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117 results for “antibodies”
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Research ArticleOpen accessIn the keywordsIgG Subclass Variation of a Monoclonal Antibody Binding to Human Fc-Gamma ReceptorsRekha Patel, Krista K. Johnson, Bruce A. Andrien, Paul P. TamburiniThe importance of human Fc receptors in immune regulation is well known. Their role is critical not only in the recruitment of cellular effector functions but also in regulating the balance in the periphery between autoimmunity and tolerance. Despite their central importance, there is a dearth of literature on controlled numeric comparisons in affinities of antibody subclasses for gamma receptors. … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 8,065 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSerological Evidence of Recent Dengue Virus Infection Among Febrile Children in a Semi Arid ZoneFaneye Adedayo, Idika Nioma, Motayo Babatunde Olanrewaju et al.Presence of Dengue virus has been established in Nigeria; owing to the severity of this disease and its attendant complications we investigated the presence of this virus serologically in febrile Nigerian children under 5 years of age from Ilorin. Blood samples were tested from 130 children under the age of 5 years for the presence of IgM antibodies against all … …American Journal of Infectious Diseases, Vol. 9, Issue 1 · 1 Feb 2013 · 7,894 accessesView PDFCite
Research ArticleOpen accessIn the keywordsComparison of Radial and Axial Flow Chromatography for Monoclonal Antibody Downstream Processing at Bench and Pilot ScalesAli Demirci, Frank Leu, F. James BaileyAxial Flow Chromatography (AFC) is widely used for the purification of therapeutic Monoclonal Antibodies (MAbs). However, AFC columns can generate high pressure drops across the resin bed, preventing operation of the column at high flow rates especially at pilot or manufacturing-scales. Radial Flow Chromatography (RFC) was developed to provide lower pressure drops during chromatographic separations. In these studies, small and … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 4 · 25 Dec 2012 · 11,508 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAnti-β2 Glycoprotein-I Antibody in Acute Myocardial InfarctionMohammad Shojaei, Abdolreza Sotoodeh Jahromi, Hamideh Ebadat et al.Problem statement: Ischemic cardiac manifestations have been reported in a various percentage of patients with anti-phospholipid antibodies. Data concerning the relation between anti- Phospholipid (aPL) antibodies and myocardial infarction in subjects without evidence of overt autoimmune disease are conflicting. Anti-beta2 glycoprotein-I (anti-beta2-GPI) antibody is detected in various diseases like rheumatoid arthritis, systemic lupus erythematosus and anti-phospholipid antibody syndrome. The study … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 18 Jul 2011 · 7,051 accessesView PDFCite
Review ArticleOpen accessIn the keywordsDNA Vaccination Associated with Eliminating Inheritance Risks during Embryo Development: A ReviewRia MargianaThe process of immunization using modified DNA is essential whenever scientists desire to trigger an artificial response in the host’s body to improve immunity. The use of DNA vaccines awakens the somatic cells of the host to produce antigens that will assist the body to prepare to fight infections through preventive measures triggered by the vaccines. These biological inventions have … …OnLine Journal of Biological Sciences, Vol. 16, Issue 2 · 26 May 2016 · 6,873 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIntroduction of Three Complementary Technologies into Clinical Medicine: Development of New Diagnostic and Prognostic ParametersGernot P. Tilz, Marco Wiltgen, Ulrike Demel et al.Molecular medicine leads us to understand some diseases at the molecular level. Examples are the analysis of immune complexes and receptor - anti receptor compounds used in clinical medicine. Structural changes of some serum proteins occur in inflammation, neoplasie and autoimmunity. The detection and analysis of such structural modifications may offer a new field for the diagnosis, prognosis and therapy … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 6,956 accessesView PDFCite
Research ArticleOpen accessIn the abstractAttempts to Stimulate Immunology Responses by Intramuscular and Intraperitoneal Delivery of EPS-Adjuvanted Mannheimiosis VaccineGhaith Hussein Mansour, Laith Abdul Razzak, Hassan Ibrahim Sheikh, Mohd Effendy Abd WahidThis study was conducted on 48 male Sprague Dawley rats to determine the immunological responses of experimental adjuvanted vaccines of Mannheimia haemolytica A2 (M. haemolytica A2) injection and to observe their protection level upon live M. haemolytica A2 challenge. Forty-eight clinically healthy Sprague Dawley rats were divided into four groups; Groups 1 and 2 were vaccinated intramuscularly and intraperitoneally, respectively, … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 4 · 22 Dec 2022 · 5,352 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeroprevalence and Co-Infection of Human Papillomavirus (HPV) Genotypes Among HIV PositivesOkoro Nworie, Euslar Onu, Ogbonnaya Ogbu et al.Human Papillomavirus (HPV) infection is now considered a sexually transmitted disease with particular types being highly oncogenic in nature. High-risk HPV virus infection is a cause of nearly all cases of cervical cancer amongst women. This study determined the seroprevalence of HPV type-16 and type-18 among HIV positive. Blood samples were processed using ELISA test kit and PCR technique. ELISA … …American Journal of Infectious Diseases, Vol. 16, Issue 1 · 9 Mar 2020 · 7,094 accessesView PDFCite
Case ReportOpen accessIn the abstractAn Unusual Case of Pyrexia with BlindnessNaveen, Bharat Bhushan Sharma, Annu Kumari Saw, Akash ParuthiPyrexia is a common clinical problem; causes may vary depending on the clinico- epidemiological settings. Infectious diseases form the most common cause of fever especially in the immunocompromised category. The cause may not be obvious from the initial presentation and a stepwise workup is usually required. Potential diagnostic clues are very important in this regard. Our patient had a fever … …American Journal of Infectious Diseases, Vol. 20, Issue 3 · 2 Dec 2024 · 4,932 accessesView PDFCite
Research ArticleOpen accessIn the abstractNewcastle Disease Virus VII.2 First Record in KazakhstanMarina Kopochenya, Belan Astemirov, Karina Ivanova et al.Although the NDV vaccination program is quite intensive in Kazakhstan, disease outbreaks are occurring repeatedly. During the fall season of 2023, we effectively achieved the isolation of the Newcastle Disease Virus (NDV) specifically, the class II genotype VII.2. This was accomplished in the context of an outbreak within industrial poultry layers located in the northern geographical sector of Kazakhstan. The … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 3 · 12 Sep 2024 · 5,349 accessesView PDFCite