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281 articles for “Inhibitor”
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Research ArticleOpen accessIn the abstractA Morphological, Biochemical and Biological Studies of Halophilic Streptomyces sp. Isolated from Saltpan EnvironmentDeepika T. Lakshmipathy, Krishnan KannabiranProblem statement: Dermatophytes have developed resistance to the existing antifungal antibiotics. As a part of our continuous search we had isolated, identified and characterized actinomycetes from the halophilic environment having antagonistic activity against the dermatophytes namely Trichophyton, Microsporum and Epidermophyton. Approach: Actinomycetes were isolated from the soil sample collected from the Ennore saltpan region, Chennai, India and screened for antidermatophytic … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,743 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro and In vivo Anti-Microbial Effects of Nigella sativa Linn. Seed Extracts Against Clinical Isolates from Skin Wound InfectionsMariam A. Abu-Al-BasalcProblem statement: The developing microbial resistance to the existing anti-microbial agents has become a real challenge and a serious problem facing patients suffering from skin infections. Seeds of Nigella sativa have been used for a long time in folk medicine for the treatment of such infections. Production of new potent agents is urgently needed, especially for hospitals and health centers. … …American Journal of Applied Sciences, Vol. 6, Issue 8 · 31 Aug 2009 · 8,931 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Aqueous Extract of Aegle marmelos Fruit on Adherence and β-Lactam Resistance of Enteropathogenic Escherichia coli by Down Regulating Outer Membrane Protein CSubramaniya Bharathi Raja, Malliga Raman Murali, G. K. Malathi et al.Problem statement: Enteropathogenic Escherichia Coli (EPEC) continue to be a major health problem, leading to death due to diarrhea, predominantly in children below the age of five. Due to evolution of multi drug resistance in EPEC and side effects caused to host by antibiotics necessitated a search for alternative medicines from medicinal plants. One such medicinal plant used since ancient … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,619 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntrinsically Unstructured Proteins: Potential Targets for Drug DiscoveryPathan Salma, Chintan Chhatbar, Sriram SeshadriProblem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by their unstructured nature in the unbound state, provides a level … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,579 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Inflammatory Activity of Vitex leucoxylon L. Bark Extracts Against Freund's Complete Adjuvant Induced Arthritis in Sprague Dawley RatAlluri V. Krishnaraju, Chundi B.M. Rao, Dodda Sundararaju et al.Problem statement: Anti-inflammatory agents, particularly steroids and cyclooxygenase inhibitors are often associated with adverse side effects including, GI irritation, ulcers, hypertension and cardiac abnormalities. A safe and effective intervention is essential for the treatment of inflammatory disorders. Approach: Abstract Vitex leucoxylon L., a medicinal plant of the verbenaceae family, used in traditional medicine for relieving headache and catarrh. VL-89/185A, was … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,047 accessesView PDFCite
Research ArticleOpen accessIn the abstractDegradative Plasmid and Heavy Metal Resistance Plasmid Naturally Coexist in Phenol and Cyanide Assimilating BacteriaBahig El. Deeb, Abdullah D. AltalhiProblem statement: Heavy metals are known to be powerful inhibitors of xenobiotics biodegradation activities. Alleviation the inhibitory effect of these metals on the phenol biodegradation activities in presence of heavy metals resistant plasmid was investigated. Approach: Combination of genetic systems of degradation of xenobiotic compound and heavy metal resistance was one of the approaches to the creation of polyfunctional strains … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 2 · 30 Jun 2009 · 11,989 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effects of Air Pollution and Smoking on Cadmium Concentration in Human Blood and Correlation with Biochemical ParametersL. Zeneli, H. Paçarizi, N. M. Daci et al.Problem statement: The study described the research of the effects that the environment pollution and smoking have in cadmium concentration in human blood, as well as in the correlation between cadmium and the biochemical parameters. Approach: In a comparative study of cadmium concentration in blood of human population of two different environments in Kosovo, one nearby Kosovo Thermo Power Plants … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 2 · 30 Jun 2009 · 28,204 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of the Antibacterial Efficacy of Common Chemical Agents in Cleaning and Disinfection in Hospitals of North JordanHani A. Masaadeh, Adnan S. JaranProblem statement: Hospital cleanleness and hygene are consederd among the most important aspects of clinical success and in preventing nosocomial infections. In this study we will address the problem of effectiveness of commonly used chemical agents in cleaning and disinfection in hospitals of north Jordan. For evaluating the effectiveness of chemical agents. Approach: The minimum inhibitory concentration (MIC) was determined … …American Journal of Applied Sciences, Vol. 6, Issue 5 · 31 May 2009 · 7,793 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Higher Sludge Recycling Rate on Anaerobic Treatment of Palm Oil Mill Effluent in a Semi-Commercial Closed Digester for Renewable EnergyAlawi Sulaiman, Zainuri Busu, Meisam Tabatabaei et al.Problem statement: A 500 m3 semi-commercial closed anaerobic digester was constructed for Palm Oil Mill Effluent (POME) treatment and methane gas capture for renewable energy. During the start-up operation period, the Volatile Fatty Acids (VFA) accumulation could not be controlled and caused instability on the system. Approach: A settling tank was installed and sludge was recycled as to provide a … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Mar 2009 · 9,215 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiocontrol of Botrytis allii Munn the Causal Agent of Neck Rot, the Post Harvest Disease in Onion, by use of a New Iranian Isolate of StreptomycesM. Jorjandi, G.H. Shahidi Bonjar, A. Baghizadeh et al.Problem statement: Soil actinomycetes particularly Streptomyces spp. have showed antagonistic activity against wide range of plant pathogens. In the recent decades they have attracted high interests as biocontrol agents. Onion neck rot or gray mold caused by Botrytis allii have imposed economic post harvest damages to onion bulbs and decreased its storage durability and market value. Approach: To investigate for … …American Journal of Agricultural and Biological Sciences, Vol. 4, Issue 1 · 31 Mar 2009 · 9,942 accessesView PDFCite