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27 articles for “Mutagen”
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Research ArticleOpen accessIn the abstractVariability of Chloroplast DNA of Extranuclear Sunflower MutantsMarkin Nicolay, Aieksandr Usatov, Maria Logacheva et al.A comparative analysis of full-genome sequences of chloroplast DNA (cpDNA) of the original inbred line 3629 and three extranuclear mutants, which were obtained by the method of mutagenesis induced with N-nitroso-N-methylurea (NMU) and characterized by different level of chlorophyll insufficiency (en:chlorina-7-yellow-green leaves; chlorophyll content (a + b)-67.8% with respect to the line 3629, variegated-10-leaves with white zones; chlorophyll content (a … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 1 · 26 Mar 2016 · 7,269 accessesView PDFCite
EditorialOpen accessIn the abstractCommentary-How do we Improve Training for Receptor Research?Marilee Ann BenoreThis issue of the American Journal of Biochemistry and Biotechnology features articles about receptor-ligand interactions that are critical to the wellbeing of all living organisms. The importance of the field of receptor research is supported by the large number of articles published in journals, the numerous specialty journals, the international conferences and the percentage of legal drugs on the market … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 8 Dec 2015 · 8,056 accessesView PDFCite
Review ArticleOpen accessIn the abstractSelected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume ParenteralsMohabbat UllahWater For Injections (WFI) which is the main vehicle of Large Volume Parenterals (LVPs) should be free from trace amount of genotoxic impurities. This review gives emphasis on quantification of genotoxic trace metals during qualification of WFI in LVPs manufacturing unit. According to ICH guidelines, impurities related to drug substances are classified into three main categories: Organic impurities, inorganic (elemental) … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 27 May 2015 · 7,708 accessesView PDFCite
Research ArticleOpen accessIn the abstractConstitutive Androstane Receptor Dependent and Independent Modulation of CYP3A2, CYP1A2 by Phenobarbital and Fibrate in Rats’ LiverMohamed Mohamed Ahmed, Mustafa Shukry, Zein Shaban Ibrahim et al.Cytochrome P450 enzymes, CYP3A and CYP1A are major drug metabolizing enzymes in the liver. CYP3A enzymes have a major role in the metabolism of 30-40% of all used drugs. CYP1A2 is a key enzyme having an important role in the metabolic clearance of 5% of currently marketed drugs. CYP1A2 participates in the metabolic activation of chemical mutagens in cooked food, … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,381 accessesView PDFCite
Research ArticleOpen accessIn the abstractDecolorization of Mordant Orange-1 by Marinobacter algicola MO-17R. S. Shertate, Prakash ThoratProblem statement: The textile industries use different types of dyes in their processing units which are liberated in natural marine water bodies. This release of dyes in turn affect the marine flora and fauna very adversely. Approach: The release of textile dyes into the environment is a matter of concern due to the toxicity, mutagenicity, carcinogenicity and xenobiotic nature. Hence, … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 25 Feb 2012 · 7,513 accessesView PDFCite
Research ArticleOpen accessIn the abstractTartaric Acid Modified Rice Hull as a Sorbent for Methylene Blue RemovalSiew-Teng Ong, Pei-Sin Keng, Ai-Wen Chong et al.Problem statement: Improper dye discharge from various industries such as textile, paper, cosmetic and plastics into receiving streams can be one of the sources towards water pollution. The release of these effluents not only causes various disruptions in the ecosystems, but also poses hazard effect as most of the dyes are highly toxic, mutagenic and carcinogenic in nature. Approach: To … …American Journal of Environmental Sciences, Vol. 6, Issue 3 · 30 Jun 2010 · 7,151 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiscretization Numerical Data for Relational Data with One-to-Many RelationsRayner AlfredProblem statement: Handling numerical data stored in a relational database has been performed differently from handling those numerical data stored in a single table due to the multiple occurrences (one-to-many association) of an individual record in the non-target table and non-determinate relations between tables. Numbers in Multi-Relational Data Mining (MRDM) were often discretized, after considering the schema of the relational … …Journal of Computer Science, Vol. 5, Issue 7 · 31 Jul 2009 · 7,030 accessesView PDFCite