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2,311 articles for “Yi Lin”
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Research ArticleOpen accessIn the abstractImatinib Mesylate Inhibits Glucose Uptake in Gastrointestinal Stromal Tumor Cells by Downregulation of the Glucose Transporters Recruitment to the Plasma MembraneHans Prenen, Cristiana Stefan, Bart Landuyt et al.Imatinib mesylate, the inhibitor of the KIT protein tyrosine kinase that is constitutively activated in Gastrointestinal Stromal Tumors (GISTs), has been established as the first highly effective drug in the treatment of patients with advanced GISTs. Recent studies suggest that changes in the glucose metabolism could be an additional mechanism of the anti-proliferative action of imatinib. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,248 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiosensor Based on Xanthine Oxidase for Monitoring Hypoxanthine in Fish MeatHelena S. Nakatani, Luciane V. dos Santos, Cristiano P. Pelegrine et al.An amperometric enzyme electrode for the detection of hypoxanthine in fish meat is described. The hypoxanthine sensor was prepared from xanthine oxidase immobilized by covalent binding with glutaraldehyde and bovine serum albumin on a nafion-coated platinum disc electrode. The responses for hypoxanthine were obtained in 0.1 mol L-1 phosphate buffer (pH 7.0), at potential of 600mV vs Ag/AgCl. This biosensor … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 8,602 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression, Purification and Activity Assay of Two New Recombinant Antagonists of Fibrinogen ReceptorJianbo Yang, Jia Yao, Kun Yang et al.The gene sequence of Decorsin which is extracted from a kind of North American leeches was synthesized. Two recombinant proteins, Annexin V plus Decorsin (AnnV-D39) and Annexin V plus the carboxyl terminal 27 amino acid residues of Decorsin(AnnV-D27), were constructed. And a 10 amino acids linker peptide of GGGGSGGGGS was inserted between Annexin V and Decorsin in AnnV-D39. Using pET-28(a+) … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,918 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Note on “Surface Roughness Prediction Model in Machining of Carbon Steel by PVD Coated Cutting Tools”Godfrey C. OnwuboluAn article published in this journal by Sahin and Motorcu[1] developed a surface roughness model based on the response surface method, multiplicative-logarithmically linearized approach for determination of the cutting parameters in turning of AISI 1040 carbon steel. Their published results for the surface roughness show that it appears Sahin and Motorcu[1] have obtained wrong constants (C, m, n, p), thereby … …American Journal of Applied Sciences, Vol. 2, Issue 6 · 30 Jun 2005 · 7,250 accessesView PDFCite
Research ArticleOpen accessIn the abstractA New Spectrophotometric Method for Determination of Iron in Herbs, Spices and Beans with 2,6-Diacetylprydine Dioxime and 2-Acetylpyridine MonoximeZ. R. Komy, E. A. Abu-Gharib, A. DesokyThe reaction of iron (II) with 2, 6-diacetylprydine dioxime (H2dapd) and 2-acetylprydine monoxime (Hapm) in 10% and 60% v/v ethanol-water solution at pH 2.5 and 7.5, respectively, were studied using direct and first derivative spectrophotometry. Fe (III) is reduced by H2dapd and gives iron (II) complex. A simple, rapid, selective and sensitive method for the determination of Fe (II), Fe … …American Journal of Applied Sciences, Vol. 2, Issue 4 · 30 Apr 2005 · 6,966 accessesView PDFCite
Research ArticleOpen accessIn the abstractOOST: An Object Oriented Tool for Satellite Orbit DesignA. A. Salem, M. Zaki, A. A. WahdanIn this study the problems of satellite orbit design and simulation are tackled and an object oriented satellite tool OOST is developed. The tool with its three main modules enables the user to plan and design different satellite missions. It performs all orbital calculations needed, simulates the target orbit and performs analysis on the current active satellite(s). The simulation module … …American Journal of Applied Sciences, Vol. 2, Issue 4 · 30 Apr 2005 · 7,213 accessesView PDFCite
Research ArticleOpen accessIn the abstractEstimation of Vibrations in Switched Reluctance Motor DrivesS. Balamurugan, R. ArumugamThis study discusses a simple algorithm for estimation and reduction of Vibrations in a Switched Reluctance Motor (SRM) using magnetic circuit simulation in MATLAB/SIMULINK Environment. A Non-linear model is developed using magnetic circuit equations, wherein non-linearity is added using a inductance profile with back EMF. Dynamic characteristic of the SRM is simulated and the same is being verified experimentally. In … …American Journal of Applied Sciences, Vol. 2, Issue 4 · 30 Apr 2005 · 6,832 accessesView PDFCite
Research ArticleOpen accessIn the abstractScheme for ISDN/DECT Wireless Internetworking and VerificationMaher Dababneh, Ibrahim QatawnehA novel scheme to access the basic rate service of the Integrated Service Digital Network (ISDN) using the Digital Enhanced Cordless Telephone (DECT) radio interface standard is presented. The S-interface in the ISDN reference configuration has been used for the ISDN interface and the unprotected class 0 transmissions are used for the DECT interface. The design of a state of … …American Journal of Applied Sciences, Vol. 2, Issue 4 · 30 Apr 2005 · 7,208 accessesView PDFCite
Research ArticleOpen accessIn the abstractE-DemocracyKevin Curran, Eric NicholsDemocracy means majority rule. This raises some interesting questions. In a truly democratic society, when a majority of citizens vote for one candidate to govern them, then that person would be the elected governor of those people. Following this line of reasoning, if the majority of people do not vote for a leader, does democracy mean not having a leader? … …Journal of Social Sciences, Vol. 1, Issue 1 · 31 Mar 2005 · 7,068 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Investigation of the Relationship among Analyst Following, Managerial Ownership and Firm Valuation: From the Perspective of Agency TheoryI. J. ChenIn this study, the relationship among analyst following, managerial ownership and firm valuation is investigated from the perspective of agency theory by using a nonlinear simultaneous equation model. The data from the Taiwan stock market verify the proposed hypotheses with a nonlinear three-stage least-square procedure. The empirical results show that managerial ownership (serving an internal monitoring function) and number of … …Journal of Social Sciences, Vol. 1, Issue 1 · 31 Mar 2005 · 7,039 accessesView PDFCite