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52 results for “antioxidant enzymes”

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Research ArticleOpen accessIn the abstractTrilobatin Possesses Protective Potentials on H2O2-Induced HepG2 Cells by Suppressing Oxidative Stress: Involvement of Nrf2/Keap1 Signal PathwayYuhan Zhai, Yuqing Zhang, Yaping Li et al.Trilobatin, a natural dihydrochalcone compound, possesses various biological activities. However, few investigations have been carried out on the mechanisms of trilobatin against oxidative stress. To comprehend the effects and mechanism of trilobatin on oxidative stress after hepatic injury, H2O2-induced HepG2 cells were used in this research. The results indicated that trilobatin enhanced the viability and improved the apoptosis morphology of … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 22 Dec 2023 · 5,089 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Mercuric Ion on the Oxidant Response and Calcium Ion in the Protoplasts of Arabidopsis ThalianaJun Xing, Rui Wu, Hui Yu et al.As a non-essential element for plant growth and development, the heavy metal mercury (Hg) has significant toxicity to plants. The aim of this study was to investigate the effect of mercuric ion (Hg2+) on the oxidant response and calcium ion (Ca2+) in the protoplasts of Arabidopsis thaliana. The protoplast cells were exposed to 5.0, 10.0, and 20.0 mmol/L Hg2+ for … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 29 Aug 2023 · 4,966 accessesView PDFCite
Research ArticleOpen accessIn the abstractNuclear Factor Erythroid-2-Related Factor 2 (Nrf2) Signalling Pathway and Apoptosis Impact on the Effect of Tetramethylpyrazine against H2O2-Damage in Human Hepatic Cell Line (LO2 Cells)Songbo Guo, Xinglin Han, Baoguo Sun et al.As an active component in traditional Chineseherbal medicine, Tetramethylpyrazine (TMP)played a critical role in the treatment of cardiovascular, cerebrovascular, andeye diseases. In this study, the TMP has obtained from the Chinese herbalmedicine Ligusticum chuanxiong and investigated the protective effects of TMPon oxidative damage in human LO2 cells with the treatment ofdifferent concentrations of TMP. The results showed that TMP reserved … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 6 Sep 2022 · 5,659 accessesView PDFCite
Research ArticleOpen accessIn the abstractAqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in VitroAyodeji O. Falade, Goodness I. Omolaiye, Kayode E. Adewole et al.Neurological disorders remain a global health challenge, with Alzheimer’s Disease (AD) as the most famous cause of dementia in old people. Nevertheless, culinary spices and herbs have shown promising potentials in the management of neurological diseases. This study aimed at investigating the neuroprotective property of aqueous extracts of bay leaf (Laurus nobilis) and rosemary (Rosmarinus officinalis) by assessing the antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 25 Jan 2022 · 7,961 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Bioaccumulation and Detoxification Mechanism of Neodymium on the Shoot of Rice SeedlingsKailun Shi, Cheng Kun Liu, Keliang Lyu et al.Neodymium (Nd) potentially pollutes environment for its wide usage in agriculture and industry. In this study, the chemical forms of Nd and effect of Nd on rice shoots were studied after rice seedlings were exposed with 0, 1, 10, 100 and1000 μM Nd. The higher concentration of Nd inhibited shoot growth, but the lower concentration of Nd induced shoot growth. … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 11 Apr 2021 · 6,294 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Oxidative Stress during Pregnancy on Obstetric Pathology Development in High-Yielding Dairy CowsInna Ventsova, Vladimir SafonovThe study aimed to examine the processes of oxidative stress and their intensity depending on the state of the antioxidant system in dairy cows. The study was conducted in 2018-2019 on the territory of the Druzhba breeding factory (Voronezh region, Russia) and involved 154 cows divided into 4 groups. Group 1 consisted of healthy animals (n = 83). Group 2 … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 1 · 19 Jan 2021 · 6,728 accessesView PDFCite
Research ArticleOpen accessIn the abstractGlutathione S-transferase (T1 & M1) Null Genotypes as Risk Determinants in Sudanese for Developing Type Two Diabetes MellitusGaafar Mahmoud, Hisham Mohamed Abdelrahim, Abed Al Salam Aljahmany, Eltayeb Mohamed Ahmed TayrabGlutathione S-transferases (GSTT1 and GSTM1) are globular proteins responsible for the detoxification of xenobiotics and the prevention of oxidative damage. Functional polymorphisms of the antioxidant glutathione and enzymes have a role in the pathogenicity of T2DM and its complications. The present study is aimed to assess association between GSTM1 and GSTT1 genetic polymorphisms with T2DM in Sudanese people. This case-control … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 16 Oct 2020 · 6,426 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnticonvulsant Activity of Hydroalcoholic Phoenix dactylifera Fruit Extract and Pimpinella anisum Oil in MiceSameh Mohamed Mostafa EL-Nabtity, Ahmed Shaban Abdelaziz, Manar Salah Moselhi, Mario GiorgiEpilepsy is a group of long-term neurological disorders characterized by epileptic seizures. The present study sought to investigate the anticonvulsant and neuroprotective Activity of Hydroalcoholic Phoenix dactylifera fruit extract (HAPD) and Pimpinella Anisum Oil (PAO) against Pentylenetetrazole (PTZ) and Maximal Electric Shock (MES) induced a seizure in mice. Mice groups were treated with HAPD1000 mg/kg, PAO 4 ml/kg. The onset … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 2 · 25 May 2019 · 7,596 accessesView PDFCite
Research ArticleOpen accessIn the abstractOxidative Stress and Reproductive Damage Induced by Lead Acetate in Female Guinea Pig (Cavia porcellus): Curative Effects of Hydroethanolic Extract of Spirulina platensisDeutcheu Nienga Sorelle, Ngoula Ferdinand, Manfo Tsague Faustin Pascal et al.This study was aimed at evaluating the curative effects of Hydroethanolic Extract Of Spirulina platensis (HESP) on the reproductive function of female Guinea pig exposed to oxidative stress. Sixty females, 3-4 months old, weighing 300-400 g were divided into six groups (10 animals/group). The neutral control received distilled water, the negative control was treated with lead acetate at a dose … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 1 · 8 Apr 2019 · 7,424 accessesView PDFCite
Research ArticleOpen accessIn the abstractASCORBIC ACID FOLIIAR SPRAY COUNTERACTING EFFECT OF SALINITY ON GROWTH, NUTRIENTS CONCENTRATIONS, PHOTOSYNTHESIS, ANTIOXIDANT ACTIVITIES AND LIPID PEROXIDATION OF BEAN (PHASEULUS VULGARIS L.) CULTIVARSZeinab A. Salama, El-Zanaty A.A. Abou El-Nour, Mohamed M. El Fouly, Alaa A. GaafarA water culture experiment was carried out in the Department of Fertilization Technology at National Research Centre, Cairo, Egypt, to investigate the effect of Ascorbic Acid (AsA) foliar application and salinity stress (100 ppm and 100 mmoL NaCl) on growth, nutrients concentration and some biochemical parameters of two kidney bean (Phaseulus Vulgaris L.) cultivars. Salinity caused significant reduction in growth … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 3 · 16 May 2014 · 7,906 accessesView PDFCite