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294 results for “Immune”
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Research ArticleOpen accessIn the abstractInduction of the Chemokines CCL3α, CCL3α and CCL5 in Atherosclerotic PatientsAlyaa Mousa, Amani Al-Zaki, Safa Taha, Moiz BakhietChemokines recruit immune cells to inflammatory sites and promote the process of inflammation. The role of these mediators in the disease process in atherosclerosis is not fully studied. The spontaneous mRNA expression and intracellular protein production of the potential inflammatory chemokines CCL3α and CCL3β (macrophage- inflammatory protein-1α and β; CCR3α/β ligand) and CCL5 (regulated upon activation, normal T cell expressed … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 6,952 accessesView PDFCite
Research ArticleOpen accessIn the abstractSuppression of Basal and Cytokine Induced Expression of MHC, ICAM 1 and B7 Markers on Mouse Lung Epithelial Cells Exposed to Diesel Exhaust ParticlesRajiv K. Saxena, Wanda Williams, M. Ian GilmourDiesel exhaust particles (DEP) constitute a significant component of airborne particulates in urban environment. Exposure to DEP is known to enhance susceptibility to viral and bacterial infections. We hypothesized that DEP could partially exert its effect on disease susceptibility by interfering with antigen presentation required for the generation of protective adaptive immune responses. MHC class I and class II molecules, … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,607 accessesView PDFCite
Research ArticleOpen accessIn the abstractPharmacophore Pattern Identification of Tachykinin Receptor Selective Peptide Agonists: Implications in Receptor SelectivityAnjali Dike, Indu R. Chandrashekaran, Anil K. Mantha et al.The mammalian tachykinin (TK) peptides and their three Neurokinin (NK1, NK2 and NK3) receptors represent an effector system with wide-ranging actions on neuronal, airway smooth muscle, mucosal, endothelial, immune, inflammatory and remodeling cell function. Recent clinical and preclinical data suggests the pathophysiological role of TKs in various diseases including asthma, emesis and depression. The TK-NK receptor interactions and overlapping functions … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,691 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Pathology of Alzheimer Disease Elicits an In Vivo Immunological ResponseDavid J. Bonda, Kate M. Webber, Sandra L. Siedlak et al.The mechanism(s) responsible for the loss of neurons that characterizes Alzheimer disease is incompletely understood. Nonetheless, there is considerable evidence suggestive of immune abnormalities coupled to alterations in blood-brain barrier permeability that likely play a key role in both the etiology and progression of the disease. To examine these issues further, this study was designed to examine the presence of … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,115 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Acute-phase Reactants, Immunologic Markers and other Clinical and Laboratory Parameters in Patients with Pneumonia and Non-pneumonic Lower Respiratory Tract InfectionsJulio Collazos, María del Mar Martínez, Fernando IzquierdoMore efficacious tools to distinguish pneumonia from other acute lower respiratory tract infections (OALRTI) in facilities where radiologic studies are not easily or rapidly available are desirable to select the patients who should undergo chest radiographs, to avoid unnecessary visits to the emergency wards of hospitals and to optimize health resources. To this end we analyzed the relevance of many … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 7,083 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Salmonella typhimurium Challenge on Swine Growth, Nitrogen Balance, Insulin-like Growth Factor-I, and Acute Phase ProteinsJ.A. Loughmiller, S.S. Dritz, J.L. Nelssen et al.Growing barrows were used to determine the effects of an en teric disease challenge on nutrient balance, growth, acute phase proteins, and IGF-I. Pigs were challenged on d 0 with Salmonella typhimurium (S; N=21), or unchallenged and fed ad libitum (A; n=6), or unchallenged and pair-fed the same amount of feed as a challenged pig (P; n=8). Blood was collected … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 1 · 31 Mar 2007 · 7,552 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunological Evidence for Peptide-Carbohydrate Mimicry with a Group A Streptococcus Polysaccharide-Mimetic PeptideSilvia Borrelli, Rehana B. Hossany, Susan Findlay, B. Mario PintoThe immunogenicity of a peptide-protein conjugate developed by linking a peptide mimic DRPVPY of the Group A Streptococcus cell-wall polysaccharide (GAS-CWPS), to tetanus toxoid (TT) was examined. BALB/c mice were immunized three times subcutaneously following homologous or heterologous prime/boost strategies at 4- or 6- week intervals in two different experiments. DRPVPY-TT, CWPS-TT, heat-killed, pepsin-treated GAS bacteria (with exposed polysaccharide) and … …American Journal of Immunology, Vol. 2, Issue 4 · 31 Dec 2006 · 6,956 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of Virus AlgorithmsJyoti Kalyani, Karanjit S. Kahlon, Harpal Singh, Anu KalyaniSecurity of wired and wireless networks is the most challengeable in today's computer world. The aim of this study was to give brief introduction about viruses and worms, their creators and characteristics of algorithms used by viruses. Here wired and wireless network viruses are elaborated. Also viruses are compared with human immune system. On the basis of this comparison four … …Journal of Computer Science, Vol. 2, Issue 10 · 31 Oct 2006 · 6,583 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntroduction of Three Complementary Technologies into Clinical Medicine: Development of New Diagnostic and Prognostic ParametersGernot P. Tilz, Marco Wiltgen, Ulrike Demel et al.Molecular medicine leads us to understand some diseases at the molecular level. Examples are the analysis of immune complexes and receptor - anti receptor compounds used in clinical medicine. Structural changes of some serum proteins occur in inflammation, neoplasie and autoimmunity. The detection and analysis of such structural modifications may offer a new field for the diagnosis, prognosis and therapy … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 6,956 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Activation of Human and Rat Lymphocyte and Macrophage Functions by NorepinephrineRicardo Gomez-Flores, Diana Caballero-Hernandez, Richard J. Weber et al.Norepinephrine (NE) has been associated not only with increasing blood pressure, atherosclerosis, heart disease, and other life threatening conditions, but also with altering immune responses by influencing leukocyte functions. In the present study, we evaluated the in vitro effects of NE on rat thymic lymphocyte and human peripheral blood mononuclear cells (HPBMC) functions. We observed that NE marginally, but significantly … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,075 accessesView PDFCite