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Research ArticleOpen accessIn the abstractEfficacy of Pravastatin in Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) and Protease Inhibitor (PI)-based HAART in HIV-Infected PatientsSusan A. Eaton, Anita P. Rahman, Sean T. Nguyen et al.Pravastatin has generally been considered a safe and effective option for HIV-infected patients on highly active antiretroviral therapy (HAART). However, pravastatin concentrations are known to significantly decrease with concomitant efavirenz (EFV) use. Currently there are no studies determining if these reductions in pravastatin possibly translate into an attenuation of its lipid lowering efficacy when used in HIV-infected patients on non-nucleoside … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 6,959 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhysical Characterizations of Sands and Their Influence in Fall VelocityRuiz-Martinez Gabriel, Mendoza-Baldwin Edgar, Silva-Casarín RodolfoCancun beach is one of the most important tourist resorts on the Mexican coast, and is of prime importance to the local and national economies. As a result of the intense use of the beach and the unavailability of sand reserves, the extreme weather events that occur in the region (hurricanes) have permanently damaged the beach. Over the last two … …American Journal of Environmental Sciences, Vol. 4, Issue 3 · 30 Jun 2008 · 6,460 accessesView PDFCite
Research ArticleOpen accessIn the abstractVulnerability Assessment of Power System Using Radial Basis Function Neural Network and a New Feature Extraction MethodAhmed M.A. Haidar, Azah Mohamed, Aini HussainVulnerability assessment in power systems is important so as to determine how vulnerable a power system in case of any unforeseen catastrophic events. This paper presents the application of Radial Basis Function Neural Network (RBFNN) for vulnerability assessment of power system incorporating a new proposed feature extraction method named as the Neural Network Weight Extraction (NNWE) for dimensionality reduction of … …American Journal of Applied Sciences, Vol. 5, Issue 6 · 30 Jun 2008 · 7,153 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarthquake Risk Management Strategy Plan Using Nonparametric Estimation of Hazard RateAflaton Amiri, Ramin TabatabaeiEarthquake risk is defined as the product of hazard and vulnerability studies. The main aims of earthquake risk management are to make plans and apply those for reducing human losses and protect properties from earthquake hazards. Natural risk managers are studying to identify and manage the risk from an earthquake for highly populated urban areas. They want to put some … …American Journal of Applied Sciences, Vol. 5, Issue 5 · 31 May 2008 · 6,744 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic Interventions in AgingSuresh I.S. RattanSingle or multiple exposure to low doses of potentially harmful agents can have a variety of anti-aging and longevity-extending hormetic effects. These hormetic stressors include irradiation, physical activity, food limitation, heat, hypergravity, dietary components and reactive oxygen species. Molecular mechanisms facilitating the hormetic effects are being elucidated and comprise a cascade of stress response and maintenance and repair pathways. Although … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,831 accessesView PDFCite
Research ArticleOpen accessIn the abstractCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,009 accessesView PDFCite
Research ArticleOpen accessIn the abstractInduction of the Chemokines CCL3α, CCL3α and CCL5 in Atherosclerotic PatientsAlyaa Mousa, Amani Al-Zaki, Safa Taha, Moiz BakhietChemokines recruit immune cells to inflammatory sites and promote the process of inflammation. The role of these mediators in the disease process in atherosclerosis is not fully studied. The spontaneous mRNA expression and intracellular protein production of the potential inflammatory chemokines CCL3α and CCL3β (macrophage- inflammatory protein-1α and β; CCR3α/β ligand) and CCL5 (regulated upon activation, normal T cell expressed … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 6,952 accessesView PDFCite
Research ArticleOpen accessIn the abstractRedox Sensing and Cardiac Myocyte Loss: Some Recent InsightsShyamal K. GoswamiGeneration of reactive oxygen-nitrogen species (ROS/RNS) has long been ascribed to pathophysiological conditions like ageing, neurodegenerative and cardiovascular disorders. However, more recent evidences suggest that while generation of ROS/RNS at a higher threshold is deleterious, at a lower dose these can act as second messengers, influencing specific cellular events like cell growth and differentiation, embryonic development, protection against ischemic injuries … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,349 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeterministic Timed AFA: A New Class of Timed Alternating Finite AutomataAbdelaziz Fellah, Zachary Friggstad, Soufiane NoureddineTimed Alternating Finite Automata (TAFA), a natural generalization of Timed Finite Automata (TFA), are synchronous and powerful models for real-time computations. They become an effective and expressive model for developing embedded systems with real-time constraint computations which are required in many applications. We introduce Deterministic Timed Alternating Finite Automata (DTAFA), a new class of timed alternating finite automata, extended with … …Journal of Computer Science, Vol. 3, Issue 1 · 31 Jan 2007 · 7,499 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical Effects of Recombinant Porcine Somatotropin on Pig Fetal Growth and Metabolism: A ReviewD. Villanueva-García, S. A. Olmos-Hernández, D. Mota-Rojas et al.Prenatal development is mainly dependent on a close interrelation between nutritional supply use and regulation by hormones and growth factors. Mechanisms during early embryonic development are sensitive to manipulation through selected management strategies of the sow and modifications of this strategy may serve as a model for the examination of molecular and cellular events controlling early embryonic growth. The administration … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 6,620 accessesView PDFCite