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Research ArticleOpen accessIn the abstractProtective Effect of Curcumin Against Hepatic Toxicity Induced by Lithium Carbonate (Li2 Co3)Gehan B.A. Youssef, Ahlam F. Hamoda, Rabab R. Elzoghby et al.The current work was done on four groups of rats (10 for each) to detect the hepato-protective characters of curcumin on the toxicity induced by lithium carbonate. The oral administration of Li2 Co3 for one-month lead to noticeable decrease in the SOD, CAT and GSH while the increase in the GPx and some histological changes in the portal tissues including … …American Journal of Pharmacology and Toxicology, Vol. 14, Issue 1 · 31 Jul 2019 · 7,603 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Acute Bronchiolitis on Cardiac Functions and Serum microRNA-122 and 499Mona Abd El-Gelel Mohamed, Khalid Mahmoud ZayedBronchiolitis is an acute inflammatory injury of the bronchioles that is usually caused by a viral infection, most commonly Respiratory Syncytial Virus (RSV). This study aimed to verify the direct injurious effect of acute bronchiolitis on the myocardium and serum level of microRNA-122 and 499 (miR-122 and miR-499) of infected infants. Serum lactate dehydrogenase (LDH), creatine phosphokinase-isoenzyme MB (CK-MB) and … …American Journal of Infectious Diseases, Vol. 12, Issue 1 · 26 Jan 2016 · 7,250 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Effects of Glucocorticoids on Trabecular Meshwork and its Role in GlaucomaAlina GenisPrimary Open-Angle Glaucoma (POAG), an optic neuropathy that is a leading cause of irreversible blindness, has been studied extensively in hopes of better understanding its underlying mechanism. Glucocorticoids (GC) are commonly used to treat inflammatory ocular conditions but are also known to increase the risk of glaucoma by raising Intraocular Pressure (IOP) in susceptible individuals, leading to steroid-induced glaucoma. Based … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 14 Oct 2015 · 8,219 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Thai Style Stretching Exercise on "Ruesi Dud Ton" on Physical Health and Oxidative Stress in Healthy VolunteerJintanaporn Wattanathorn, Tasanee Boonterm, Wipawee Thukhummee et al.Despite the health benefit reputation of Thai stretching exercise "Ruesi dud ton", no scientific evidence is available. Therefore, we aimed to determine the effect of Thai style stretching exercise on physical health and oxidative stress markers including Malondialdegyde (MDA) level and the activities of main scavenger enzymes including Superoxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GSH-Px). We had determined … …OnLine Journal of Biological Sciences, Vol. 12, Issue 4 · 22 Feb 2013 · 7,739 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvestigation of Abutment Displacement of a Full Height Integral Bridges in Dense Granule BackfillM. H. Alizadeh, A.R. Khalim Rashid, Zamri Chik, S. M. MirhosseinyProblem statement: In this study, the behavior of abutment wall in full height frame integral abutment bridges was investigated. It was seen that the effect of backfill soil resistance on behavior of abutment wall movement is mostly neglected in previous studies. In this research, the final bridge superstructure displacement under temperature-induced forces was formulated. In addition, according to the final … …American Journal of Engineering and Applied Sciences, Vol. 3, Issue 4 · 30 Nov 2010 · 8,352 accessesView PDFCite
Research ArticleOpen accessIn the abstractGeographic Information System-Allocation Model for Forest Path: A Case Study in Ayer Hitam Forest Reserve, MalaysiaI. Mohd Hasmadi, H. Z. Pakhriazad, F. S. MohamadProblem statement: Forest road planning requires a host of information, particularly the availability of spatial and non-spatial data. The requirement of a planning system or tools to gather, integrate and manipulate all data is essential. The ability of Geographic Information System (GIS) to integrate such massive information and develop a spatial model of earth features will lead to time and … …American Journal of Applied Sciences, Vol. 7, Issue 3 · 31 Mar 2010 · 8,014 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship between Nickel Exposure and the Level of Carcinoembryonic Antigen among Welders in an Automotive PlantChiang Lee Juan, Shamsul Bahri Mohd Tamrin, Syazwan Aizat Ismail et al.Background: Study on the effect of nickel exposure in the occupational setting and its association to carcinoembryonic antigen (CEA) had been studied before. Questions were raised whether the result from previous study would also show the same pattern of the urinary nickel concentration in this study. Objective: A cross-sectional study was conducted to determine the association between urine nickel concentration … …American Journal of Applied Sciences, Vol. 6, Issue 12 · 31 Dec 2009 · 7,636 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Integrated Approach to Modelling of Flood Hazards in the Rapidly Growing City of Osogbo, Osun State, NigeriaSuleiman Abdul-Azeez Adegboyega, Oluchi Christiana Onuoha, Komolafe Akinola Adesuji et al.In recent times, the swift and uncoordinated urban expansion in the medium sized city of Osogbo has increasingly encroached on the environmental sensitive areas. This uncoordinated exploitation of the ecological fragile areas for urban development has triggered urban flooding, which poses serious threat to human lives and properties in the city. This study therefore utilized geospatial technologies to generate flood … …Space Science International, Vol. 4, Issue 1 · 8 Jan 2018 · 13,829 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling Hepatocellular Toxicity of Enavatuzumab, a Humanized Anti-TweakR AntibodyDonghee Choi, Yanhong Zhu, Debra Tien Chao et al.In a Phase 1 clinical study, treatment with enavatuzumab, a humanized monoclonal antibody to TweakR, resulted in liver toxicity in a subset of patients. The objective of this current study was to evaluate the ability of preclinical studies to predict liver toxicity in humans. Enavatuzumab was evaluated in cynomolgus monkeys, where serum liver enzyme and cytokine levels were measured and … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 2 · 9 Nov 2017 · 7,719 accessesView PDFCite
Research ArticleOpen accessIn the abstractChronic Mental Stress Induces Reversible Reduction of Natural Killer Cells and CD56dim SubpopulationManar M. IsmailGenerally, studying to be a health care provider is a stressful and demanding field and the students have to face many stressors that may affect their general health status including the immune system. This work aimed at studying the effect of prolonged naturalistic life-stress exposure on the percentage of peripheral blood T-lymphocytes and Natural Killer (NK) cells in female laboratory … …American Journal of Immunology, Vol. 13, Issue 3 · 30 Aug 2017 · 7,792 accessesView PDFCite