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Research ArticleOpen accessEvery word in the titleAnalysis of Interferon-Gamma Release Assay Results for Latent Tuberculosis Infection Diagnosis at a Referral Clinical Laboratory in South KoreaTae Soung Kim, Ga Yeon Kim, Young Ki Lee, Jae Kyung KimThe world health organization states that individuals with Latent Tuberculosis Infection (LTBI) are infected with Tuberculosis (TB) bacteria but do not show symptoms of active disease. However, they are at possibility of developing vigorous TB and potentially transmitting the illness to others. In 2018, South Korea reported a 14.8% positivity rate in LTBI screening, with higher rates observed among older … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 25 Oct 2023 · 6,033 accessesView PDFCite
Case ReportOpen accessEvery word in the titleNon-Specific Interstitial Pneumonia Overlapping Tuberculosis: A Diagnostic Challenge in ElderlyPradeep Chakaravarthy, Divanshee Sharma, Manjunath Totaganti et al.Non-Specific Interstitial Pneumonia (NSIP) is linked to numerous etiologies, including connective tissue diseases, certain drugs, HIV and idiopathic causes. We present a case of an 82-year-old woman with subacute onset shortness of breath as the presenting feature of Non-specific interstitial pneumonia. Chest imaging demonstrated bilateral infiltrates and tentatively diagnosed as NSIP and started on Tyrosine kinase inhibitor - Nintedanib. But … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 5 Jan 2022 · 6,168 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMycobacterium tuberculosis Complex Mutations in Drug Resistant Clinical Isolates from Southwest MexicoMartínez-Cruz Perla Mónica, Nakamura-López Yuko, Quintero-Hernández Verónica et al.Mutations in target genes have been described in Mycobacterium tuberculosis Complex (MTBc) drug resistant isolates worldwide. In Mexico, not enough information has been reported in this concern. The aim of this study was to characterize mutations related to resistance to first line drugs in MTBc isolates from Oaxaca, Mexico. MTBc isolates were identified in clinical samples from Tuberculosis (TB) patients. … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 28 Oct 2021 · 6,667 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGenetic Diversity and Drug Resistance of Mycobacterium tuberculosis Complex Isolates and Nontuberculous Mycobacteria Identification from Presumptive Tuberculosis Cases in Oaxaca, MexicoNakamura-Lopez Yuko, Valencia-Carmona Oscar Daniel, Martinez-Cruz Perla Monica et al.Tuberculosis (TB) is a re-emerging health problem worldwide. In Mexico, information about genetic diversity and drug resistance of Mycobacterium Tuberculosis complex (MTBc) is limited. Samples from 463 Presumptive TB cases were tested for TB by smear, culture and PCR, from which 19.2% were identify as MTBc and 16% as nontuberculous mycobacteria. MTBc isolates were characterized by Large Sequence Polymorphisms (LSPs), … …American Journal of Infectious Diseases, Vol. 16, Issue 1 · 9 Feb 2020 · 7,159 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleStrategies of Tuberculosis–HIV Vaccines Design using Immunoinformatic ApproachAni Fatonah, Ig. Satrio Wicaksono, Usman Sumo Friend TambunanTuberculosis is amongst the highest cause death worldwide. According to WHO, an estimated of more than a million people fell ill with Tuberculosis (TB) in 2016. The resistances of the M. tuberculosis (MTb) bacteria make drugs, not that useful in battle with TB. Vaccination is a better choice to avoid the worst cases of TB. The resistance possessed by MTb … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 10 May 2019 · 7,925 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of Health Education on Tuberculosis Case-Finding Based on Advocacy, Communication and Social Mobilization (ACSM) Movement in Majene District, West Sulawesi, IndonesiaMuhammad Syafar, Muhammad Ikhsan, Indra Fajarwati Ibnu, Rachma RahimThis research aimed to determine the effect of tuberculosis (TB) active case-finding interventions based on Advocacy, communication and social mobilization (ACSM) movement toward housewives’ knowledge at the work area of Banggae I Community Health Center, Majene District, West Sulawesi, Indonesia. Quasi-experimental one group pretest and posttest design was used in this research. Participants of the research were selected by inclusive … …American Journal of Infectious Diseases, Vol. 15, Issue 1 · 6 Feb 2019 · 7,929 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEfficient Production of Glycosylated and Non-Glycosylated Mycobacterium tuberculosis Antigen 85B Fused to PVX Coat Protein in Nicotiana benthamiana PlantsPablo A. González, Franco D. Puccio, Alicia M. ZeladaThe development of alternative subunit based-vaccines against tuberculosis is necessary due to variable efficiency and some security concerns of the BCG vaccine. The aim of this work was evaluate the production of the Mycobacterium tuberculosis Ag85B antigen fused to Potato Virus X Coat Protein (PVX-CP) by transient expression in Nicotiana benthamiana for subunit-based tuberculosis vaccine formulation. A codon-optimized M. tuberculosis … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 13 Nov 2018 · 9,976 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleComparison of CART and CART ARCING to Classify Household Food Security of Tuberculosis Patients in SurabayaIis Dewi Ratih, Sri Pingit Wulandari, Bambang Widjanarko Otok, Yusnada Asa NuraniIndonesia shall fulfill the residents need of food by its heterogeneous and big resource of food. But in fact, Indonesian food security is still far from expectation because of the maintenance of food resource in Indonesia has not been maximized yet. Meanwhile, households with tuberculosis patients in Surabaya tend to classify as food-insecure. This study conduct a classification of households … …Journal of Mathematics and Statistics, Vol. 14, Issue 1 · 28 May 2018 · 7,456 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSocio-Demographic Determinants of Adult Tuberculosis: A Matched Case-Control Study in BangladeshSamira Dishti Irfan, Mohammad Omar Faruque, Mahabub Ul Islam et al.Tuberculosis (TB) is a multi-systemic infectious disease that has evoked a substantial disease burden in developing countries, including Bangladesh. The aim of this study is to determine the socio-demographic risk factors for adult tuberculosis. A matched case-control study was conducted with 178 cases and 179 controls from a selected TB hospital in Dhaka. Data was collected via face-to-face interview using … …American Journal of Infectious Diseases, Vol. 13, Issue 3 · 6 Nov 2017 · 10,452 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDesign and Synthesis of Diaminotriazines as Anti-Tuberculosis DHFR InhibitorsArundhati C Lele, Archana Raju, M.K. Ray et al.A series of novel 2,4 diamino-s-triazine was designed as potential Mycobacterium tuberculosis (Mtb) Dihydro folate reductase inhibitors. The synthesized compounds were evaluated in whole cells by employing Resazurin Microtitre Plate Assay (REMA) against Mtb H37Rv, using known DHFR inhibitors Methotrexate and Trimethoprim as standard drugs. The most active compound in the whole cell assay was selected for DHFR enzyme assay … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 14,716 accessesView PDFCite