Research ArticleOpen accessIn the abstractCharacterization of Nigella Sativa L. Essential Oil-Loaded Solid Lipid NanoparticlesNagi A. ALHaj, Mariana N. Shamsudin, Norfarrah M. Alipiah et al.Problem statement: Seeds of Nigella Sativa L., commonly known as black seed, have been used in traditional medicine by many Asian, Middle Eastern and Far Eastern Countries to treat headache, coughs, abdominal pain, diarrhea, asthma, rheumatism and other diseases. The seeds of this plant are the most extensively studied, both phytochemically and pharmacologically. The aqueous and oil extracts of the … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 17,874 accessesView PDFCite
Research ArticleOpen accessIn the abstractAtopic Dermatitis and Type 1 Diabetes Mellitus in Iranian ChildrenElham Ahmadi, Zahra Rahnama, Ali Rikhtegaran TehraniProblem statement: Atopic diseases, including asthma, eczema and allergic rhinitis, are characterized by a chronic inflammatory reaction mediated by T helper 2 cells, while type 1 diabetes mellitus is mediated by T helper 1 cells. Approach: The aim of this study was to compare the prevalence of atopic dermatitis between children with type 1 diabetes mellitus and age-matched controls. We … …American Journal of Immunology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,010 accessesView PDFCite
Research ArticleOpen accessIn the abstractPharmacophore Pattern Identification of Tachykinin Receptor Selective Peptide Agonists: Implications in Receptor SelectivityAnjali Dike, Indu R. Chandrashekaran, Anil K. Mantha et al.The mammalian tachykinin (TK) peptides and their three Neurokinin (NK1, NK2 and NK3) receptors represent an effector system with wide-ranging actions on neuronal, airway smooth muscle, mucosal, endothelial, immune, inflammatory and remodeling cell function. Recent clinical and preclinical data suggests the pathophysiological role of TKs in various diseases including asthma, emesis and depression. The TK-NK receptor interactions and overlapping functions … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,691 accessesView PDFCite