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115 articles for “antibody”
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Research ArticleOpen accessEvery word in the titleDetermination of the Salivary Anti-Phenolic Glycolipid-1 Antibody in Leprosy Patients as a Tool to Monitoring MultidrugtherapyN. L.B. Bonfitto, A. C.F. Motta, R. B. Furini et al.Problem statement: The upper airways has a great importance as a route of M. leprae infection and because of the possibility of identifying relevant tools by systematic patient evaluation, the detection of leprosy patients by means of salivary markers becomes important. The aim of this study was to analyze anti-phenolic glycolipid 1 (anti-PGL-1) salivary and serum titers as parameters for … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 8,117 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePurification of A Recombinant Thrombin-like Enzyme, Gloshedobin by Egg Yolk Antibody-Coupled AdsorbentsQing Yang, Xuyu Lei, Jianqiang Xu, Lijia AnThe gloshedobin, a snake venom thrombin-like enzyme was biosynthesized in the soluble form and purified by egg yolk antibody-coupled adsorbents from E. coli. As His-tag is not favored from the point of view of high-level and soluble expression, we herein constructed a recombinant gloshedobin without His-tag and developed a novel egg yolk antibody (IgY)-immunoaffinity chromatography for its purification in a … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 1 · 31 Mar 2005 · 6,690 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAttempts to Stimulate Immunology Responses by Intramuscular and Intraperitoneal Delivery of EPS-Adjuvanted Mannheimiosis VaccineGhaith Hussein Mansour, Laith Abdul Razzak, Hassan Ibrahim Sheikh, Mohd Effendy Abd WahidThis study was conducted on 48 male Sprague Dawley rats to determine the immunological responses of experimental adjuvanted vaccines of Mannheimia haemolytica A2 (M. haemolytica A2) injection and to observe their protection level upon live M. haemolytica A2 challenge. Forty-eight clinically healthy Sprague Dawley rats were divided into four groups; Groups 1 and 2 were vaccinated intramuscularly and intraperitoneally, respectively, … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 4 · 22 Dec 2022 · 5,352 accessesView PDFCite
Research NotesOpen accessIn the keywordsIndividualizing Periods of Commercial Exclusivity to Control Pricing for Drugs and BiologicsCallie M. Blase, Brandon K. Rouault, Maia B. Zoller et al.The pricing for immunologic agents and antibody-based therapeutics has increased precipitously in recent years. Among the key contributors to price hikes is the static practice of granting commercial exclusivity to innovator drugs and biologics. Herein, we present a mechanism for individualizing periods of commercial exclusivity to control pricing for drugs and biologics. …American Journal of Immunology, Vol. 15, Issue 1 · 13 Sep 2019 · 7,011 accessesView PDFCite
Research ArticleOpen accessIn the keywordsComparative Analysis of Various Diagnostic Methods for Trichomonas Vaginalis Infection in Trinidad and TobagoAruna Kumari Divakaruni, Bisram Mahabir, FA Orrett et al.Trichomonas vaginalis infection is a common sexually transmitted infection in the reproductive age group, which may lead to complications. Wet mount examination is the most common test for diagnosis, but it has low sensitivity. Fluorescent antibody staining can be used for diagnosis, but it is expensive and requires special microscopic facility. Culture is considered as the gold standard, but it … …American Journal of Infectious Diseases, Vol. 14, Issue 2 · 6 Oct 2018 · 8,057 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCurrent Advances in Zika Virus Transmission: Urgency for Effective Therapeutics and PreventionYash Raj, Swatantra Kumar, Amrita Haikerwal et al.Global emergence of Zika Virus (ZIKV) with prevalent outbreaks has been reported in numerous countries of South America, Central America and the Caribbean region. According to recent World Health Organization (WHO)-ZIKV situation report, 84 countries/territories/subnational areas represented with established mosquito-borne transmission of ZIKV. As of 10 August 2017, cumulative Zika cases and congenital syndrome associated with Zika virus reported by … …American Journal of Infectious Diseases, Vol. 13, Issue 2 · 2 Oct 2017 · 7,798 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDUAL ROLES OF CANCER CELL-EXPRESSED IMMUNOGLOBULINS IN CANCER IMMUNOLOGYGregory Lee, Cheng-Yuan Huang, Suefay Liu et al.While the expression of immunoglobulins and T cell receptors on cancer cells has been well-established for decades, the potential roles and mechanisms of action of these cancerous antigen receptors have not been fully elucidated. A monoclonal antibody designated as RP215, which reacts specifically with the carbohydrate-associated epitope located on the heavy chain region of cancerous immunoglobulins and T cell receptors, … …American Journal of Immunology, Vol. 10, Issue 3 · 2 Oct 2014 · 7,870 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCancerous Immunoglobulins and CA215: Implications in Cancer ImmunologyGregory LeeImmunoglobulins are typically expressed by B cells in our normal immune system. However, certain normal human tissues, such as hyperplastic epithelial cells, cells of the immunologically privileged sites and the majority of cancer cells, have also been found to be sites of immunoglobulin production. Current research is lacking in regards to the differential immunoglobulin expression, the underling mechanisms of action … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Sep 2012 · 8,942 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStimulatory Effects of Dihydroartemisinin on the Leucocyte Population of Wistar Albino RatsU. A. Utoh-Nedosa, P. A. Akah, C. O. Okoli et al.Problem statement: Five dosages of Dihydroartemisinin (DHA) which included 1 mg kg-1; a repeated dose of 1; 2; 60 and 80 mg kg-1 were administered orally to albino rats for 5 days. The results of the study showed that dihydroartemisinin treatment significantly elevated the total white cell count (p<0.01); the percentage neutrophil count (p<0.01) and the percentage lymphocyte count (p<0.05). … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 17 Nov 2011 · 7,350 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSeroprevalence of Neospora Caninum in Stray DogsGaredaghi YagoobProblem statement: To investigate anti-Neospora caninum antibodies in stray dogs living in Tabriz city, 100 blood samples were collected. Serum samples were screened for detection of anti-N. caninum IgG antibodies using Indirect Fluorescent Antibody Test (IFAT; ≥50). Antibodies were seen in 31 (31%) of 100 dogs. Approach: The IFAT antibody titers were as follows: 1:50 in 11 dogs, 1:100 in … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 3 · 5 Oct 2011 · 7,936 accessesView PDFCite