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54 articles for “immunomodulator”
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Research ArticleOpen accessIn the keywordsInduction of a Soluble Anti-HIV-1 factor (s) with IFN-γ, IL-10, and β-Chemokine Modulating Activity by an Influenza-Bacterial Polyantigenic MixtureJosé W. Rodríguez, Nat O. Pagan, Mar C. Ocasio et al.Partial immune restoration may be obtained with highly active antiretroviral therapy (HAART), but specific anti-HIV-1 immune responses do not appear to improve substantially. We have demonstrated that a soluble factor(s) induced by a mixture of inactivated influenza and bacterial vaccines called polyantigenic immunomodulator (PAI), possesses strong immunoregulatory and anti- HIV-1 activities. In the present study, we show that culture fluids … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,845 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPharmacological Properties of Bioactive Extracts from the Rhizome of Aristolochia longa LAmal El Hamsas El Youbi, Dalila BoustaAristolochia longa is a medicinal plant well known in Moroccan folk medicine for its activity against constipation, intestinal infections and skin diseases. The present study was performed to evaluate in vitro and in vivo immunomodulatory and cytotoxic activities of aqueous and protein extracts of A. longa. The in vitro immunomodulatory results showed that aqueous extract at 0.1 mg/mL enhanced T-lymphocyte … …American Journal of Pharmacology and Toxicology, Vol. 15, Issue 1 · 21 Jul 2020 · 7,456 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Bioactivity of Fucoxanthin from Undaria pinnatifida in VitroYiting Li, Ye Liu, Yuepeng Wang et al.Fucoxanthin, a marine carotenoid, can be found in marine algae and some marine invertebrates, has remarkable biological properties for human health. It is known that fucoxanthin has anti-cancer activity on some human cancer cells such as human colon cancers, leukemia cells, prostate cancer cells, breast cancer cells. In this study, the fucoxanthin was extracted from Undaria pinnatifida, after purification by … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 2 · 7 Jun 2016 · 7,866 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPhysiological Active Substance Changes of Soybean Curd Residue Fermented by Preussia aemulans and its BioactivityYiting Li, Shili Meng, Min Shi, Zhenya ZhangA new species of fungus Preussia aemulans isolated from the Cordyceps sinensis fruiting body was cultured by soybean curd residue using solid-state fermentation method. The content of polysaccharide, amino acid, protein, phenolics and nucleoside were massively improved under the optimum conditions, including 10% adding dosage of glucose, 3% adding dosage of beef extract, 15 days of fermentation time. The crude … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 1 · 6 Jan 2016 · 7,453 accessesView PDFCite
Research ArticleOpen accessIn the keywordsImmune-Based Therapies for Spinal Cord InjuryBasem I. Awad, Davina V. Gutierrez, Michael P. SteinmetzTraumatic Spinal Cord Injury (SCI) results in both focal and diffuse spinal cord pathologies that are exacerbated by an inflammatory response after the initial injury. Resident and infiltrating immune cells contribute significantly to the growth-refractory environment near the lesion and can intensify damage to spared tissue, resulting in impaired spontaneous functional recovery. Numerous studies have demonstrated that several immunomodulatory therapies … …Neuroscience International, Vol. 4, Issue 1 · 17 Apr 2013 · 6,877 accessesView PDFCite
Research ArticleOpen accessIn the abstractGlucans and the Poultry Immune SystemJacqueline Jacob, Anthony PescatoreWith the reduced availability of antibiotics, poultry producers are looking for feed additives to stimulate the immune system of their birds. Some beta-glucans have been shown to improve gut health in poultry subjected to a bacterial challenge, to increase the flow of new immunocytes into the various lymphoid organs, to increase macrophage function, to increase antibody titers after a vaccination … …American Journal of Immunology, Vol. 13, Issue 1 · 12 Apr 2017 · 12,367 accessesView PDFCite
Review ArticleOpen accessIn the abstractHost Receptor Immunomodulation in Response to Shigella Surface Antigens: An Insight for Vaccine DevelopmentAshim K. Bagchi, Rushita A. Bagchi, Dipak K. Hens et al.Shigellosis, caused by Shigella is the most common cause of bacillary dysentery. The disease is associated with high morbidity and mortality rate owing to its multiple drug resistance. Hence recovery from the disease would primarily depend on the development of an effective immune-modulator for strong mucosal immune response. The role of cellular immunity may be a critical factor in protection … …American Journal of Immunology, Vol. 11, Issue 2 · 21 Jun 2015 · 6,752 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlacebo-Driven Clinical Trials of Transfer Point Glucan #300 in Children with Chronic Respiratory Problems: III. Clinical FindingsVetvicka Vaclav, Richter Josef, Svozil Vladimir et al.The role of glucan in stimulation of immune reactions has been studied for decades. In this report we focused on the effects of orally administered glucan in children with chronic respiratory problems. We measured the physical endurance using a 6MWT test and the levels of eNO in 50 children aged 8-12 years and evaluated the effects of 100 mg/d oral … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 9,028 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlacebo-Driven Clinical Trials of Transfer Point Glucan #300 in Children with Chronic Respiratory Problems: Antibody ProductionVetvicka Vaclav, Richter Josef, Svozil Vladimir et al.The role of glucan in stimulation of immune reactions has been well-established. In this report, we focused on the antibody production in glucan-supplemented children with chronic respiratory problems. We measured the levels of salivary IgA, IgM and IgG in 40 children aged 8-12 years and evaluated the effects of 100 mg d-1 oral dose of glucan. We found a significant … …American Journal of Immunology, Vol. 9, Issue 2 · 5 Jun 2013 · 10,462 accessesView PDFCite
Research ArticleOpen accessIn the abstractUnderstand the Role of Natural KillerHan Yuen Lam, Swee Keong Yeap, Noorjahan Banu Alitheen et al.Problem statement: Immunosuppression is a common approach for pathogens or cancer to escape from immune system of the infected host. Some of the antimicrobe or anticancer drugs may also weaken the body immune system. Among various types of immune cell, natural killer cells are the key component of the innate immunity which plays an important role in first line defense … …American Journal of Immunology, Vol. 6, Issue 4 · 5 Aug 2011 · 7,935 accessesView PDFCite