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Research ArticleOpen accessEvery word in the titleMultivariate Analysis of Gestational Diabetes Risk Factors in a North African Population: A Call for Targeted Maternal Health InterventionsHafssa Abdellaoui, Nadia Ouzennou, Adnane Hakem, Samia RkhaGestational Diabetes (GD) is a multifactorial condition influenced by demographic, anthropometric and obstetric determinants. Identifying predictive factors is essential to anticipate the disorder, guide prevention strategies and reduce maternal and neonatal complications. To assess the risk factors associated with GDM in pregnant women in the Marrakech-Safi region, in order to fill a gap in national data. A retrospective cross-sectional study … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 10 May 2026 · 1,531 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMulti-Satellite Custody of Moving Ground TargetsDavid SchusterMaintaining persistent custody of ground targets from Low Earth Orbit (LEO) is a key challenge in space-based surveillance and reconnaissance. Traditional rule-based tasking strategies struggle with scalability as the number of assets and targets grows. In this paper, we present a centralized Reinforcement Learning (RL) approach using Proximal Policy Optimization (PPO) to coordinate four LEO satellites tasked with tracking two … …Journal of Computer Science, Vol. 22, Issue 3 · 25 Mar 2026 · 1,575 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBiformer Attention and ASF-YOLO for Cordyceps Sinensis Target RecognitionRu Yang, Peng Wu, Zhentao QinCordyceps sinensis, a highly valued traditional Chinese medicine, faces challenges in collection due to inefficiencies in manual searching, strenuous labor, and the impact of subjective expertise. The integration of deep learning into Cordyceps sinensis identification is an unexplored area. To alleviate the manual labor and enhance the precision and speed of identifying Cordyceps sinensis, a novel detection approach that combines … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 14 Nov 2024 · 4,543 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Drug-Target Interaction Prediction Based on Supervised Probabilistic ClassificationManmohan Singh, Susheel Kumar Tiwari, G. Swapna et al.Bayesian ranking-based drug-target relationship prediction has achieved good results, but it ignores the relationship between drugs of the same target. A new method is proposed for drug-target relationship prediction based on groups by Appling Bayesian. According to the reality that drugs interacting with a specific target have similarities, a grouping strategy was introduced to make these similar drugs interact. A … …Journal of Computer Science, Vol. 19, Issue 10 · 1 Sep 2023 · 5,454 accessesView PDFCite
EditorialOpen accessEvery word in the titleFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
EditorialOpen accessEvery word in the titleNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRADIOSENSITIZATION OF CANCER STEM CELLS: TARGETING TGFβ, NOTCH OR TELOMERASE TO IMPROVE TUMOR RESPONSE O RADIOTHERAPYIgnacio Fernandez-GarciaRadiation resistant cancer stem cells are the main reason for treatment failure and tumor recurrence after cancer radiotherapy. Increasing biological evidences demonstrate that these cells possess the capacity to repair radiation induced DNA damage, protect themselves from radiation derived reactive oxygen species, survive and proliferate after several fractions of radiotherapy and finally, repopulate the heterogeneity of the tumor. Thus, targeting … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Jul 2014 · 7,459 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEfficacy of Tylosin Tartrate on Mycoplasma Infections and Eggshell Apex Abnormalities in Layer Hens Under Field ConditionsKonstantinos C. Koutoulis, George Kefalas, Niki Mouttotou et al.The aim of this report was to describe a clinical case of concurrent infection with Mycoplasma Gallisepticum (MG) and Mycoplasma Synoviae (MS) in layers, complicated with Escherichia coli and Pasteurella multocida, as well as to evaluate the efficacy of tylosin tartrate treatment (Pharmasin® 100% WSG, Huvepharma) on Mycoplasma under field conditions. A flock of 18,500 ISA Brown pullets, 21 weeks … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 20 Dec 2013 · 8,732 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSingle-Digit Inflation Targeting and Economic GrowthRichard AyisiIn recent times, most central banks have adopted inflation-targeting monetary policy approach aimed primarily to achieve single-digit inflation. Though, the literature suggest that low level of inflation promotes economic growth, the literature is silent on the threshold inflation level needed to promote growth. Studies in developing countries that seek to estimate the threshold level of inflation that promotes economic growth … …American Journal of Economics and Business Administration, Vol. 5, Issue 1 · 4 Sep 2013 · 7,364 accessesView PDFCite