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250 articles for “Proteins”
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Research ArticleOpen accessEvery word in the titleBioinformatics Analysis of Some Functional Genes and Proteins Involved in Obesity-Induced Type 2 DiabetesEhab M. Abdella, Rasha R. Ahmed, Mohamed B. Ashour et al.The incidence of type-2 diabetes is rising rapidly worldwide, mainly because of the increase in the incidence of obesity, which is an important risk factor for this condition. Both obesity and type-2 diabetes are complex genetic traits but they also share some nongenetic risk factors. Differences among individuals in their susceptibility to both these conditions probably reflect their genetic constitutions. … …Current Research in Bioinformatics, Vol. 1, Issue 2 · 6 May 2013 · 12,601 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAcute Phase Proteins, Lipid Profile and Proinflammatory Cytokines in Healthy and Bronchopneumonic Water Buffalo CalvesSabry M. El-Bahr, Wael M. EL-DeebThe aim of the present study was to evaluate the diagnostic value of Acute Phase Proteins (APP), lipid profiles and proinflammatory cytokines in healthy and bronchopneumonic water buffalo calves. Therefore, sixty water buffalo calves (9±1 month old, 175±15 kg) were divided into two equal groups, the first group represented healthy, control, calves whereas calves of the second group were affected … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 8,415 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHigh Incidence of Disorder-Promoting Amino Acids in the Amino Terminus of Mature Proteins in Bacillus subtilisGuangqiang Wang, Yining Dong, Haiqin Chen et al.Problem statement: Exported polypeptides are usually synthesized as preproteins which are composed with mature domains and the signal peptides. The foreign proteins are usually inefficiently secreted by the aid of signal peptides. Although we know that the mature protein played an important role in the protein export process, we do not know what properties of the mature domains are critical … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 2 Feb 2012 · 8,255 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDevelopment of Neighbors Atomic Coordinate Tables and Plot-Graphical Representation for Tertiary Structure in ProteinsHamed Fawareh, Jehad Q. Odeh, Nawal Al-OmoushProblem statement: Contact map prediction is an interesting method for its application in fold recognition and protein tertiary structure determination. Approach: This study developed a method to predict a protein tertiary structure from the amino acid sequence using contact map. The method showed prediction a protein in a binary space of exposure states. The approach produced several procedures to finds … …Journal of Computer Science, Vol. 6, Issue 6 · 30 Jun 2010 · 6,892 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Proteomics Analysis of Drought Stress-Responsive Proteins as Biomarker for Drought-Tolerant Sugarcane CultivarsNisachon Jangpromma, Supansa Kitthaisong, Khomsorn Lomthaisong et al.Problem statement: The prime objective in breeding selection process of drought-tolerant sugarcane is to identify the correlating marker, which could lead to rapid screening for drought-tolerant cultivars. In this study, we have reported an unknown 18-kDa protein (p18) along with other stress-inducible proteins to be highly expressed in sugarcane leaves under drought stress condition. Approach: The 2D-PAGE patterns of proteins … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 9,814 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of Salmonella enteritidis Outer Membrane Proteins and Lipopolysaccharide Profiles with the Detection of Immune Dominant ProteinsA. Maripandi, Ali A. Al-SalamahProblem statement: Salmonella infection is a serious medical and veterinary problem world-wide and causes great concern in the human health and food safety. Salmonella enteritidis outer membrane proteins and lipopolysaccharide play important role in the virulence and immunological properties of bacteria. Prophylaxis of enterobacterial infection has proven difficult to achieve. Vaccination is an effective tool for the prevention of Salmonella … …American Journal of Immunology, Vol. 6, Issue 1 · 21 Jun 2010 · 9,147 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCryptolepine Provokes Changes in the Expression of Cell Cycle Proteins in Growing CellsCharles Ansah, Nigel J. GooderhamProblem statement: Cryptolepine, the antimalarial plant alkaloid is cytotoxic to mammalian cells, but there is rather little understanding of the possible mechanisms involved in the cell-kill action of cryptolepine. Approach: We examined mammalian cells exposed to cryptolepine (0.5-5.0 μM) for effects on the cell cycle and associated alterations in the levels of major regulatory proteins using immunoblotting and flow cytometry. … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,396 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNifH: Structural and Mechanistic Similarities with Proteins Involved in Diverse Biological ProcessesSurobhi Lahiri, Lakshmi Pulakat, Nara GaviniThe NifH protein is a subunit of the nitrogenase enzyme that catalyzes the reduction of atmospheric nitrogen to ammonia. This protein contains highly conserved regions including the nucleotide binding sites, metal center ligands and the Switch I and Switch II domains. A number of proteins have structural and mechanistic similarities as well as evolutionary relationships with the NifH protein, notable … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 6,671 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Interplay between p53 and p21 Tumor Suppressor Proteins in the Transformation of Colorectal Adenoma to CarcinomaA.S. Abdulamir, R.R. Hafidh, L.K. Mahdi et al.This study was carried out for evaluating the interplay of p53, p21 and Ki-67 proteins along the colorectal adenoma-carcinoma oncogenic transformation sequel. Therefore, Fifty colorectal cancer and 14 adenoma patients were involved. The histopathological expression of p53, p21 and Ki-67 proteins was evaluated by immunohistochemistry assay. The results revealed that remarkable overexpression of p53 protein was seen in the tumorous … …American Journal of Immunology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,740 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleExpression of Thioredoxin-Fusion Proteins of α-Gliadin, γ-Gliadin and Low Molecular Weight Glutenin, from Wheat Endosperm and their Domains in EnterobacteriaClaudia G. Benitez-Cardoza, Yves Popineau, Jacques GueguenWheat seed storage proteins play a determining role in the viscoelastic properties of wheat gluten. The genes encoding α-gliadin, γ-gliadin and Low Molecular Weight glutenin and their N-central-repetitive and C-terminal domains from wheat endosperm had been subcloned into a thioredoxin expression system (pET102/D-Topo) and produced as fusion proteins in E. coli. The expression levels for each of the proteins varied … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 6,746 accessesView PDFCite