23 results for “female rats”

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Research ArticleOpen accessIn the abstractEndothelial Dysfunction and Insulin Resistance as Pathophysiologic Mechanisms in a Rat Model of PreeclampsiaAyman Z. Elsamanoudy, Amr M. AbbasProblem statement: To assess the plasma concentrations and placental gene expression of soluble fms like tyrosine kinase (sFlt-1), Vascular Endothelial Growth Factor (VEGF), visfatin and Tumour Necrosis Factor α (TNFα) in a rat model of preeclampsia, induced by chronic Reduction of Uterine Perfusion Pressure (RUPP) and to investigate the involvement of Insulin Resistance (IR) in the pathophysiology of preeclampsia and … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,503 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPlasma Bilirubinaemia; A Physiologic Index for Monitoring Cellular Effects of Amalar, Chloroquine, Cotecxin and FansidarE. O. Jimmy, I. F. UsohProblem statement: Antimalaria drugs are highly consumed in Africa due to increase prevalent of malaria attacks. Though the disease is often cured with some antimalarials the physiologic effects of such drugs may not be considered in pharmacologic preparations and in prescriptions. Such non consideration is likely to result in serious health problems which may outweigh the effects of malaria disease … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 7,541 accessesView PDF Cite

Research ArticleOpen accessIn the abstractThe Effects of Recombinant Human Erythropoietin and Tamoxifen on Growth and Angiogenesis of Mammary Tumor in Sprague-Dawley RatA. K. Sairah, A. Rasedee, O. Sheikh et al.Problem statement: Erythropoietin receptor (EPOR) has been detected in breast cancer cells and speculated to be involved in cancer growth, viability and angiogenesis. This has risen suspicious that EPO administration may enhance the severity of cancer. Approach: This study was undertaken to determine the effects of rHuEPO, Tamoxifen and their combination on the growth and angiogenesis of mammary tumor. Female … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 1 · 31 Mar 2009 · 7,804 accessesView PDF Cite