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302 articles for “Rats”
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Research ArticleOpen accessIn the abstractIn Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of CurcuminM. Venkata, R. Sripathy, D. Anjana et al.Problem statement: Curcumin the active component of turmeric is known for its wide biological actions. Extensive studies on curcumin highlighted its anti-inflammatory, anti-oxidant, anti-microbial, anti-carcinogenic and anti-coagulant activity. The anti-inflammatory activities of curcumin have been demonstrated both in vitro and in vivo. Though curcumin and its anti-inflammatory properties are well documented, the exact mechanism of action and effective in vivo … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 9,006 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntimicrobial and Wound Healing Potentials of Vitis Vitigenia LeavesKrishna Murti, Manish Kaushik, Aditi Kaushik, Deepika PaliwalProblem statement: The investigation for possible antimicrobial and wound healing activity of ethanolic and aqueous extracts of V. Vitigenia L. leaves were performed. The antimicrobial activity of extract was studied against the 8 bacterial and 2 fungal strains using agar cup plate method. Approach: The wound healing effect of both the extract of V. Vitigenia L. leaves were evaluated by … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,479 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Test for Two-Sample Repeated Measures Designs: Effect of High-Dimensional DataBoonyarit Choopradit, Samruam ChongcharoenProblem statement: High-dimensional repeated measures data are increasingly encountered in various areas of modern science since classical multivariate statistics, e.g,. Hotelling’s T2, are not well defined in the case of high-dimensional data. Approach: In this study, the test statistics with no specific form of covariance matrix for analyzing high-dimensional two-sample repeated measures designs with common equal covariance are proposed. The … …Journal of Mathematics and Statistics, Vol. 7, Issue 4 · 28 Oct 2011 · 7,332 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorus alba Enhanced Functional Recovery After Sciatic Nerve Crush InjurySupaporn Mucimapura, Jintanaporn Wattanathorn, Sittisak Thongrong et al.Problem statement: Traumatic nerve injury has been recognized as one of the problems commonly found in road traffic crashes. Therefore, searching for the effective substances for promoting the functional recovery of nerve after injury is in required. Accumulating lines of evidence show that free radicals generated after injury contribute the important role to retard functional recovery, thus the substance possessing … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 8,853 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Calcium Supplementation on Growth, Nutrient Digestibility and Fecal Lactobacilli in Dairy CalvesC. Yuangklang, C. Wachirapakorn, H.E. Mohamed et al.Problem statement: Based on earlier studies in veal calves and rats, the hypothesis tested was that high calcium intakes by ruminating dairy calves reduce fat digestibility, but do not affect growth performance due to enhanced colonization of the intestine with lactobacilli. Approach: In dairy calves that were fed on a combination of milk replacer, concentrate on grass hay, the effects … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 8,250 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect of Quercetin Encapsulated Liposomes: A Novel Therapeutic Strategy against Alzheimer’s DiseaseW. Phachonpai, J. Wattanathorn, S. Muchimapura et al.Problem statement: The prevalence of Alzheimer’s disease is increasing but the efficacy of treatment is still very limited due to various factors including the blood brain barrier. Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of disease. In addition the burden of blood brain barrier can be overcome by nasal administration and vesicle-carrier mediated delivery system. … …American Journal of Applied Sciences, Vol. 7, Issue 4 · 30 Apr 2010 · 9,458 accessesView PDFCite
Research ArticleOpen accessIn the abstractTaurine Implicated in Bromocriptine Induced Hallucination: Glycine-Glutamic-Aspartic Implicated in Bromocriptine Induced SchizophreniaAbdulrahim Abu JayyabProblem statement: The literature is reviewed and supports a strong anecdotal relationship between bromocriptine use and psychosis. It is well known that any interference with brain amino acid levels is likely to lead to disorder. Our previous research has shown that bromocriptine produced significant changes in the heart and kidneys amino acid contents. It has been confirmed that the brain … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 8,037 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Health and Toxic Adverse Effects of Fusarium Fungal Mycotoxin, Fumonisins, on Human PopulationW. M. Wan Norhasima, A. S. Abdulamir, F. Abu Bakar et al.Problem statements: Fumonisin was a mycotoxin produced mainly by fungi belonging to the genus Fusarium in various foods and feeds. They occurred worldwide and were found predominantly in corn and in corn-based animal feeds and also can be found in other crops. Contamination of food and feed with fumonisins has been implicated in and associated with a number of diseases … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 9,034 accessesView PDFCite
Research ArticleOpen accessIn the abstractOxidation of Exogenous Lactate by Lactate Dehydrogenase C in the Midpiece of Rat Epididymal Sperm is Essential for Motility and Oxidative ActivityHideaki Yamashiro, Masaaki Toyomizu, Akane Kadowaki et al.Problem statement: To identify the metabolic reaction-glycolysis or oxidative phosphorylation that is mainly involved in the production of energy required for rat sperm mobilization. Approach: Epididymal sperm were collected from Wistar rats and extended in lactate-containing or lactate-free raffinose-modified Krebs-Ringer Bicarbonate solution (mKRB)-egg yolk medium supplemented with 0, 1, 2, or 3 mM 2-Deoxy-D-Glucose (2 DG) and 1, 2, or … …American Journal of Applied Sciences, Vol. 6, Issue 10 · 31 Oct 2009 · 6,906 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlasma Bilirubinaemia; A Physiologic Index for Monitoring Cellular Effects of Amalar, Chloroquine, Cotecxin and FansidarE. O. Jimmy, I. F. UsohProblem statement: Antimalaria drugs are highly consumed in Africa due to increase prevalent of malaria attacks. Though the disease is often cured with some antimalarials the physiologic effects of such drugs may not be considered in pharmacologic preparations and in prescriptions. Such non consideration is likely to result in serious health problems which may outweigh the effects of malaria disease … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 7,544 accessesView PDFCite