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47 results for “Induced resistance”
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Research ArticleOpen accessIn the abstractAdiponectin Regulation in Type 2 Diabetic Rats: Effects of Insulin, Metformin and DexamethasoneTamer Ahmed Ismail, Mohamed Mohamed Soliman, Shimaa Ahmed IsmailAdiponectin is a protein synthesized from adipose tissue, increases peripheral glucose utilization in liver and skeletal muscle. Adiponectin expression and secretion are decreased during obesity and insulin resistance. In this study, the effect of insulin, metformin and dexamethasone on serum lipid profiles was examined in Type 2 Diabetic (T2D) rats. T2D was induced by feeding rats a high fat diet … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 23 Nov 2013 · 7,723 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntiretroviral Toxicity and Oxidative StressAdikwu Elias, Brambaifa Nelson, Deo Oputiri, Oru-Bo Precious GeoffreyAntiretroviral drugs are used for the treatment of human immunodeficiency virus, they are used as combination regimens to achieve the highest possible benefit, tolerability, compliance and to diminish the risk of resistance development. Reports from preclinical and clinical studies have linked antiretrovirals with some toxicological effects which could be associated with redox imbalance (oxidative stress). This stimulated us to review … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 20 Nov 2013 · 8,255 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdaptogenic Potentials of Cyphostemma glaucophilla Aqueous Leaf ExtractOjogbane Eleojo, Nwodo Okwesili Fred Chiletugo, Omale JamesCytophostemma glaucophilla aqueous extract is used in Kogi and Kwara States of Nigeria to treat Kwashiorkor and to boost immunity. As part of the effort to evaluate its effect on stress, it was screened for adaptogenic potentials. This investigation was conducted using albino rats to determine the ability of this plant to increase non specific resistance against physical, biological and … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 7,118 accessesView PDFCite
Research ArticleOpen accessIn the abstractMelanoma-Associated Suppression of the Dendritic Cell Lines DC2.4 and JawsiiKristian Michael Hargadon, Yonathan Tarekegne Ararso, Osric Anthony Forrest, Chad Mason HarteDendritic cells function as potent regulators of both innate and adaptive immunity to tumors and the regulatory activities of these cells are tightly linked to their maturation and activation status. Despite the critical role played by dendritic cells in the induction of anti-tumor immune responses, the number of dendritic cells that can be isolated from experimental animals is limiting and … …American Journal of Immunology, Vol. 8, Issue 4 · 3 Nov 2012 · 9,559 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuercetin in Dimethyl Benzanthracene Induced Breast Cancer in RatsNatla Sashidhar Reddy, Parthasarathy Nirmala, Natesan Chidambaram, Pammi Ashok kumarProblem statement: Vincristine a commonly used anticancer agent in the treatment of breast cancer results in serious adverse effects like teratogenicity, neurotoxicity and carcinogenicity on long term use. Drug resistance is also a common problem encountered with vincristine. Hence the effect of flavonol quercetin, a known antioxidant with no known documented adverse effect was tried in treatment of DMBA induced … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 30 Jul 2012 · 8,138 accessesView PDFCite
Research ArticleOpen accessIn the abstractSoil Compaction in Sugarcane Fields Induced by MechanizationPrathuang Usaborisut, Watcharachan SukcharoenvipharatProblem statement: Recently in Thailand, the problem of soil compaction, especially associated with more mechanized sugarcane production, has drawn attention from both the government and private sectors. Approach: To understand this problem, investigations of soil compaction using cone penetration resistance and bulk density were conducted in 16 sugarcane fields with 10 fields involving mechanized farming and 6 field's mainly manual … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 3 · 14 Sep 2011 · 8,404 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvestigation of Abutment Displacement of a Full Height Integral Bridges in Dense Granule BackfillM. H. Alizadeh, A.R. Khalim Rashid, Zamri Chik, S. M. MirhosseinyProblem statement: In this study, the behavior of abutment wall in full height frame integral abutment bridges was investigated. It was seen that the effect of backfill soil resistance on behavior of abutment wall movement is mostly neglected in previous studies. In this research, the final bridge superstructure displacement under temperature-induced forces was formulated. In addition, according to the final … …American Journal of Engineering and Applied Sciences, Vol. 3, Issue 4 · 30 Nov 2010 · 8,352 accessesView PDFCite
Research ArticleOpen accessIn the abstractEndothelial Dysfunction and Insulin Resistance as Pathophysiologic Mechanisms in a Rat Model of PreeclampsiaAyman Z. Elsamanoudy, Amr M. AbbasProblem statement: To assess the plasma concentrations and placental gene expression of soluble fms like tyrosine kinase (sFlt-1), Vascular Endothelial Growth Factor (VEGF), visfatin and Tumour Necrosis Factor α (TNFα) in a rat model of preeclampsia, induced by chronic Reduction of Uterine Perfusion Pressure (RUPP) and to investigate the involvement of Insulin Resistance (IR) in the pathophysiology of preeclampsia and … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 7,503 accessesView PDFCite
Research ArticleOpen accessIn the abstractDo Resistin and Tumor Necrosis Factor-α Relate to Changes in Insulin Resistance in Normal Pregnancy?Parvin Zareian, Abdolreza Sotoodeh Jahromi, Fateme Hemati Rad, Safar ZareiProblem statement: The purpose of this study was to evaluate the role of resistin and Tumor Necrosis Factor-α (TNF-α) in insulin resistance during pregnancy. Approach: Serum resistin and TNF-α concentrations were measured by ELISA in 86 healthy pregnant women (26, 23 and 37 of them in the 1st, 2nd and 3rd trimesters, respectively) and in 21 healthy non pregnant women … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 7,810 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Capability of Young Layers for Survival after Salmonella entritidis ChallengeE. S. Soliman, H. Busby, C. Kilpatrick et al.Problem statement: Genetic line differences in resistance of layer hens and young chicks to Salmonella entritidis have been identified through a lot of studies. That is why the agricultural industry was prepared for the potential phasing out of antibiotics for use in controlling bacterial pathogens. Early infection may result in long term colonization of layers with Salmonella entritidis, resulting in … …American Journal of Applied Sciences, Vol. 6, Issue 10 · 31 Oct 2009 · 6,780 accessesView PDFCite