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42 articles for “Aging Effect”

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Research ArticleOpen accessIn the abstractApplication of Bio-Modified Montmorillonite Clay to Enhance Asphalt Oxidation ResistanceShahrzad Hosseinnezhad, Elham H. Fini, Taher M. Abu-LebdehThis study evaluates the effectiveness of using a Bio-modified Nanoclay additive (BNC) to reduce the oxidative aging of asphalt pavements. The study results through X-Ray Diffraction analysis showed that the modification of montmorillonite clay with bio-modifier increased the basal d-spacing of clay. The resulting nanoclay with increased interlayer spacing was chosen for application in asphalt binder. Rheological characterization of clay-modified … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 31 Mar 2018 · 9,054 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Pre-Slaughter Autophagic Status on Postmortem Proteolysis in Skeletal Muscle of MiceTomonori Nakanishi, Miho Yamashita, Naoto Nishimoto et al.Post mortem proteolysis is a key event during the aging process, where muscle converts to meat. However, its precise mechanism remains unclear. In this study, the effects of pre-slaughter autophagic status on post mortem proteolysis were investigated using mouse skeletal muscle. Mice were fasted for 14 h and administered with or without the autophagy inhibitor wortmannin, whereas control mice were … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 2 · 10 Jul 2017 · 7,988 accessesView PDFCite
Review ArticleOpen accessIn the abstractMicroRNA-92a: The Administrator of Certain DiseasesZhiyuan Sun, Qing Xu, Xiaoyi Tian et al.MicroRNA-92a (miR-92a) is an evolutionarily conserved noncoding small RNA that can regulate gene expression after transcription. Previous studies have found that miR-92a is overexpressed in many tumors and can regulate numerous tumor suppressor genes negatively, with relevant effects on the development of different tumors, by regulating the DUSP10/c-Jun N-terminal kinase (JNK), phosphatase and tensin homologs (PTEN)/AKT, Wnt and EP4/Notch1 signaling … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 21 May 2020 · 6,494 accessesView PDFCite
Research ArticleOpen accessIn the abstractFactors Those Up Regulate Klotho and Glutathione Peroxidase-1 Gene Expression Improve Renal Function in Rats with Acute Renal FailureFatma E. El-Gendey, Shabaan A. Hemeda, Gamal A. Sosa, Naglaa F. AlhusseiniAcute Renal Failure (ARF) has traditionally been defined as the abrupt and progressive loss of kidney functions resulting in the retention of urea and other nitrogenous waste products associated with interstitial inflammation, tubular injury and increasing Tumor Necrosis Factor (TNF). Mortality in patients with ARF remains high >50% in severely ill patients. Klotho gene is a new anti-aging gene. Genetic … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 15 Aug 2015 · 7,097 accessesView PDFCite
Research ArticleOpen accessIn the abstractCritical Aging Segments of Power Transmission LineH. H. Goh, N. E. Chin, Q. S. Chua et al.Nowadays, blackouts or sags of a conductor are threatening the safety and stable run of the power transmission lines. These phenomena happen due to the environmental conditions which change over the time, such as aging or temperature variations, precipitation and hotspots of power transmission lines as a result of extreme weather conditions. A precipitation condition result loses of heat from … …American Journal of Engineering and Applied Sciences, Vol. 6, Issue 4 · 9 Dec 2013 · 9,264 accessesView PDFCite
Research ArticleOpen accessIn the abstractAphrodisiac Activity of Kaempferia parvifloraJintanaporn Wattanathorn, Prasert Pangphukiew, Supaporn Muchimapura et al.Problem statement: The increasing prevalence of sexual dysfunction and the limitation of therapeutic efficacy nowadays give rise to the requirement of novel therapeutic strategy. Kaempferia parviflora or Krachai-Dun has been long term used in Thai traditional folklore to treat this condition. Unfortunately, no scientific document is available until now. Therefore, this study was undertaken to determine the effect of this … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 2 · 9 Mar 2012 · 10,476 accessesView PDFCite
Research ArticleOpen accessIn the abstractDegradation of High Voltage Polymeric Insulators in Arid Desert's Simulated Environmental ConditionsYasin KhanProblem statement: High Voltage (HV) polymeric insulators are replacing ceramic insulator commonly used for HV outdoor networks due to their ease of handling, reliability and cost. However, their long term performance and reliability are major concerns to power utilities. Approach: To investigate their performance in arid desert's conditions, two types of HV composite insulators were aged as per International Electrochemical … …American Journal of Engineering and Applied Sciences, Vol. 2, Issue 2 · 30 Jun 2009 · 8,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractProgressive Resistance Training on Elderly HIV+ Patients: Does it Work?Paula Maria Loiola De Souza, Wilson Jacob Filho, José Maria Santarém et al.Elderly people present significant alterations on body composition and physical fitness, compromising their quality of life. Chronic diseases, including HIV/AIDS, worsen this situation by increasing aging effects on body composition and muscle strength. Resistance exercises are prescribed by major health organizations for improving fitness and promoting a shift towards a healthier and more independent aging. In addition, recovering strength and … …American Journal of Infectious Diseases, Vol. 4, Issue 4 · 31 Dec 2008 · 6,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic Interventions in AgingSuresh I.S. RattanSingle or multiple exposure to low doses of potentially harmful agents can have a variety of anti-aging and longevity-extending hormetic effects. These hormetic stressors include irradiation, physical activity, food limitation, heat, hypergravity, dietary components and reactive oxygen species. Molecular mechanisms facilitating the hormetic effects are being elucidated and comprise a cascade of stress response and maintenance and repair pathways. Although … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,831 accessesView PDFCite
Research ArticleOpen accessIn the abstractLife Extension by Anti-Aging Drugs: Hormetic Explanation?A.M. VaisermanA number of chemicals including antioxidants, vitamins and hormones are widely advertised as anti-aging drugs (geroprotectors). It is usually believed that life-extending capacity of geroprotectors may be attributed to their specific anti-aging mechanisms, even without solid scientific evidence. The analysis of the survival data gathered by both anti-aging and hormetic interventions demonstrates that many essential similarities exist between them. The … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 8,162 accessesView PDFCite