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235 results for “drug use”
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Research ArticleOpen accessIn the abstractAdverse Drug Reaction Detection Using Latent Semantic AnalysisAhmed Adil Nafea, Nazlia Omar, Mohammed M. AL-AniDetecting Adverse Drug Reactions (ADRs) is one of the important information for determining the view of the patient on one drug. Most studies have investigated the extraction of ADRs from social networks, in which users share their opinion on a particular medication. Some studies have used trigger terms to detect ADRs. Such studies showed remarkable performance in terms of extracting … …Journal of Computer Science, Vol. 17, Issue 10 · 28 Oct 2021 · 7,816 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of the Utility of MPT64, Drug Susceptibility Testing and Tuberculosis/Nontuberculous Mycobacteria Reverse Transcription Polymerase Chain Reaction for Tuberculosis Diagnosis and Efficiency Compared with Traditional CultureHo Keun Choi, Ga Yeon Kim, Tae Soung Kim, Jae Kyung KimDefining the molecular mechanisms underlying the dormant state of Mycobacterium tuberculosis (MTB) is essential for developing more effective treatments for tuberculosis (TB) infection. We investigated the positivity and resistance rates of TB tests on 6,174 samples referred to a single hospital. Of these, 342 cases (5.5%) were confirmed as positive by acid-fast bacilli staining, 243 cases (71.1%) were detected as … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 5 Dec 2024 · 4,211 accessesView PDFCite
Research ArticleOpen accessIn the abstractSemSimp: A Parametric Method for Evaluating the Semantic Similarity of Digital ResourcesAntonio De Nicola, Anna Formica, Ida Mele, Francesco TaglinoAbioui, H., Idarrou, A., Bouzit, A., & Mammass, D. (2018). Towards a Novel and Generic Approach for OWL Ontology Weighting. Procedia Computer Science, 127, 426–435. https://doi.org/10.1016/j.procs.2018.01.140 Adhikari, A., Dutta, B., Dutta, A., Mondal, D., & Singh, S. (2018). An intrinsic information content-based semantic similarity measure considering the disjoint common subsumers of concepts of an ontology. Journal of the Association for … …Journal of Computer Science, Vol. 20, Issue 8 · 27 May 2024 · 5,778 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanism Analysis of Artemisinin and Artesunate as Lung Cancer Therapy Agents Through in Silico MethodDidik Harmoko, Vivitri Dewi Prasasty, Adi YulandiSeveral in vitro studies have focused on the ability of artemisinin and its derivatives to suppress lung cancer cells, but there are still many biological processes and mechanisms, such as the interactions between the active compounds (ligands) and receptors that are not well understood and require further research. Drug targeting for lung cancer will be more precise and the inhibition … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 6,149 accessesView PDFCite
Review ArticleOpen accessIn the abstractMechanistic Insights of Actions of Metal Nanoparticles on Multidrug-Resistant BacteriaSeham S. Alzahrani, Hani Mohammed Ali, Mohamed M. AhmedMultidrug-Resistant bacteria (MDR) are the most serious threat to public health. The number of infections caused by resistant strains is on the rise all over the world. At this time, new techniques for developing antimicrobial drugs are becoming necessary. Metallic Nanoparticles (MNPs) in the biomedical field are one of the most promising methods to overcome antibiotic resistance. Nanoparticles have recently … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 22 Jun 2021 · 6,379 accessesView PDFCite
Case ReportOpen accessIn the abstractA Reasonable Outcome with Systemic Corticosteroids in a Case of Ibuprofen Induced Stevens-Johnson SyndromeElif Güdeloğlu, Volkan Emir AltanBoth Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are idiosyncratic severe mucocutaneous reactions, usually to drugs or infections, characterized by blistering and epithelial sloughing. Although rare, SJS and TEN are destructive diseases; in serious cases the acute phase may be followed by a variety of systemic complications, including multiorgan failure and death. Ibuprofen is a universal antipyretic and analgesic … …American Journal of Immunology, Vol. 16, Issue 1 · 4 Sep 2020 · 7,455 accessesView PDFCite
Literature ReviewOpen accessIn the abstractDevelopment of Azithromycin Resistance in Streptococcus pneumoniae in the Setting of Trachoma Mass Drug Administration: A Systematic ReviewNazia Khan, Barbara Lachana Onen, Robin Hilder, Robin BaileyTrachoma is a blinding eye disease caused by the bacterium Chlamydia trachomatis. The current global elimination of trachoma initiative includes the use of mass drug distribution of azithromycin in areas where the prevalence of follicular trachoma is >10% in children aged 1-9 years. This study aims to investigate the high quality evidence of whether mass drug administration for trachoma causes … …American Journal of Infectious Diseases, Vol. 16, Issue 3 · 24 Jul 2020 · 7,599 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Development of New Molecules Having Antiemetic Activity Using Molecular ModelingKhalil Errahmane Kanouni, Yacine BenguerbaThe solubility of a drug in water or in the blood represents the most desired parameter in medicine. Our aim is to obtain molecules with properties more effective than those of metoclopramide. In this work, two molecules with high solubility are constructed. Metoclopramide (a benzamide derivative) is a dopamine receptor antagonist used as an antiemetic drug. Its solubility in water … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,670 accessesView PDFCite