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Research ArticleOpen accessIn the abstractPeriodic Validation of High Antidiabetic Potentials of Unripe Plantain in Comparison with Glibenclamide and FansidarE. O. Jimmy, M. A. OkonProblem statement: The antidiabetic potentials of aqueous extract of musa paradisciaca (unripe plantain fruit) were investigated in alloxan induced diabetic rats. The extract at a dosage of 120 mg kg-1 produced a significant (p<0.001) reduction in glucose level by 85% on day 7, 78% on day 14, 64% on day 21 and 44% on day 28. Approach: The extract at … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 1 · 22 Mar 2012 · 7,997 accessesView PDFCite
Research ArticleOpen accessIn the abstractCan Soy Change Serum Estradiol Concentration in Neonate Ovariectomized Rat?Mahnaz Taherianfard, Mina Tadjali, Mohammad Ebrahim AstanehProblem statement: Phytoestrogens are plant derived compound found in a wide variety of foods, most notably soy. The purpose of this study was to assess the effect of soy isoflavones on circulating 17-β estradiol in neonate ovariectomized rat. Approach: Thirty, one day olds rats were used. Blood sample were collected after two months. 17-β estradiol was assayed by radioimmuno assay … …Current Research in Medicine, Vol. 3, Issue 1 · 21 Mar 2012 · 7,402 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of CurcuminM. Venkata, R. Sripathy, D. Anjana et al.Problem statement: Curcumin the active component of turmeric is known for its wide biological actions. Extensive studies on curcumin highlighted its anti-inflammatory, anti-oxidant, anti-microbial, anti-carcinogenic and anti-coagulant activity. The anti-inflammatory activities of curcumin have been demonstrated both in vitro and in vivo. Though curcumin and its anti-inflammatory properties are well documented, the exact mechanism of action and effective in vivo … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 8,999 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntimicrobial and Wound Healing Potentials of Vitis Vitigenia LeavesKrishna Murti, Manish Kaushik, Aditi Kaushik, Deepika PaliwalProblem statement: The investigation for possible antimicrobial and wound healing activity of ethanolic and aqueous extracts of V. Vitigenia L. leaves were performed. The antimicrobial activity of extract was studied against the 8 bacterial and 2 fungal strains using agar cup plate method. Approach: The wound healing effect of both the extract of V. Vitigenia L. leaves were evaluated by … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,476 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Test for Two-Sample Repeated Measures Designs: Effect of High-Dimensional DataBoonyarit Choopradit, Samruam ChongcharoenProblem statement: High-dimensional repeated measures data are increasingly encountered in various areas of modern science since classical multivariate statistics, e.g,. Hotelling’s T2, are not well defined in the case of high-dimensional data. Approach: In this study, the test statistics with no specific form of covariance matrix for analyzing high-dimensional two-sample repeated measures designs with common equal covariance are proposed. The … …Journal of Mathematics and Statistics, Vol. 7, Issue 4 · 28 Oct 2011 · 7,328 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorus alba Enhanced Functional Recovery After Sciatic Nerve Crush InjurySupaporn Mucimapura, Jintanaporn Wattanathorn, Sittisak Thongrong et al.Problem statement: Traumatic nerve injury has been recognized as one of the problems commonly found in road traffic crashes. Therefore, searching for the effective substances for promoting the functional recovery of nerve after injury is in required. Accumulating lines of evidence show that free radicals generated after injury contribute the important role to retard functional recovery, thus the substance possessing … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 8,851 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Calcium Supplementation on Growth, Nutrient Digestibility and Fecal Lactobacilli in Dairy CalvesC. Yuangklang, C. Wachirapakorn, H.E. Mohamed et al.Problem statement: Based on earlier studies in veal calves and rats, the hypothesis tested was that high calcium intakes by ruminating dairy calves reduce fat digestibility, but do not affect growth performance due to enhanced colonization of the intestine with lactobacilli. Approach: In dairy calves that were fed on a combination of milk replacer, concentrate on grass hay, the effects … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 8,247 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect of Quercetin Encapsulated Liposomes: A Novel Therapeutic Strategy against Alzheimer’s DiseaseW. Phachonpai, J. Wattanathorn, S. Muchimapura et al.Problem statement: The prevalence of Alzheimer’s disease is increasing but the efficacy of treatment is still very limited due to various factors including the blood brain barrier. Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of disease. In addition the burden of blood brain barrier can be overcome by nasal administration and vesicle-carrier mediated delivery system. … …American Journal of Applied Sciences, Vol. 7, Issue 4 · 30 Apr 2010 · 9,449 accessesView PDFCite
Research ArticleOpen accessIn the abstractTaurine Implicated in Bromocriptine Induced Hallucination: Glycine-Glutamic-Aspartic Implicated in Bromocriptine Induced SchizophreniaAbdulrahim Abu JayyabProblem statement: The literature is reviewed and supports a strong anecdotal relationship between bromocriptine use and psychosis. It is well known that any interference with brain amino acid levels is likely to lead to disorder. Our previous research has shown that bromocriptine produced significant changes in the heart and kidneys amino acid contents. It has been confirmed that the brain … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 1 · 31 Mar 2010 · 8,032 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Health and Toxic Adverse Effects of Fusarium Fungal Mycotoxin, Fumonisins, on Human PopulationW. M. Wan Norhasima, A. S. Abdulamir, F. Abu Bakar et al.Problem statements: Fumonisin was a mycotoxin produced mainly by fungi belonging to the genus Fusarium in various foods and feeds. They occurred worldwide and were found predominantly in corn and in corn-based animal feeds and also can be found in other crops. Contamination of food and feed with fumonisins has been implicated in and associated with a number of diseases … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 9,030 accessesView PDFCite