Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

227 articles for “cell approach”
Set a search alert
Also matching:2 special issues
Research ArticleOpen accessIn the abstractThe Effects of Recombinant Human Erythropoietin and Tamoxifen on Growth and Angiogenesis of Mammary Tumor in Sprague-Dawley RatA. K. Sairah, A. Rasedee, O. Sheikh et al.Problem statement: Erythropoietin receptor (EPOR) has been detected in breast cancer cells and speculated to be involved in cancer growth, viability and angiogenesis. This has risen suspicious that EPO administration may enhance the severity of cancer. Approach: This study was undertaken to determine the effects of rHuEPO, Tamoxifen and their combination on the growth and angiogenesis of mammary tumor. Female … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 1 · 31 Mar 2009 · 7,807 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,100 accessesView PDFCite
Research ArticleOpen accessIn the abstractExperimental Investigation on Geomechanical Properties of Tropical Organic Soils and PeatBujang B.K. Huat, Afshin Asadi, Sina KazemianProblem statement: Organic soils and peat were believed to be geotechnically problematic due to their very high compressibility, very low shear strength and difficult accessibility. Although conventional soil mechanics theory could be applied to the soils, it was found that important anomalies existed which required special considerations. Correlations between geomechanical parameters for the soils were known to be important for … …American Journal of Engineering and Applied Sciences, Vol. 2, Issue 1 · 31 Mar 2009 · 10,177 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlasmid Mediated Tolerance and Removal of Heavy Metals by Enterobacter spBahig El-DeebProblem statement: The role of plasmid in the heavy metal resistance and accumulation by endophytic bacteria was investigated. Approach: The experimental results showed that high level plasmid mediated Cd2+ and Zn2+ resistance in this strain is due to decreased Cd2+ and/or Zn2+ uptake/accumulation by resistance strain. Results: Based on the fact that subsequent plasmid curing experiments demonstrated that the ability … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,006 accessesView PDFCite
Research ArticleOpen accessIn the abstractLack of Association of Glutathione S-transferase Gene Polymorphisms in Iranian Prostate Cancer SubjectsB. Sahar Ansari, R. Vasudevan, M. Mirinargesi et al.Problem statement: Glutathione S-transferase is super family genes that encode enzymes which involve in the detoxification of the cell and protects DNA from damage. Conflicting results was found in several studies in association with GSTT1 and GSTM1 gene polymorphisms and prostate cancer. In this study, we determined the association between the GSTT1 and GSTM1 gene polymorphism and prostate cancer in … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,279 accessesView PDFCite
Research ArticleOpen accessIn the abstractSignaling Pathways Involved In Dengue-2 Virus Infection Induced RANTES OverexpressionYing-Ray Lee, Huan-Yao Lei, Shun-Hua Chen et al.Dengue viruses participate in liver inflammation by inducting the expression of various chemokines including Regulated on Activation Normal T-cell Expressed and Secreted (RANTES). However, the underlying signaling remains unknown. Here, we reveal that Ras, Raf-1 and three mitogen-activated protein kinases (MAPKs) p38, extracellular signal-regulated kinase (Erk), and c-jun-NH2-terminal kinase (JNK) can be activated or phosphorylated in dengue-2 virus infected hepatocyte … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,176 accessesView PDFCite
Research ArticleOpen accessIn the abstractTissue Engineering of Articular Cartilage: A Mini-ReviewRadoslav Zamborsky, Jana Rusnakova, Andreas NicodemouDamage of articular cartilage due to congenital anomaly, injury or pathological process may lead in decreasing of life quality of affected patients. In many cases, conventional therapeutical approaches may not bring expected results. Tissue engineering by the combination of material technology and cell-based therapy may represent hope for these patients. The main goal of this review article is to summarize … …OnLine Journal of Biological Sciences, Vol. 14, Issue 4 · 5 Jan 2015 · 6,929 accessesView PDFCite
Research ArticleOpen accessIn the abstractRADIOSENSITIZATION OF CANCER STEM CELLS: TARGETING TGFβ, NOTCH OR TELOMERASE TO IMPROVE TUMOR RESPONSE O RADIOTHERAPYIgnacio Fernandez-GarciaRadiation resistant cancer stem cells are the main reason for treatment failure and tumor recurrence after cancer radiotherapy. Increasing biological evidences demonstrate that these cells possess the capacity to repair radiation induced DNA damage, protect themselves from radiation derived reactive oxygen species, survive and proliferate after several fractions of radiotherapy and finally, repopulate the heterogeneity of the tumor. Thus, targeting … …Current Research in Medicine, Vol. 5, Issue 2 · 16 Jul 2014 · 7,464 accessesView PDFCite
Research ArticleOpen accessIn the abstractRendezvous with Tat: Transactivator of Transcription during Human Immunodeficiency Virus PathogenesisSneham Tiwari, Madhavan P.N. Nair, Shailendra K. SaxenaAcquired immune deficiency syndrome is a deadly disease caused by HIV, declared as a global catastrophe engulfing millions of lives per year. It took ~1.8 million lives in the year 2010 alone, as per reports of UNAIDS. HIV-1 is an enveloped retrovirus, having genome composed of two copies of ssRNA. It attacks the T-lymphocytes of the hosts, causes several multifaceted … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 31 Jul 2012 · 7,627 accessesView PDFCite
Research ArticleOpen accessIn the abstractMixed Species Grazing of Cattle and Goats on Gastrointestinal Infections of Haemonchus ContortusRenita Marshall, Sebhatu Gebrelul, Lisa Gray, Yemane GhebreiyessusAt the present time, the meat of goat is the fastest growing class of livestock in the U.S.A. Due to the sub-tropical climate in the South Eastern region of the US, internal parasites pose a major constraint to the industry. The blood-feeding nematode, Haemonchus contortus results in production losses and even death in untreated animals. The control of H. contortus … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 2 · 4 Jul 2012 · 8,531 accessesView PDFCite