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66 articles for “immunodeficiency”
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Research ArticleOpen accessEvery word in the titleInnate, Adaptive and Intrinsic Immunity in Human Immunodeficiency Virus InfectionSuneth S. Perera, Nitin K. SaksenaThe first line of defence of the innate immune system functions by recognizing highly conserved sets of molecular structures specific to the microbes, termed pathogen-associated molecular patterns, or PAMPs via the germ line-encoded receptors Pattern-Recognition Receptors (PRRs). In addition to the innate immune system, the vertebrates have also evolved a second line of defence termed adaptive immune system, which uses … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 27 Nov 2012 · 9,723 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEfficacy of an Oral Health-Promoting Program in Human Immunodeficiency Virus-Infected Children: A 7-year Longitudinal StudyNathalia Ferraz Oliscovicz, Gloria Fernanda Barbosa de Araújo Castro, Luciana Pomarico, Ivete Pomarico Ribeiro de SouzaProblem statement: Children infected with HIV have a higher prevalence of caries in both dentitions. With that in mind, it is important the introduction of programmes for the control of caries disease in this population. Thus, this study was aimed to assess the efficacy of an oral health-promoting program in controlling caries in HIV-infected children after 7 years of follow-up. … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 30 Jul 2012 · 7,907 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMicrobial Translocation and B Cell Dysfunction in Human Immunodeficiency Virus DiseaseWei JiangThe gut mucosal barrier disrupted in HIV disease, resulting in increased systemic exposure to microbial products such as Lipo Polys Accharide (LPS). The association of enhanced microbial translocation and B cell dysfunction in HIV disease is not fully understood. High dose and short term exposure of microbial Toll-Like Receptor (TLR) agonists were used as vaccine adjuvants, however, low dose and … …American Journal of Immunology, Vol. 8, Issue 2 · 30 Jun 2012 · 7,409 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFrequency of P/S(XX)P Duplication and FRFE, Absence of LYP in P6Gag of Indian Human Immunodeficiency Virus-1 Subtype C IsolatesKrutika Wadekar, Sudhanshu Pandey, Preeti Jain et al.Problem statement: The presence of a p6 domain at the C-terminus of the Gag polyprotein is a characteristic feature of HIV-1 and other primate lentiviruses. The p6Gag protein is considered as a major phosphoprotein in mature HIV-1 virions and is involved in the viral assembly and budding process. Sequence variation in the p6gag region in HIV-1 has been associated with … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,529 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of Resistance to Human Immunodeficiency Virus Protease Inhibitors Using Molecular Mechanics and Machine Learning StrategiesA. Harishchander, D. Alex Anand, Sanjib SenapatiProblem statement: Drug resistance is the most important factor, which influences the failure of current HIV therapies. So, the ability to predict the drug resistance of HIV-1 protease mutants will be useful in developing more effective and longer lasting treatment regimens. Approach: Drug resistance of HIV-1 protease is predicted with two current protease inhibitors (Indinavir and Saquinavir). The problem was … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,204 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Cross-sectional Study of Sexual Practices, Sexually Transmitted Infections and Human Immunodeficiency Virus among Male-to-Female Transgender PeopleP.S. Saravanamurthy, P. Rajendran, Priya Maria Miranda et al.Problem statement: Designing HIV interventions requires evidence on links between behaviors and elevated transmission risk that remains scanty for male-to-female Transgender (TG) people in India. Approach: In 2007, we carried out a cross-sectional study through convenience sampling of 131 TG aged > 18years, residing in Chennai at least prior to six months of the study. Sexual practices and perception towards … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 8,370 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleZinc Deficiency and Associated T-Cell Dysfunctioning among Human Immunodeficiency Virus SeropositivesM. Andrew Pradeep, M. Thiruvalluvan, V. Nalini, J. Stella MaryProblem statement: All the nutrients in the diet play a crucial role in maintaining an optimal immune response. In both, deficient and excessive intake of nutrients can have negative consequence on the immune status and susceptibility to a variety of pathogens. Zinc is an essential micronutrient for human growth development and immune function. It plays a vital role in structure … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 8,037 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHepatitis B and C Positivity in Various Categories of Human Immunodeficiency Virus Seropositive Individuals in a Regional STD Centre-an Eight-Year Evaluation of Trends and Risk FactorsSumathi Muralidhar, Manju Bala, Rakesh Kumar Jain et al.Problem statement: Among the various infections whose incidence has increased since the advent of HIV/AIDS, Hepatitis B and C stand out clearly. This is so because the routes of transmission of these infections are essentially the same as those of HIV/AIDS, making co-infections a common occurrence. The risk of infection for Hepatitis B and C is several times more than … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 6,925 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRole of Hematological and Alternate Markers in Human Immunodeficiency Virus Disease ProgressionK. V. Ramana, Jagadeeshwara Chary, V. Sabitha et al.Problem statement: The knowledge of HIV infection has expanded tremendously which has led to significant improvement in the treatment, leading to decrease in morbidity and mortality. Considering the limitations in using CD4+T-cell counts and HIV RNA viral load as markers in the HIV disease progression, physicians treating the HIV patients now look for alternate markers that predict HIV disease progression … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,372 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Study on Erythrocytic Determination of Anemic Condition among Human Immunodeficiency Virus Sero PositivesM. Andrew Pradeep, M. Thiruvalluvan, V. DhamodharanProblem statement: Acquired Immuno Deficiency Syndrome (AIDS) is growing health hazard throughout the world. In developing countries like India anemia is highly prevalent in the population due to the malnourished condition apart, HIV infection is one among the major cause of anemia. The outcome of certain infectious diseases including HIV is worse when the host is malnourished. HIV infection is … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,419 accessesView PDFCite