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31 results for “Pharmaceuticals”
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Research ArticleOpen accessIn the abstractApplication of Water-Soluble Polymers for Extraction Separation of Amino Acids of Various StructuresNadezhda Yakovlevna Mokshina, Dmitry Vladimirovich Bykovskiy, Gennadiy Valentinovich Shatalov, Oksana Anatolievna PakhomovaThis article actualizes the task of developing new methods for extraction separation of amino acids for the analysis and purification of target components in the production of food supplements, pharmaceuticals, agricultural products and cosmetics; it also presents the extraction separation results for binary mixtures of histidine, proline and methionine using water-soluble homo- and co-polimers with various molecular weight values. We … …American Journal of Applied Sciences, Vol. 12, Issue 12 · 10 Dec 2015 · 6,641 accessesView PDFCite
Review ArticleOpen accessIn the abstractSelected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume ParenteralsMohabbat UllahWater For Injections (WFI) which is the main vehicle of Large Volume Parenterals (LVPs) should be free from trace amount of genotoxic impurities. This review gives emphasis on quantification of genotoxic trace metals during qualification of WFI in LVPs manufacturing unit. According to ICH guidelines, impurities related to drug substances are classified into three main categories: Organic impurities, inorganic (elemental) … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 27 May 2015 · 7,708 accessesView PDFCite
Research ArticleOpen accessIn the abstractEVALUATING THE SENSITIVITY OF PSEUDOMONAS AERUGINOSA, ESCHERICHIA COLI AND SALMONELLA TYPHI TO VARIOUS BRANDS OF AMPICILLIN AND AMOXICILLIN AVAILABLE IN NIGERIAE. E. Anomohanran, U. B. Owhe-Ureghe, D. A. EhwariemeThe failure of antimicrobial agents in the treatment of some ailments has become a great concern to health care practitioners. This could be as a result of low quality drugs, sneaked into the market by those who fake them, thus, this study was carried out to evaluate the sensitivity of various brands of Amoxicillin and Ampicillin on clinical isolates of … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 4 · 22 Oct 2014 · 8,206 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Quantum Mechanical Study of Structural and Electronic Dilution Effects in Paramagnetic Chemical Exchange Saturation Transfer AgentsWhelton A. Miller III, Preston B. MooreWe present a computational study of the effect of chemical modifications of the meta and para substituents in the coordinating pendant arm of a modified 1,4,7,10-tetraazacyclododecane-N, N’, N’’, N’’’-tetraamide (DOTAM) ligand on the Chemical Exchange Saturation Transfer (CEST) signal. Magnetic Resonance Imaging (MRI) is currently one of the most widely used techniques available. MRI has led to a new class … …Journal of Organic and Biomolecular Simulations, Vol. 1, Issue 1 · 11 Dec 2013 · 28,364 accessesView PDFCite
Research ArticleOpen accessIn the abstractToxicity evaluation of yoyo 'cleanser' bitters and fields Swedish bitters herbal preparations following sub-chronic administration in ratsMartins Ekor, Odusoga Adewale Osonuga, Adesina Olalekan Odewabi et al.Problem statement: Owing to numerous adverse effects of most orthodox pharmaceuticals, the use of herbal remedies in treatment and prevention of diseases is gaining much attention, especially in developing countries. The increase patronage of these remedies is often predicated on the assumption that they are harmless since they are prepared from natural sources. However, toxicity related to herbal medicines is … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 10,198 accessesView PDFCite
Research ArticleOpen accessIn the abstractExtraction and Purification of Collagenase Enzymes: A Critical ReviewSaid M Daboor, Suzanne M Budge, Abdel E Ghaly et al.Problem statement: Enzymes have vital roles in several industrial processes (foods, cosmetics, nutraceuticals and pharmaceuticals) due to their highly selective nature and high activity at very low concentrations. Recent efforts to identify new sources of useful enzymes have been concentrated on the marine environment because of the potential to make use of processing wastes. About 35-50% of the mass of … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 4 · 31 Dec 2010 · 14,311 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn the Hormetic Behaviour of Drugs Binding to Different Redox States of Amine Oxidase EnzymesDeepak Narang, G. Reid McDonald, David J. Smith et al.Classical monoamine oxidases and copper-containing semicarbazide-sensitive amine oxidases are drug targets for a variety of established and novel pharmaceuticals used to treat conditions such as depression, Parkinsonism and inflammatory disorders. Development of enzyme inhibitors, both historically and currently, assumes an underlying adherence of these enzymes to Michaelis-Menten kinetic principles. In this mini-review, we discuss historical data from several laboratories and … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 6,928 accessesView PDFCite