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EditorialOpen accessIn the abstractInternational Journal of Research in Nursing: Contribution to Basic and Clinical Nursing ScienceVictor V. ChabanTaking into consideration the expansive growth of scientific knowledge, a successfultranslation of clinical or basic observations into new forms of therapy wouldhave a great impact on society. These days, acknowledging and responding to publicconcerns are just as important for the investigator as performing the researchstudies themselves. Clinicians and practitioners have become more aware of therole of research in their line … …International Journal of Research in Nursing, Vol. 6, Issue 2 · 26 Aug 2015 · 6,916 accessesView PDFCite
EditorialOpen accessIn the abstractVisceral Pain: Basic Research Concepts and Therapeutic InterventionsVictor V. ChabanThe accumulation of nociceptive diseases that limit normal body functions is a major risk factor for a disability, and visceral pain is one of the most prevalent human health problems. Additionally, many pain-associated diseases are accompanied by the concomitant decline in cognitive and motor performance. The complex interplay and balance between diverse signal transduction mediators, genetic background and environmental factors … …International Journal of Research in Nursing, Vol. 6, Issue 2 · 26 Aug 2015 · 7,148 accessesView PDFCite
Research ArticleOpen accessIn the abstractIMPACT OF DEHYDROEPIANDROSTERONE IN PREVENTION OF PARACETAMOL INDUCED NEPHROTOXICITY IN RATSAbbas O. ElkaribParacetamol (PCM) overdose can cause nephrotoxicity with oxidative stress as one of the possible mechanisms mediating the event. However, Dehydroepiandrosterone (DHEA), the major secretory product of the human adrenal gland, has been shown to possess a multi-targeted antioxidant activity which is also effective against lipid peroxidation induced in various animal models and against various human disorders. In this study, the … …Current Research in Medicine, Vol. 5, Issue 1 · 26 Mar 2014 · 7,566 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECTIVENESS OF A PARTICIPATORY ACTION ORIENTED TRAINING INTERVENTION APPROACH AMONG HARVESTERS IN OIL PALM PLANTATIONNg Yee Guan, Shamsul Bahri Mohd Tamrin, Ismi Arif Ismail et al.Consistent with the global demand for palm oil, the intensified upstream harvesting activities of oil palms’ fresh fruit bunches, despite the harvesters evidences of various ergonomics risk factors leading to musculoskeletal disorders should be a cause for concern. Thus, this study describes the effectiveness of a modified and locally adapted Participatory Action-Oriented Training intervention program in improving the working environment … …American Journal of Applied Sciences, Vol. 11, Issue 4 · 8 Feb 2014 · 8,980 accessesView PDFCite
Research ArticleOpen accessIn the abstractRetinal Image Analysis for Abnormality Detection-An OverviewR. Karthikeyan, P. AlliProblem statement: Classification plays a major role in retinal image analysis for detecting the various abnormalities in retinal images. Classification refers to one of the mining concepts using supervised or unsupervised learning techniques. Approach: Diabetic retinopathy is one of the common complications of diabetes. Unfortunately, in many cases, the patient is not aware any symptoms until it is too late … …Journal of Computer Science, Vol. 8, Issue 3 · 24 Jan 2012 · 7,280 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuercetin Liposomes via Nasal Administration Reduce Anxiety and Depression-Like Behaviors and Enhance Cognitive Performances in RatsTerdthai Tong-Un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the prevalence of neuropsychological disorders particularly anxiety, depression and dementia are increase. Many strategies have been developed in order to increase the efficiency of treatment and decrease side effects. Oxidative stress has been reported to play an important role on various path physiological states. Quercetin is a flavonoid commonly found in fruits and vegetables. It has … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,034 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntrinsically Unstructured Proteins: Potential Targets for Drug DiscoveryPathan Salma, Chintan Chhatbar, Sriram SeshadriProblem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by their unstructured nature in the unbound state, provides a level … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,578 accessesView PDFCite
Research ArticleOpen accessIn the abstractRedox Sensing and Cardiac Myocyte Loss: Some Recent InsightsShyamal K. GoswamiGeneration of reactive oxygen-nitrogen species (ROS/RNS) has long been ascribed to pathophysiological conditions like ageing, neurodegenerative and cardiovascular disorders. However, more recent evidences suggest that while generation of ROS/RNS at a higher threshold is deleterious, at a lower dose these can act as second messengers, influencing specific cellular events like cell growth and differentiation, embryonic development, protection against ischemic injuries … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,349 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuropsychological Complications of HIV Disease and Substances of AbuseLisa R. Norman, Anil KumarIn the last decade, it has become increasingly apparent that neuropsychological deficits and impairments are associated with HIV infection. Given that antiretroviral therapies have extended the life expectancy of HIV-infected persons, it becomes critical to focus on the physical and mental health of these patients. Understanding the neuropsychology of HIV disease can provide insight into improving mental health, functional capacity … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,401 accessesView PDFCite
Research ArticleOpen accessIn the abstractCortisol Response Mediates HIV-1-Related Cognitive Deficits Among Injecting Drug AbusersRaymond L. Ownby, Drenna Waldrop-Valverde, Adarsh M. Kumar et al.The cortisol response is an important measure of the endocrine activity to environmental challenges and has been related to cognitive function and mood. Previous studies have shown that the cortisol response to stress is dysregulated in persons with HIV-1 infection. Since cortisol is neurotoxic and its levels have been related to cognitive dysfunction in various disorders, it is possible that … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,759 accessesView PDFCite