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28 articles for “Acute Stress”
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Research ArticleOpen accessIn the abstractAroclor 1254 Toxicity to Mice Liver Membrane AtpasesShweta Pathak, Rahul KunduPresent communication reports the sub-acute dose and exposure duration dependent effects of Aroclor 1254 on total, Na+, K+, Ca++ and Mg++-ATPases of the mouse liver cells. The study tests two hypotheses, (a) whether the sublethal dose or the exposure duration dependent in vivo exposure of hydrophobic PCB (Aroclor 1254) affects the hydrophilic membrane-bound ion dependent ATPases of the liver cells … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 13 Jul 2013 · 6,795 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa Oleifera Leaves Extract Attenuates Male Sexual DysfunctionWipawee Thukhammee, Supaporn Muchimapura, Sitthichai Iamsa-ard et al.Problem statement: At present, the novel agent that is effective, cheap and easy to approach for treating male sexual dysfunction is required due to the current poor therapeutic efficacy. Though Moringa oleifera is reputed for aphrodisiac activity in traditional folklore, no scientific evidence is available. Therefore, we aimed to determine the effect of M.oleifera leaves extract on male sexual behaviors … …Neuroscience International, Vol. 3, Issue 1 · 1 Sep 2012 · 32,907 accessesView PDFCite
Research ArticleOpen accessIn the abstractDihydrobiopterin (BH2): Key Determinant in Influencing Arginine Mediated Endothelial Tolerance and DysfunctionSrinidi Mohan, Harsh Patel, Jorge Bolinaga et al.The redox-sensitive tetrahydrobiopterin (BH4) is an essential cofactor that is required by endothelial Nitric Oxide Synthase (eNOS) for L-arginine (ARG) mediated Nitric Oxide (NO) generation. Oxidation of BH4 causes cofactor insufficiency and uncoupling of eNOS, resulting in product switching from NO to O2⋅– production. Here we tested the hypothesis that eNOS uncoupling is not simply a consequence of BH4 insufficiency, … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,354 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Prophylactic and Therapeutic Effects of Silymarin on Diazepam-Induced Hepatotoxicity in CatsBahman Mosallanejad, Reza Avizeh, Hossien NajafzadehProblem statement: Diazepam is commonly administered for seizure control and appetite stimulant in cats. Cats may develop acute fatal hepatic necrosis after receiving oral diazepam for several days. The aim of this study was to detect the protective action of silymarin on diazepam-induced hepatotoxicity in cats. Approach: About 25 healthy cats were randomly allotted to five equal groups. Animals in … …American Journal of Applied Sciences, Vol. 8, Issue 9 · 29 Jul 2011 · 7,430 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction and Roles of Glial Tissue Inhibitor of Metalloproteinases-1 in Human Immunodeficiency Virus-1-Associated Dementia Neuroinflammation: A ReviewC. Chao, A. GhorpadeProblem statement: Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) and its cognate targets, the Matrix Metalloproteinases (MMPs), were differentially expressed in human brain samples with or without HIV-1 infection or HIV-1 Encephalitis (HIVE). Approach: A through literature review demonstrated that cell culture models of Central Nervous System (CNS) cell types had been used to illustrate the intricate temporal patterns of TIMP-1/MMP expression, … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 6,957 accessesView PDFCite
Research ArticleOpen accessIn the abstractImportance of blood gas measurements in perinatal asphyxia and alternatives to restore the acid base balance status to improve the newborn performanceH. Orozco-Gregorio, D. Mota-Rojas, M. Alonso-Spilsbury et al.Prolonged or intermittent asphyxia in utero and during farrowing weakens piglets and renders them less capable of adaptation to extrauterine life. Piglets with lesser viability at birth have increased blood pCO2 and blood lactic acid concentrations and decreased blood pH. Moreover, the ability to thermoregulate during an acute cold stress is inversely related to umbilical blood lactate concentrations. Blood gas … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 7,636 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordIn-Vivo Evaluation of Hexavalent Chromium Induced DNA Damage by Alkaline Comet Assay and Oxidative Stress in Catla catlaKantha Deivi Arunachalam, Sathesh Kumar Annamalai, Jaya Krishna KuruvaIn the present study, the acute toxicity of Chromium in fingerlings of Catla catla, an Indian major carp, was evaluated with renewal bioassay method. In vivo studies were designed to assess the extent of Micronucleus Assay, Comet Assay under the exposure of common heavy-metal compounds, namely, Chromium Nitrate, using Catla catla (2n = 20), as a test model. The laboratory … …American Journal of Environmental Sciences, Vol. 9, Issue 6 · 15 Jan 2014 · 7,200 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordThe "Forgotten Side Effect" of ThiazidesArnon BlumProblem statement: Thiazide diuretics are derived from benzodiazines. They inhibit Na+/Cl- re-absorption from the distal convoluted tubules in the kidneys by blocking the thiazide-sensitive Na+/Cl- symporter. They are recommended as first line treatment for hypertension in the US (JNC VII)[1] guidelines and in the National Institute of Health and Clinical Excellence/British Hypertension Society guidelines[2] and in the European (ESC/ESH)[3] guidelines. … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 8,339 accessesView PDFCite