Recently, natural herbal … …Current Research in Medicine, Vol. 2, Issue 2 · 1 Oct 2011 · 18,671 accessesView PDFCite
Research ArticleOpen accessIn the abstractPorcine Brain Extract Attenuates Memory Impairments Induced by Focal Cerebral IschemiaJinatta Jittiwat, Jintanaporn Wattanathorn, Terdthai Tongun et al.Problem statement: Stroke or cerebral ischemia has been recognized as one important problem worldwide. To date, the effectiveness of protective and therapeutic strategies against stroke is still very limited. Therefore, the development of novel strategy is required. Porcine brain is traditional believed to improve brain functions. Recent studies showed that the extract of porcine brain could protect against brain damage … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 14,615 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Intravenous Ketamine Administration on Blood Glucose Levels in Conscious RabbitsSuleiman I. Sharif, Hanan A. AbouazraProblem statement: The intravenous general anaesthetic ketamine has been shown to produce changes in blood glucose levels. It is important to study the pharmacological basis of such an effect. Approach: The influence of varying doses of ketamine administered intravenously was studied in conscious rabbits. Serum glucose was determined by blood glucose method using an enzymatic PAP250 kit. Results: Low doses … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 2 · 30 Jun 2009 · 9,945 accessesView PDFCite
Research ArticleOpen accessIn the abstractBehavioral, Physiological and Biochemical Hormetic Responses to the Autoxidizable Dye Methylene BlueAleksandra K. Bruchey, F. Gonzalez-LimaThe goals of this review were to identify methylene blue (MB) as a compound that follows hormetic behavior for a wide range of effects and to address the question of what is unique about MB that could account for its wide applicability and hormetic behavior as a drug. The MB hormetic doseresponse relationship is exemplified by an increase in various … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 15,044 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical and Immunological Study on the Effects of Barley and its Components as Hypoglycemic Agents in Diabetic RatsMokhtar I. Yousef, Medhat Haroun, Mohamed H. El-Masry, Reham EA. AteiaThe present study was carried out to investigate the hypoglycemic effect of barley (Hordeum vulgare L) and some of its components such as amino acids (L-leucine and L-glutamine) and chromium picolinate on some biochemical and immunological parameters of alloxan induced diabetic rats. Alloxan-diabetic rats were treated with barley water (10% w/v) at a dose 10 ml Kg-1 b.wt., chromium picolinate … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 1 · 31 Mar 2006 · 7,233 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioanalytical Method Validation and Quantification of Flupirtine in Canine Plasma by HPLC with Spectrofluorimetric DetectionVirginia De Vito, Alessandro Saba, Helen Owen, Mario GiorgiFlupirtine (FLU) is a non-opioid analgesic drug belongs to the class of N-Methyl-D-Aspartate (NMDA) antagonist without antipyretic or antiphlogistic properties. No analytical method to detect FLU in canine plasma samples through a fluorimetric detector has been published to date. The analytical method described in this work provides a selective and accurate quantification of FLU. The mobile phase consisted of ACN:AcONH4 … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 22 Jun 2015 · 7,982 accessesView PDFCite
Research ArticleOpen accessIn the abstractPolyherbal EMSA ERITIN Blocks Nuclear Factor-Kappa B (NF-κB) and Proinflammatory Cytokines in Irradiated MiceYuyun Ika Christina, Mansur Ibrahim, Muhaimin Rifa’iRadiation therapy is commonly used in cancer treatment that produce deleterious effects, such as normal cell death (apoptotic or necrotic) and suppression of hematopoietic stem cells. This effect was caused by ion rays that can rise to high of free radical. The high of free radical trigger the inflammation of cells. EMSA ERITIN is medicinal herb used as preventative agents … …American Journal of Immunology, Vol. 11, Issue 1 · 29 May 2015 · 7,518 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa Oleifera Leaves Extract Attenuates Male Sexual DysfunctionWipawee Thukhammee, Supaporn Muchimapura, Sitthichai Iamsa-ard et al.Problem statement: At present, the novel agent that is effective, cheap and easy to approach for treating male sexual dysfunction is required due to the current poor therapeutic efficacy. Though Moringa oleifera is reputed for aphrodisiac activity in traditional folklore, no scientific evidence is available. Therefore, we aimed to determine the effect of M.oleifera leaves extract on male sexual behaviors … …Neuroscience International, Vol. 3, Issue 1 · 1 Sep 2012 · 32,897 accessesView PDFCite
Research ArticleOpen accessIn the abstractCoscinium Fenestratum Protects Against Ethanol-Induced Neurodegeneration in Adult Rat BrainWathita Phachonpai, Jintanaporn Wattanathorn, Panakaporn Wannanon et al.Alcoholism is a serious problem throughout the world. Despite intensive efforts to develop novel therapeutics for strategy efficacy against neuronal loss leading to memory impairment in alcoholism is still limited. In view of the pitfalls of psychological dependence and adverse behavioral effects of synthetic drugs, the development of low toxicity and high efficiency medicines derived from natural herbal antioxidants exhibits … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 16 Aug 2012 · 8,602 accessesView PDFCite
Research ArticleOpen accessIn the abstractForest Fires and Resuspension of Radionuclides into the AtmosphereFernando P. Carvalho, Joao M. Oliveira, Margarida MaltaProblem statement: Forest fires are especially frequent around the Mediterranean Sea basin in the summer period and might be able to release naturally-occurring and man-made radionuclides from plant biomass and inject them into the atmosphere. The impact of this radioactivity on populations was not investigated before. Approach: Radionuclide analysis was performed in plants, in smoke from plant burning and in … …American Journal of Environmental Sciences, Vol. 8, Issue 1 · 14 Jan 2012 · 7,352 accessesView PDFCite