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256 articles for “marker”
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Research ArticleOpen accessIn the abstractThe Functional Effect of Kaempferia Parviflora on Ischemic Stroke in RatsWathita Phachonpai, Sinthuporn Maharun, Terdthai Tong-Un et al.Problem statement: Oxidative stress has been implicated as important factors in the pathogenesis of cerebral ischemia-induced behavioral deficits particularly memory. Growing attention is being paid to traditional medicinal plants possessing antioxidant activity, as they have been proved therapeutically/prophylactically fruitful against stroke condition. Present study provides evidence of the neroprotective effects of a Thai traditional herb, Kaempferia Parviflora (KP) extract, against … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 2 · 16 Mar 2012 · 8,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiomarkers of Oxidative DNA Damage and Soluble Fas/Fas Ligand in Type 2 Diabetic PatientsMohamed H. Mahfouz, Ibrahim A. Emara, Ghada A. OmarProblem statement: Involvement of oxidative stress in the pathogenesis of diabetic complications has been proposed. 8-hydroxy-2'-deoxyguanosine (8-OHdG) has been reported to serve as a new sensitive biomarker of the oxidative DNA damage in vivo. Apoptosis via Fas/Fas Ligand (FasL) interactions has been proposed to be a major T-cell-mediated effector mechanism in autoimmune diabetes. This study was undertaken to investigate whether … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 3 Feb 2012 · 7,106 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Diversity in Cichla monoculus (Spix and Agassiz, 1931) Populations: Implications for Management and ConservationCarlos Henrique Dos Anjos Dos Santos, Carolina Fernandes Silva De Sousa, Maria de Nazare Paula-Silva et al.Problem statement: The object of this study was to examine the genetic structure and gene flow in Cichla monoculus populations in seven varzea lakes of the Solimoes River using Randomly Amplified Polymorphic DNA (RAPD) markers, to monitor the region where petroleum is transported in the Amazon basin. Approach: The loss of genetic diversity is one of the main factors leading … …American Journal of Environmental Sciences, Vol. 8, Issue 1 · 30 Jan 2012 · 8,517 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy and Identification of Insulin-Like Growth Factor-I Gene Polymorphisms in Zel Sheep PopulationSeyed Mohsen Kazemi, Cyrus Amirinia, Hossein Emrani, Shahaboddin GharahveysiProblem statement: The IGFs play an important role in regulating somatic growth according to nutritional conditions. Polymorphisms of IGF gene are reported to be significantly associated with many traits. Approach: In these study 142 samples of DNA from Zel sheep were used for detecting the polymorphisms of promoter region of the Insulin-like Growth Factor-1 (IGF-1) gene. Therefore DNA extracted from … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 13 Jan 2012 · 7,739 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of L-Carnitine and Cinnamon Extract Treatment on Lens Crystallins of Rats Fed High Fructose DietMohamed H. Mahfouz, Amany Abd El-Ghaffar, Mona A. Mohamed, Hala M. GhanemProblem statement: Rats fed high dietary fructose are documented to form an acquired model of insulin resistance; the present study aims to investigate possible changes in lens crystallins of rats fed high fructose diet and the effects of administration of each exogenous L-Carnitine (CA) and Cinnamon Extract (CE) on protein glycation, oxidative stress and redox homeostasis in this rat model. … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 3 Aug 2011 · 8,711 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Arthritic Activity of the Methanolic Leaf Extract of Urtica pilulifera L. on Albino RatsSuha Abudoleh, Ahmad Disi, Eyad Qunaibi, Talal AburjaiProblem statement: Urtica pilulifera (Urticeacae) has been used in folk medicine to alleviate inflammation and arthritis. In this study the anti-arthritic effect of methanolic leaf extract of the plant was evaluated and compared to untreated control as well as ibuprofen-treated groups in a rat model of Complete Freund's Adjuvant (CFA)-induced arthritis. Approach: Arthritis was induced by injecting CFA subcutaneously into … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 14 Jun 2011 · 10,431 accessesView PDFCite
Research ArticleOpen accessIn the abstractToxicity evaluation of yoyo 'cleanser' bitters and fields Swedish bitters herbal preparations following sub-chronic administration in ratsMartins Ekor, Odusoga Adewale Osonuga, Adesina Olalekan Odewabi et al.Problem statement: Owing to numerous adverse effects of most orthodox pharmaceuticals, the use of herbal remedies in treatment and prevention of diseases is gaining much attention, especially in developing countries. The increase patronage of these remedies is often predicated on the assumption that they are harmless since they are prepared from natural sources. However, toxicity related to herbal medicines is … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 10,198 accessesView PDFCite
Research ArticleOpen accessIn the abstractCognitive-Enhancing and Antioxidant Activities of Quercetin Liposomes in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of Alzheimer’s Disease (AD). Antioxidant intake is beneficial to delay or inhibit the progression of this disease. Quercetin, a bioflavonoid in fruits and vegetables, has a powerful antioxidant activity both in vitro and in vivo. Claims that quercetin has many biological activities. However, quercetin is rapidly … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 31 Oct 2010 · 7,880 accessesView PDFCite
Research ArticleOpen accessIn the abstractTo Seek the Hidden MonsterK. K. Rahul, S. AmbujamProblem statement: The asymptomatic stage of HIV infection is dealt with in detail in all Dermatology books. Patients in this stage present with skin lesions that occur even in the immunocompetent. However when these lesions recur, are atypical, aggressive or unresponsive to treatment, it is worthwhile to go back into the history to ascertain if there is a history of … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 6,927 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatitis B and C Positivity in Various Categories of Human Immunodeficiency Virus Seropositive Individuals in a Regional STD Centre-an Eight-Year Evaluation of Trends and Risk FactorsSumathi Muralidhar, Manju Bala, Rakesh Kumar Jain et al.Problem statement: Among the various infections whose incidence has increased since the advent of HIV/AIDS, Hepatitis B and C stand out clearly. This is so because the routes of transmission of these infections are essentially the same as those of HIV/AIDS, making co-infections a common occurrence. The risk of infection for Hepatitis B and C is several times more than … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 6,925 accessesView PDFCite