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101 results for “immunity”
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Research ArticleOpen accessEvery word in the titleASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,076 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCytomegalovirus Immunity in Pregnancy in South of IranAbdolreza Sotoodeh Jahromi, Mahin Jamshidi Makiani, Mohammad Reza Farjam et al.Problem statement: Fetal loss and abortion are responsible for significant emotional distress for couples desiring children. There are many documents which support the role of some certain asymptomatic infections such as Cytomegalovirus (CMV) in spontaneous abortion. This study was aimed to evaluate the prevalence of seropositivity for CMV IgG and IgM in women with abortion and compare it with normal … …American Journal of Infectious Diseases, Vol. 6, Issue 1 · 31 Mar 2010 · 8,147 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFoxp3-Mediated Immunity of Human Pancreatic Cancer Cell Line PANC-1Renxi Wang, Gencheng Han, Jianan Wang et al.Problem statement: More and more evidences have shown that human cancer cells can express Foxp3, the regulatory T cell-associated transcription factor. The role of Foxp3 in human cancer cells is still unclear. We detected Foxp3 expression in human pancreatic cancer cell line PANC-1. SiRNA assays showed that Foxp3 expression suppressed the expression of TGF-β and IL-10 which could induce immune … …American Journal of Immunology, Vol. 5, Issue 4 · 11 Jan 2010 · 7,367 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of a Mushroom (Coriolus versicolor) Based Probiotic on Goat HealthKingsley Ekwemalor, Emmanuel Asiamah, Sarah Adjei-Fremah, Mulumebet WorkuMaintenance of an adequate immune response is essential to goat health. CorPet biomass is a mushroom (Coriolus versicolor) based probiotic used as an immune-stimulant in man, horses and small animals. Fifteen BoerXSpanish goats were used in a crossover design to evaluate the effect of a commercial mushroom based probiotic across two periods on resilience of goats to gastrointestinal parasites in … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 3 · 4 Oct 2016 · 7,925 accessesView PDFCite
EditorialOpen accessIn the keywordsWhat You See Is What You GetSaadettin Sel, Mark A. Brown, Joachim Storsberg, Christian SchmidtThe recognition and neutralization of invading pathogens by the human immune system is designed to protect the organism. Sometimes, the checks and balances in place securing a tightly controlled immune surveillance of privileged sites are lifted in order to ensure survival of the individual at the cost of losing the functionality of an organ. Here, we use choice areas to … …American Journal of Immunology, Vol. 12, Issue 3 · 29 Sep 2016 · 6,977 accessesView PDFCite
Literature ReviewOpen accessIn the keywordsStaphylococcus aureus Vaccine Candidate from MRSA Isolates: The Prospect of a Multivalent VaccineNovra Arya Sandi, Tenri Ashari Wanahari, Isabel MacPhillamy et al.Staphylococcus aureus (S. aureus) is a major cause various infections in humans and animals throughout the world. The increasing incidence of S. aureus infection, particularly methicillin-resistant Staphylococcus aureus (MRSA) is complicated by the antibiotic-resistance phenomenon. Thus, it requires new strategies to prevent wider scale of its incidence occurring. Preventative methods against infectious diseases through vaccination can prevent, control and reduce … …American Journal of Infectious Diseases, Vol. 11, Issue 3 · 27 Aug 2015 · 8,474 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPlacebo-Driven Clinical Trials of Transfer Point Glucan #300 in Children with Chronic Respiratory Problems: Antibody ProductionVetvicka Vaclav, Richter Josef, Svozil Vladimir et al.The role of glucan in stimulation of immune reactions has been well-established. In this report, we focused on the antibody production in glucan-supplemented children with chronic respiratory problems. We measured the levels of salivary IgA, IgM and IgG in 40 children aged 8-12 years and evaluated the effects of 100 mg d-1 oral dose of glucan. We found a significant … …American Journal of Immunology, Vol. 9, Issue 2 · 5 Jun 2013 · 10,468 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMelanoma-Associated Suppression of the Dendritic Cell Lines DC2.4 and JawsiiKristian Michael Hargadon, Yonathan Tarekegne Ararso, Osric Anthony Forrest, Chad Mason HarteDendritic cells function as potent regulators of both innate and adaptive immunity to tumors and the regulatory activities of these cells are tightly linked to their maturation and activation status. Despite the critical role played by dendritic cells in the induction of anti-tumor immune responses, the number of dendritic cells that can be isolated from experimental animals is limiting and … …American Journal of Immunology, Vol. 8, Issue 4 · 3 Nov 2012 · 9,567 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Role of Treg Cells in the Cancer Immunological ResponseZhi-Zhang Yang, Stephen M. AnsellProblem statement: T cell-mediated immunosuppression has been observed for decades without clarification as to which factor was responsible for this observation. The identification of CD4+CD25+ regulatory T (Treg) cells represents a milestone in the filed of immunology and provides an explanation for T-cell-mediated immunosuppression. Although Treg cells were originally identified for their ability to prevent organ-specific autoimmune disease in mice, … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,524 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRat Cardiomyocytes Express a Classical Epithelial Beta-DefensinAnnika Linde, Gerald H. Lushington, Frank Blecha, Tonatiuh MelgarejoBeta-defensins (BDs) are classical epithelial antimicrobial peptides of immediate importance in innate host defense. Since recent studies have suggested that certain BDs are also expressed in non-traditional tissues, including whole heart homogenate, and because effector molecules of innate immunity and inflammation can influence the development of certain cardiovascular disease processes, we hypothesized that BDs are produced by cardiomyocytes as a … …American Journal of Animal and Veterinary Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 7,000 accessesView PDFCite