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72 articles for “Oral Administration”
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Research ArticleOpen accessIn the abstractSelenium and Cadmium Tissue Concentrations and the CASA Sperm Motility Analysis after Administration to RatsRobert Toman, Svatoslav Hluchy, Peter Massanyi et al.The accumulation of Selenium (Se) and Cadmium (Cd) and their effects on sperm motility parameters in rats were investigated. Male rats were dosed with Cd (group A: 2 mg kg-1 b.w., intraperitoneally, group B: 30 mg L-1, per os in drinking water) and Se (group D: 2 mg kg-1 b.w., intraperitoneally, group E: 5 mg L-1, per os in drinking … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 13 Dec 2014 · 7,979 accessesView PDFCite
Research ArticleOpen accessIn the abstractCHITOSAN NANOPARTICLES AND THEIR APPLICATIONS IN DRUG DELIVERY: A REVIEWSharare Najafi, Zahra Pazhouhnia, Omid Ahmadi et al.Chitosan is one of the most popular materials in the field of drug delivery due to its adhesivity and biodegradability. Different types of Chitosan based drug carriers have been conceived for various administration routes, such as oral, nasal, transdermal, parenteral, vaginal, cervical and rectal due to its biocompatibility and biodegradability. Chitosan Nanoparticles (NPs) have long been studied as carriers for … …Current Research in Drug Discovery, Vol. 1, Issue 1 · 8 Nov 2014 · 14,775 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECTS STUDY OF NIGELLA SATIVA, ITS OIL AND THEIR COMBINATION WITH VITAMIN E ON OXIDATIVE STRESS IN RATSAmr A. RezqAntioxidants or free radical scavengers are very important in protecting the living cells against any damage induced by free radicals. The effects of Nigella Sativa Extract (NSE), Nigella Sativa Oil (NSO) and Vitamin E (Vit. E) and the combination of NSE or NSO with Vit. E on potassium bromate (KBrO3)-induced oxidative stress in male rats were investigated. Forty nine Sprague … …American Journal of Applied Sciences, Vol. 11, Issue 7 · 23 Apr 2014 · 7,005 accessesView PDFCite
Research ArticleOpen accessIn the abstractABSENCE OF VISIBLE TOXIC EFFECTS ACCOMPANYING THE SHORT-TERM ADMINISTRATION OF AN AQUEOUS EXTRACT OF ALLIUM SATIVA LINN. IN MALE SPRAGUE-DAWLEY RATSJ. Asiedu-Gyekye Isaac, Awortwe Charles, A. Antwi DanielAllium sativum is cultivated in the northern part of Ghana and has gained widespread use as chemoprotective, in curing hypertension, impotence and erectile dysfunction. The multipurpose use together with its aphrodisiac activity has resulted in the widespread use of this plant medicine both in meals and as herbal medications. Safety assessment of this plant however is rare. The present study … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 30 Jan 2014 · 7,577 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Chromium(VI) on Serum Iron and Removal of its Toxicity by Combining Deferasirox and Deferiprone Chelators in RatsS. Jamil A. Fatemi, Marzieh Iranmanesh, Faezeh Dahooee BaloochThe present research is aimed to characterize the potential efficiency of two chelators after chromium(VI) administration for 60 days following two doses of 15 and 30 mg kg-1 chromium(VI) per body weight daily to male rats. However, the hypothesis that the two chelators might be more efficient as combined therapy than as single therapy in removing chromium(VI) from bood serum … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 30 Oct 2013 · 7,152 accessesView PDFCite
Research ArticleOpen accessIn the abstractAcute Phase Protein Responses in Mice Infected with River Water Contaminated by Pasteurella multocida Type B: 2Mohammed Muqdad Khaleel, Faez Firdaus Jesse Abdullah, Lawan Adamu et al.Animals are predisposed to infections through varieties of ways which activate the innate immune systems at the initial phase of acute infections. Hemorrhagic Septicemia (HS) is a devastating septicemic disease of cattle and buffaloes caused by a particular serotypes of Pasteurella multocida and serotype B: 2 is the most importanta cause of the disease in Asia. Therefore, the present study … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 17 Sep 2013 · 7,756 accessesView PDFCite
Research ArticleOpen accessIn the abstractNiacin Ameliorates Hypercalciuria and Hyperphosphaturia Due to Glucocorticoid Administration in RatsTahoora Shomali, Ali FakhrzadHypercalciuria and hyperphosphaturia are present in long term and high dose regimens of glucocorticoid therapy. This study aims to evaluate the effect of niacin at its pharmacological dose on calcium and phosphate disturbances due to methylprednisolone administration in growing rats. Twenty one rats were randomly divided into three equal groups and treated as follows for 4 weeks: 1-Normal saline (Control); … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 13 Jul 2013 · 7,404 accessesView PDFCite
Research ArticleOpen accessIn the abstractPossible Therapeutic Role of Jasonia Candicans and Jasonia Montana Extracts in the Regression of Alzheimer’s Disease in Experimental ModelHanaa H. Ahmed, Hoda F. Booles, Wagdy K.B. Khalil et al.The present article aimed to investigate the potential role of the ethanolic extracts of the aerial parts of Jasonia candicans and Jasonia montana in management of Alzheimer’s Disease (AD) in experimental model. Supplementation of drinking water AlCl3 (0.3%) for 16 weeks induced AD in male rats with siginifcant increase in brain Acetylcholinesterase (AchE) activity, Tumour Necrosis Factor (TNF-α), Transforming Growth … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 7,830 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Venom Studies on Olax viridis and Syzygium guineense ExtractsOmale James, Ebiloma Unekwuojo Godwin, Ogohi Dorathy AgahOlax viridis (Olacaceae) and Syzygium guineense (Myrtaceae) are shrubs commonly found in the tropics. They are traditional folkloric medicine for a great number of sicknesses. Olax viridis has a wide range of applications in ethnomedicine which include treatment for ulcers, veneral diseases, ringworm, sleeping sickness, diarrhea, fever. Syzygium guineense has been reported as antidiarrheal agent. Liquid from the bark and … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 12 Apr 2013 · 8,207 accessesView PDFCite
Research ArticleOpen accessIn the abstractResidues Depletion Study and Withdrawal Period Determination of Sulphadiazine and Trimethoprim Premix in PigsPanagiotis Dimitrios Katsoulos, Lydia Dritsa, Georgios Christodoulopoulos et al.The emergence and spread of antibiotic resistant human pathogens have been directly linked to the use of antibiotics in livestock production. The purpose of this study was to detect and quantify the concentration of the residues of Sulphadiazine (SDZ) and Trimethoprim (TMP) in edible tissues of pigs and to determine the withdrawal period after oral administration of OPTIPRIME® premix 40%, … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 12 Feb 2013 · 8,360 accessesView PDFCite