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91 articles for “inhibitors”
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Research ArticleOpen accessIn the keywordsAccumulation of Cholesterol Esters in ex vivo Lymphocytes from Scrapie-susceptible Sheep and in Scrapie-infected Mouse Neuroblastoma Cell LinesAlessandra Pani, Claudia Norfo, Claudia Abete et al.Our studies on the role of cholesterol homeostasis in the pathogenesis of scrapie in sheep, revealed abnormal accumulation of cholesterol esters in brains and in ex vivo skin fibroblasts from genetically scrapie-susceptible, as compared to sheep with resistant genotype. We now report that PBMCs isolated from scrapie-susceptible sheep, as well as mouse neuroblastoma cell lines persistently infected with two different … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,960 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffects of Steam Conditioning and Extrusion Temperature on Some Anti-nutritional Factors of Soyabean (Glycine max) for Pet Food ApplicationsB. Purushotham, P.M. Radhakrishna, B.S. SherigaraExtrusion processing of vegetable ingredients such as soyabean (Glycine max) characteristically depends on associating process conditions that influence the product qualities. The process parameters were optimized for extrusion of steam-conditioned material in order to obtain the maximum nutritive value by inactivating the anti-nutritional factors such as urease, trypsin inhibitors and lipase. The processing conditions such as moisture content, temperature and … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 1 · 31 Jul 2007 · 9,030 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSevere and Fatal Influenza Cases in Russia in 2014-2015Svetlana V. Svyatchenko, Alexander G. Durymanov, Ivan M. Susloparov et al.This paper aims to characterize herd immunity of the population inhabiting Asian part of Russia before influenza epidemic and to describe influenza viruses isolated from severe cases including cases with fatal outcomes in the 2014-2015 epidemic season. HI test enabled us to study 3888 serum samples from healthy individuals including 1939 samples collected from poultry farm workers. We showed that … …OnLine Journal of Biological Sciences, Vol. 16, Issue 4 · 24 Dec 2016 · 7,069 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHigh Frequency of Stop Codons in the Human Immunodeficiency Virus-1 Protease Gene Frame in Human Immunodeficiency Virus+ Individuals with Below Detectable Levels of Plasma Viremia During Highly Active Antiretroviral TherapyMagdalena Czubala, Kabo Matlho, Maria Arriaga et al.We performed sequence analysis of HIV-1 proviral protease gene fragment (560 base pairs) amplified from ex-vivo peripheral blood mononuclear cells of 83 HIV+ individuals with Below Detectable Levels (BDL) (<20-40 RNA copies/ml plasma) and detectable levels of plasma HIV viremia while on HAART. Noteworthy was the systematic presence of stop codons identified only in the BDL group and not in … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 14 Nov 2012 · 8,075 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThermodynamic Characteristics of Camel’s Urine as an Inhibitor for Mild Steel in 1.5 M H2SO4 Acid SolutionEhteram A. Noor, Azza A. Al-Ghamdi, Aisha H. Al-MoubarakiProblem statement: The corrosion inhibition of mild steel in 1.5 M H2SO4 by Camel’s Urine (CU) addition was evaluated at five different temperatures in the range from 30-70°C by weight loss measurements. CU acts as a good inhibitor for the corrosion of mild steel in 1.5 M H2SO4. The value of inhibition efficiency increases with increasing both inhibitor concentration and … …American Journal of Applied Sciences, Vol. 8, Issue 12 · 22 Oct 2011 · 7,373 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCorrelation Between MMP-3, TIMP-3 Expression and Neuronal Apoptosis After Ischemia -Reperfusion Injury in RatesZi Xiaohong, Mutasem Abuhamed, Yuan Yi et al.Matrix metalloproteinases (MMPs) play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis. How MMP3, TIMP3 expression and neuronal apoptosis (Fas, Fas-L and Bcl) may provide detrimental or beneficial actions during the injury and repair processes after cerebral ischemia-reperfusion injury in rates was studied. Adult rats underwent middle cerebral artery occlusion (MCAO) … …American Journal of Immunology, Vol. 3, Issue 2 · 30 Nov 2007 · 7,182 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Characterization and in Silico Analysis of Phytochemical Compounds from Plants with Immunomodulatory PotentialHermin Pancasakti Kusumaningrum, Rejeki Siti Ferniah, Siti Nur Jannah et al.The immune system works to protect the body against foreign antigens from microorganisms and abnormal cells. The use of herbal plants as immunomodulators are used to prevent disease attacks. TNFα and interleukin-6 are pro-inflammatory immune systems that cause disease in uncontrolled synthesis. Herbal plants as inhibitors of TNFα and interleukin-6 need to be identified molecularly to reduce the occurrence of … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 27 Nov 2025 · 1,959 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibitory Effects of Artemisia afra Extracts on the Bio-Activity of Banana TyrosinaseTsholofelo Motshologane, Jacobus Pieter Hough Van WykMelasma, formerly known as chloasma, is an acquired pigmentary condition, occurring most commonly on the face of humans. This disorder, which is more prevalent in females and darker skin types, is predominantly attributed to Ultraviolet (UV) exposure and hormonal influences. This condition is caused by an over-production of melanin, a pigment that gives color to the skin, hair, and eyes … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 18 Jan 2025 · 4,621 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Gliflozin Therapy on TNF-α Secretion by Cultured Monocytes in Patients with DiabetesTatiana Vladimirovna Kirichenko, Leyla Azimovna Bochkareva et al.Currently it’s well established that chronic inflammation is a key pathogenetic mechanism in the development of Type 2 diabetes. The study aims to explore the inflammatory response of monocytes in diabetic patients compared to healthy subjects, focusing on TNF-α and to investigate the impact of SGLT2 inhibitors on monocyte inflammation. The study included 20 patients with newly diagnosed type 2 … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 4,825 accessesView PDFCite
Review ArticleOpen accessIn the abstractTransformation of Lignocellulosic Biomass into Sustainable Biofuels: Major Challenges and Bioprocessing TechnologiesTahira Naz, Yusuf Nazir, Abu Bakr Ahmad Fazili et al.Commercial-scale production of biofuels has recently been intensified due to its cost-effectiveness, sustainability, market stability, alternative fuel energy composition and greener output, etc. Lignocellulosic biomass attracted the attention of researchers as a renewable feedstock for fermentative conversion into biofuels because of its high productivity, low agricultural input requirements, being environmentally friendly and no competition with the food crops. The field … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 4 · 1 Aug 2020 · 7,713 accessesView PDFCite