25 articles for “Binding Energy”

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Research ArticleOpen accessIn the abstractPolymorphism of Insulin-Like Growth Factor 1 Gene in Najdi Cattle PopulationsAhmad Yazdanpanah, Khalil Mirzadeh, Morteza Mamouei et al.The Insulin-like Growth Factor 1 (IGF-1) system plays a critical endocrine role controlling nutrient metabolism in dairy cattle and it is a group of structurally-related polypeptides that regulate the growth of many types of mammalian cells. In liver, IGF-1 is dynamically regulated by lactation and energy balance. Less is known about the regulation of IGF-1 and IGF-binding protein mRNA in … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,154 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBioactive Compounds Screening from Zingiberaceae Family as Influenza A/Swine Flu Virus Neuraminidase Inhibitor through Docking ApproachUsman Sumo Friend Tambunan, Fadilah, Arli Aditya ParikesitProblem statement: Influenza A/H1N1 is a disease caused by infection of influenza a virus subtype H1N1. It is a major health problem in tropical and subtropical countries. This virus constantly mutates and consequently will be developed into new drug-resistant strains. Approach: In this research, we have conducted docking study to screen bioactive compounds from Zingiberaceae family, which has a role … …OnLine Journal of Biological Sciences, Vol. 10, Issue 4 · 31 Dec 2010 · 8,616 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPriority and Random Selection for Dynamic Window Secured Implicit Geographic Routing in Wireless Sensor NetworkZurina Mohd Hanapi, Mahmod Ismail, Kasmiran JumariProblem statement: Sensor nodes are easily exposed to many attacks since it were deployed in unattended adversarial environment with no global addressing and used for critical applications such as battlefield surveillance and emergency response. While the sensor also needs to act as a router to relay a message to a required recipient, then this increased the vulnerabilities to a network … …American Journal of Engineering and Applied Sciences, Vol. 2, Issue 2 · 30 Jun 2009 · 7,652 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordRelation between Macroscopic Binding Constant and the Anticancer Efficacy of the Bovine Serum Albumin-Quercetin Complex against Drug-Sensitive and Drug-Resistant CellsWinit Choiprasert, Chatchanok Loetchutinat, Nathupakorn Dechsupa, Samlee MankhetkornProblem statement: We have previously analyzed the interaction of BSA with flavonoids by using FRET. In this study, the role of BSA on increasing in solubility and on carrying the quercetin derivatives thus enhanced their anticancer efficacy against drug-sensitive and drug-resistant cells were conducted. Approach: The macroscopic (KD) and microscopic (kd) binding constant of the complexation and the cellular partition … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 8,292 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordHydrophobic, Polar and Hydrogen Bonding Based Drug-Receptor Interaction of TetrahydroimidazobenzodiazepinonesV.K. Sahu, A.K.R. Khan, R.K. Singh, P.P. SinghAnti-HIV drug discovery has been increasingly focusing on HIV-1-RT (reverse transcriptase) as a potential therapeutic target. Tetrahydroimidazobenzodiazepinone (TIBO) belongs to non-nucleoside group of reverse transcriptase inhibitors (NNRTIs). A computational chemistry study has been performed on a series of tetrahydroimidazo-benzodiazepinones as HIV-1-NNRT inhibitors. Problem statement: In order to search out new drug of desired activity from the lead compounds, there was … …American Journal of Immunology, Vol. 4, Issue 3 · 30 Sep 2008 · 8,837 accessesView PDF Cite