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2,585 articles for “design”
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Research ArticleOpen accessIn the abstractInternalizing Versus Non-internalizing Receptors for Targeting L-Methioninase to Cancer CellsXiao-Ping Zang, Naveen R. Palwai, J. T. Pento, Roger G. HarrisonWe reported previously that L-methioninase targeted to the urokinase receptor of MCF-7 breast cancer cells is significantly more effective in inhibiting cell proliferation and migration than free L-methioninase both in vitro and in vivo. L-methioninase was targeted by linking at its amino terminus to an amino-terminal fragment (ATF) of urokinase. The ATF was selected for targeting because is has previously … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,818 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacteristics of Effective Dynamics and its Use in Developing the Product Quality and Proceeds in Inclusively FirmNasir Al KloubControlling product size type and quality is a set of technical, technological, organizational and preparatory procedures correlated in one process. Indexes for the demand for product in foreign and local markets vary according to its quality, and consequently technological processes should guarantee and warrant protects of subtle qualities and quality indexes. Securing quality of the product in all industrial sectors … …American Journal of Applied Sciences, Vol. 3, Issue 8 · 31 Aug 2006 · 6,248 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Enhanced Secure and Scalable Model for Enterprise Applications using Automated MonitoringA. Kannammal, V. Ramachandran, N. Ch.S.N. IyengarE-Business must be highly secured and scalable to provide efficient services to millions of clients on the web. This paper proposes a new approach based on shared objects to improve security and mobile agents to improve scalability. The e-business uses shared objects and mobile agents to update the clients automatically with new information. The agent that resides in the database … …Journal of Computer Science, Vol. 2, Issue 7 · 31 Jul 2006 · 6,579 accessesView PDFCite
Research ArticleOpen accessIn the abstractAutonomic Middleware Services for Just-In-Time Grid Services ProvisioningWail M. Omar, A. Taleb-Bendiab, Yasir KaramThe advent of widespread distributed computing environment, such as information systems and computational grids computing has enabled a new generation of applications that are based on seamless access, aggregation and interaction. The dramatic side of the story is a strong presence of the plea that those decentralized Grids are potentially affected by a number of primitives derived from their anatomy, … …Journal of Computer Science, Vol. 2, Issue 6 · 30 Jun 2006 · 6,584 accessesView PDFCite
Research ArticleOpen accessIn the abstractPredictive Autonomicity of Web Services in the MAWeS FrameworkEmilio P. Mancini, Massimiliano Rak, Roberto Torella, Umberto VillanoIn Web Services designs classical optimization techniques are not applicable. A possible solution to guarantee critical requirements is the use of an autonomic architecture, able to auto-configure and to auto-tune. This study presents MAWeS (MetaPL/HeSSE Autonomic Web Services), a framework whose aim is to support the development of self-optimizing predictive autonomic systems for Web service architectures. It adopts a simulation-based … …Journal of Computer Science, Vol. 2, Issue 6 · 30 Jun 2006 · 7,073 accessesView PDFCite
Research ArticleOpen accessIn the abstractRecreational Viagra Use and Sexual Risk among Drug Abusing MenDennis G. Fisher, Robert Malow, Rhonda Rosenberg et al.Until recently, the Viagra connection to HIV was anchored in older adults. However, CDC investigation showed stability in 50+ HIV diagnoses on the heels of upward trends in risk indicators among men who have sex with men (MSM) and substance abusing populations. Signs have increasingly pointed to recreational drug use among younger populations, to which Viagra is being added to … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 10,610 accessesView PDFCite
Research ArticleOpen accessIn the abstractTopical Cyclosporine A in Corneal Graft RejectionMahmood Nejabat, Jafar Khoshghadam, Masoomeh Eghtedari, Hamid HosseiniCorneal graft rejection is now the most common cause of graft failure after penetrating keratoplasty. This study was designed to determine whether, addition of 2% topical cyclosporine (CSA) to local and systemic steroids in treatment of endothelial corneal allograft rejection, would improve the outcome. A prospective randomized treatment trial was carried out on 40 consecutive corneal graft recipients, presenting with … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 7,320 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Information Management System Model for the Industrial Incidents in Saudi Arabia: A Conceptual Framework Based on SDLC MethodologySaleh Al-ZahraniThe main focus of this study has been on the development of a conceptual framework for improving the current status of industrial accidents' control. The framework is aimed to use of ICT to improve the information exchange between the Civil Defence and Industrial Sector and to provide an information management system model for the Industrial Incidents Administration System (IIAS). The … …Journal of Computer Science, Vol. 2, Issue 5 · 31 May 2006 · 6,924 accessesView PDFCite
Research ArticleOpen accessIn the abstractDigital Hardware Implementation of a Neural System Used for Nonlinear Adaptive PredictionHassène Faiedh, Chokri Souani, Kholdoun Torki, Kamel BesbesNeural networks have been widely used for many applications in digital communications. They are able to give solutions to complex problems due to their nonlinear processing and their learning and generalization. Neural networks are one of the key technologies for the communication domain and accordingly a special effort may be expected to be paid to real time hardware implementation issues. … …Journal of Computer Science, Vol. 2, Issue 4 · 30 Apr 2006 · 6,767 accessesView PDFCite
Research ArticleOpen accessIn the abstractSoftware Process Modeling Using Role and CoordinationAtil Fadila, Ghoul Said, Bounour NoraThe term software process joins all activities that have to be achieved in order to develop software. It has been shown that modeling such processes is difficult and expensive task. It's confirmed by diversity of software processes modeling approaches which are however, not satisfactory. This study deals with an area of growing importance and presents a role- and coordination- based … …Journal of Computer Science, Vol. 2, Issue 4 · 30 Apr 2006 · 6,575 accessesView PDFCite