25 results for “Temporal Changes”

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Research ArticleOpen accessIn the abstractA Mathematical Modeling Approach to Characterize Hormesis, Caloric Restriction and Toxicity in Mortality Data from Toxicity StudiesPatricia J. NeafseyThe mortality of a population reflects the combined effects of natural aging with environmental insults (e.g. toxicant exposure, caloric restriction, over feeding, infections, etc.). No single endpoint, such as carcinogenesis, completely describes toxicant-induced effects in laboratory animals. Mathematical models of mortality and time-dependent exposure to toxicants can yield indices of net injury from all causes. With careful manipulation of diet … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,160 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordSpatial-Temporal Variation and Topographic Effect of Vegetation Cover in Lvliang Mountains AreaHuixia Zhang, Yujie Li, Yongmei Li, Na ZhangVegetation cover is an important ecological climate parameter and to a certain extent, it indicates the change in the regional ecological environment. To explore the impact of different terrain factors on the vegetation cover in the Lvliang mountains area and the change and improvement of vegetation cover in this area. MODIS NDVI data from 2010 to 2019 were selected to … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 14 Dec 2022 · 5,104 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordClimate Projections of Future Extreme Events in MalaysiaA.H. Syafrina, M.D. Zalina, A. NorzaidaIn Malaysia, extreme rainfall events are often linked to a number of environmental disasters such as landslides, monsoonal and flash floods. In response to the negative impacts of such disaster, studies assessing the changes and projections of extreme rainfall are vital in order to gather climate change information for better management of hydrological processes. This study investigates the changes and … …American Journal of Applied Sciences, Vol. 14, Issue 3 · 21 Mar 2017 · 8,253 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordHistorical Changes in Polychlorinated Biphenyls Contaminated SedimentsViet D. Dang, David M. Walters, Cindy M. LeeProblem statement: PCBs contamination continues to pose a health risk to aquatic environments due to their recalcitrance and bioaccumulation. The Sangamo Weston/Twelvemile Creek/Lake Hartwell Superfund Site is an example of such a health risk as a result of PCBs discharged from a former capacitor manufacturing plant. We conducted a study in twelvemile creek (Clemson, SC, USA) to examine the temporal … …American Journal of Environmental Sciences, Vol. 8, Issue 1 · 25 Jan 2012 · 7,077 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordCryptolepine Provokes Changes in the Expression of Cell Cycle Proteins in Growing CellsCharles Ansah, Nigel J. GooderhamProblem statement: Cryptolepine, the antimalarial plant alkaloid is cytotoxic to mammalian cells, but there is rather little understanding of the possible mechanisms involved in the cell-kill action of cryptolepine. Approach: We examined mammalian cells exposed to cryptolepine (0.5-5.0 μM) for effects on the cell cycle and associated alterations in the levels of major regulatory proteins using immunoblotting and flow cytometry. … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,396 accessesView PDF Cite