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47 results for “collagen”
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Research ArticleOpen accessIn the keywordsAn Induced Hematoma in Caudoputamen Nuclei in Rats Causes Central Pain when the Thalamus is also Implicated and the Central Sensitization is Reversed with GabapentinP. P. Lema, P. VachonProblem statement: The objective of this study was to evaluate pain sensitisation in rats following the induction of an intracerebral hemorrhage by injecting a collagenase solution in the caudoputamen nucleus of the right basal ganglia and to evaluate gabapentin as an analgesic for central pain. Approach: Thirty male Sprague-Dawley rats weighing between 175-300 g were used. In a first experiment, … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 10 Mar 2012 · 8,167 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of Intraperitoneally Injection of Different Doses of Lovastatin on Pain and Inflammatory Response Induced by Formalin in MiceKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methyl Glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality. Their lipid-lowering actions are by reversible and competitive inhibition of the enzyme HMG-CoA reductase, a precursor of cholesterol. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels, such as … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,679 accessesView PDFCite
Research ArticleOpen accessIn the abstractCrack Bridging and Deflection Toughening Mechanisms of Staggered Hydroxyapatite Lamellar Microstructure in BoneYuxi Liu, Xiaohui He, Shuge Li, Zhangdong SunThe observation experiment results of the microstructure of tibial cortical bone show that the cortical bone is a layered bio-ceramic composite material composed of Hydroxyapatite (HAP) and collagen arranged alternately. HAP is a reinforcing phase and accounts for a large proportion in cortical bone. These hydroxyapatites have long and thin sheet-like structures parallel to the outer surface of the bone, … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 31 Jul 2026 · 890 accessesView PDFCite
Research ArticleOpen accessIn the abstractComputational Prediction of Diabetic Nephropathy-Associated Comorbidities and Their Key Genes by Analyzing RNA-Seq DataChaity Paul, Md. Ashiq Uddin, Rupa Dey et al.Diabetic Nephropathy (DN) is a complex health condition that leads to various kidney diseases. According to the World Health Organization, over 2 million deaths have been reported due to diabetes and diabetes related kidney diseases in 2021. And at the recent 78th World Health Assembly, chronic kidney disease was reported to be one of the most common diabetes-related complications, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 19 May 2026 · 1,667 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessing the Toxic Effects of Topik80ec on Rabbit Testicular Morphometry and HistologySamia Rebahi, Alouani Abdelouahab, Meguini Mohamed Nadir et al.This study aimed to investigate the toxic impact of Topik80ec on rabbit testes through morphometric and histological analyses. Twenty-four adult male domestic rabbits (Oryctolagus cuniculus) were used, where three experimental groups, G1, G2, and G3, were assigned and provided escalating dosages of Topik80 EC for a duration of four weeks, while one group served as the control group and received … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 14 Sep 2024 · 5,015 accessesView PDFCite
Research ArticleOpen accessIn the abstractMMP-9 is a Potential Prognostic Marker of Left Ventricular Remodeling in Patients with Coronary Artery DiseaseMikhail Aleksandrovich Popov, Anastasia Vladimirovna Poznyak, Dmitry Valerievich Shumakov et al.Matrix Metalloproteinase-9 (MMP-9) emerges as a promising prognostic marker for assessing left ventricular remodeling in patients with coronary artery disease, particularly in the context of Ischemic Heart Disease (IHD) complicated by left ventricular aneurysm. In this study, we conducted two parallel investigations to explore the prognostic significance of MMP-9 in patients with multivessel coronary artery disease undergoing left ventricular reconstruction … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 11 Jul 2024 · 4,310 accessesView PDFCite
Research ArticleOpen accessIn the abstractUltrastructural Morphology of the Muscle System Organization in the Trematode Typhlocoelium cucumerinumIrina Yurievna Chidunchi, Ainagul Balgauovna Kaliyeva, Natalya Petrovna Korogod et al.Trematodes, also known as flatworms, are a diverse group of parasitic organisms that live in a variety of ecosystems, from freshwater to marine habitats. Their complex life cycle often involves intermediate and definitive hosts and multiple developmental stages. Trematodes have unique morphological features that allow them to adapt, move and parasitize within host tissues and organs. The parasitic lifestyle of … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 1 Jun 2024 · 5,112 accessesView PDFCite
Research ArticleOpen accessIn the abstractHistomorphochemical Studies on Accessory Glands of Iraqi Blackbuck (Caprus Hircus)Waleed J. A. Al-Kelaby, Wafaa Hadi Mousa AL-Hashem, Zahraa S. M. Al Kaabi et al.Thevarious species' male accessory genital glands vary and are intimately relatedto the pelvic urethra. These glands secrete nutritional substances, buffers,and mucous to increase volume, serve as lubricants, reduce the minor acidity ofvaginal contents and make the environment more hospitable to motile sperm. Thisstudy aims to study the histological and histochemical structure of the maleaccessory sex glands in caprine Iraqi breeds. … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 4 · 25 Nov 2022 · 5,382 accessesView PDFCite
Research ArticleOpen accessIn the abstractGelatin Extraction of Alaska Pollock (Theragra chalcogramma) Dry SkinYanan Li, Fangyuan Chen, Jiong Zou et al.Alaska Pollock is rich in resource. And during its processing, skin is peeled as byproducts. The skin of Alaska Pollock contains lots of collagen or gelatin, promising materials, which can be used in food, cosmetics, biomedical and pharmaceutical industries. Extracting collagen from the dry skin of Alaska Pollock is studied in this study to provide a better basement for fully … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 1 · 28 Jan 2018 · 9,498 accessesView PDFCite