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30 results for “Acetylcholine”
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Research ArticleOpen accessIn the abstractUnveiling the Potential of Dombeya buettneri K.Schum As a Drug Agent: Molecular Docking of Compounds With Enzymes Linked to Diabetes and Neurodegenerative DiseaseEsther Emem Nwanna, Samuel Chima Ugbaja et al.This study investigated the mechanisms of Dombeya buettneri (snowball leafy) extracts on diabetes, hypertension, and neurodegenerative diseases. It compared extracts obtained using steep water (a by-product of corn wet milling) and aqueous water. The extracts were analyzed for total phenol, total flavonoid content, antioxidant activities such as FRAP, ABTS, NO, DPPH, iron-induced lipid peroxidation assay, degradation of deoxyribose (Fenton’s reaction), … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 1 Feb 2026 · 2,025 accessesView PDFCite
Research ArticleOpen accessIn the abstractNon-Target Inhibition of Antioxidant Enzymes in Honey Bees (A. mellifera and A. florea) Upon Pesticide ExposureAmal Ahmed Berjawi, Syed Salman Ashraf, Mohammad Ali Al-DeebUnderstanding how different insecticides influence bee health is very essential. The aim of this work was to evaluate enzyme kinetics and inhibition by insecticides in Apis mellifera and Apis florea. Tested enzymes showed variable affinity to substrates. In A. florea, glutathione S-transferase (GST) showed significantly higher affinity for its 1-Chloro-2,4-Dinitrobenzene (CDNB) substrate than in A. mellifera. Carbosulfan caused the highest … …OnLine Journal of Biological Sciences, Vol. 20, Issue 2 · 10 Apr 2020 · 7,394 accessesView PDFCite
Research ArticleOpen accessIn the abstractPolycyclic Aromatic Hydrocarbon Accumulation and Biomarker Responses in Cockles from Moroccan Mediterranean CoastsIkram Chbani, Saida Bouzid, Nourredine Bouayad, Hassan Er-RaiouiThis study aims to evaluate levels and effects of Polycyclic Aromatic Hydrocarbons (PAHs) in cockles (Acanthocardia tuberculatae) collected from two differently influenced areas in the Mediterranean Western Moroccan coasts. PAHs accumulation was studied in soft tissues using Soxhlet extraction and separation on silica column methods. The measure of those organic compounds was realized by Gas chromatography coupled to Mass spectrometer … …American Journal of Environmental Sciences, Vol. 15, Issue 4 · 30 Jul 2019 · 7,497 accessesView PDFCite
Research ArticleOpen accessIn the abstractAMELIORATIVE EFFECT OF HIBISCUS SABDARIFFA LINN ON SUBCHRONIC CHLORPYRIFOS-INDUCED ALTERATIONS IN SEX AND THYROID HORMONES IN MALE WISTAR RATSShittu Muftau, Olatunji Omobolanle Aisha, Suleiman Folorunsho Ambali et al.Studies have shown that Chlorpyrifos (CPF), an Organophosphate (OP) insecticide alters both sex and thyroid hormones. Apart from inhibiting Acetylcholinesterase (AChE) activity, CPF has been shown to cause oxidative stress. The antioxidant potentials of many flavonoid-containing plants are increasingly being exploited in the therapy of many infectious and non-infectious diseases. Hibiscus Sabdariffa (HS) is one of the most widely used … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 20 Feb 2014 · 9,097 accessesView PDFCite
Research ArticleOpen accessIn the abstractPossible Therapeutic Role of Jasonia Candicans and Jasonia Montana Extracts in the Regression of Alzheimer’s Disease in Experimental ModelHanaa H. Ahmed, Hoda F. Booles, Wagdy K.B. Khalil et al.The present article aimed to investigate the potential role of the ethanolic extracts of the aerial parts of Jasonia candicans and Jasonia montana in management of Alzheimer’s Disease (AD) in experimental model. Supplementation of drinking water AlCl3 (0.3%) for 16 weeks induced AD in male rats with siginifcant increase in brain Acetylcholinesterase (AchE) activity, Tumour Necrosis Factor (TNF-α), Transforming Growth … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 7,830 accessesView PDFCite
Research ArticleOpen accessIn the abstractSilkworm Pupae Protect Against Alzheimer’s DiseaseJintanaporn Wattanathorn, Supaporn Muchimapura, Artit Boosel et al.Silkworm (Bombyx mori) pupae have long been used as food and medicine in Asian countries. It is reputed for the treatment of numerous neurological disorders related to oxidative stress including stroke. Therefore, we hypothesized that silkworm pupae could attenuate memory impairment and neurodegeneration in Alzheimer’s disease. In the present study, we determined the effect of silkworm pupae on the neurodegeneration … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 16 Aug 2012 · 9,697 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruits Protects Against Age-Related Cognitive DeclineJintanaporn Wattanathorn, Supaporn Muchimapura, Wipawee Thukhammee et al.Problem statement: The phenolic compounds and anthocyanin contents, the antioxidant and Acetylcholinesterase Inhibitor (AChI) activities of mulberry fruits were determined. Approach: Analysis of phenolic compounds and anthocyanin were performed using Folin Ciocalteu reagent and pH-differential method respectively. The antioxidant activity was determined using DPPH and FRAP assays while AChI activity was determined using Ellman method. Results: The mulberry fruit powder … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 8 Aug 2012 · 7,826 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Neuropharmacological Activities of Stephania venosa Herb Consumption in Healthy RatsTerdthai Tong-Un, Wathita Phachonpai, Supaporn Muchimapura et al.Public concern on mental health has noticeably increased given the high prevalence of neuropsychiatric disorders especially anxiety and depression. Most of the drugs for these conditions used nowadays have adverse side effects so the need for newer, better-tolerated and more efficacious treatments is remaining high. Growing attention is being paid to traditional herbal medicines. Stephania venosa Spreng (S. venosa; SV) … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 5 Jul 2012 · 7,677 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Alzheimer's Disease of Porcine Brain ExtractWipawee Thukham-Mee, Jintanaporn Wattanathorn, Supaporn Muchimapura, Chuleratana BunchonglikitkulProblem statement: Despite the increasing importance of Alzheimer’s disease, no effective therapeutic strategy is available. Therefore, neuroprotective strategy is still required. Recent findings show that numerous substances possessing antioxidant can improve neurodegeneration and memory impairment. Based on the antioxidant effect and its reputation to serve as brain tonic in traditional folklore, we hypothesized that porcine brain extract could mitigate neurodegeneration … …American Journal of Applied Sciences, Vol. 9, Issue 5 · 5 Mar 2012 · 8,243 accessesView PDFCite
Research ArticleOpen accessIn the abstractS-Allyl-Cysteines Reduce Amelioration of Aluminum Induced Toxicity in RatsSadhana ShrivastavaProblem statement: Aluminum (Al) is a trivalent cation found in its ionic form in most kinds of animal tissues and in natural waters everywhere. Approach: It is a potent neurotoxin and has been associated in the pathogenesis of several clinical disorders including Alzheimer’s disease. Results: The aim of the study was to demonstrate the protective effect of S-Allyl-Cysteines (SAC) against … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 12 Aug 2011 · 7,748 accessesView PDFCite