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235 results for “P. Michael”

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Research ArticleOpen accessIn the author namesThe Phenotypically Suppressed Cancer Cell As a Therapeutic TargetKimberly D. Kyker, Jessica E. Thorpe, Satyendra S. Shenoy et al.Bladder cancer recurs in up to 70% of patients judged to be tumor-free after treatment. Like other cancers, delayed appearance of metastases is common. These findings suggest the malignant phenotype can be suppressed, to emerge later. Following up on previous research in our laboratory showing that normal extracellular matrix can suppress the malignant phenotype of bladder cancers, we here demonstrate … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,474 accessesView PDFCite
Research ArticleOpen accessIn the author namesMapping QTLs Linked to Physio-Morphological and Plant Production Traits under Drought Stress in Rice (Oryza sativa L.) in the Target EnvironmentS. Michael Gomez, S. Satheesh Kumar, P. Jeyaprakash et al.Drought stress is a major constraint for rice (Oryza sativa L.) production and yield stability in rainfed ecosystems. Identifying genomic regions (QTLs) contributing in drought resistance will help to develop rice cultivars suitable for water-limiting environments through marker-assisted breeding. QTLs linked to physio-morphological and plant production traits under drought stress in the field were mapped by evaluating 177 F6 recombinant … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 14,482 accessesView PDFCite
Research ArticleOpen accessIn the author namesRole of HIV-1 Infection in Addictive Behavior: A Study of a HIV-1 Transgenic Rat ModelSulie L. Chang, Michael VigoritoEpidemiological research indicates that drug abuse is prevalent among individuals infected with HIV-1. Evidence from preclinical research also suggests that drugs of abuse exacerbate the progression of neuropathological changes in the HIV-1 infected brain probably through common mechanisms of neuronal injury. The effects of HIV-1 on the efficacy and abuse potential of controlled drugs such as morphine, however, has not … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,634 accessesView PDFCite
Research ArticleOpen accessIn the author namesTests of Glass Insulating Panels with Embedded Laminated Point ConnectionsMichaela Zdražilová, Zdeněk Sokol, Martina EliášováEmbedded laminated point connections represent a progressive way of glass structures connecting. However, detail information about their performance is not available yet and the design procedure is mostly based on experimental work and previous experience of designers. Within an ongoing research at the Faculty of Civil Engineering of the Czech Technical University in Prague, a set of real-scale insulating glass … …International Journal of Structural Glass and Advanced Materials Research, Vol. 6, Issue 1 · 9 Mar 2022 · 10,161 accessesView PDFCite
Research ArticleOpen accessIn the author namesFrequency of Single Nucleotide Polymorphisms of the SLCO1B1 Gene in Slavic Population of Central EuropeMichaela Mikulová, Veronika Kramarova, Ján ChandogaThe organic anion transporting polypeptide 1B1 (encoded by SLCO1B1 gene) is involved in the active cellular influx of diverse endogenous compounds and several drugs, such as HMG-CoA reductase inhibitors (statins). Two common polymorphisms c.388A>G and c.521T>C in SLCO1B1 alter transport activity of this transporter and play an important role in the pharmaceutical response to many drugs. The aim of our … …OnLine Journal of Biological Sciences, Vol. 16, Issue 4 · 11 Dec 2016 · 7,313 accessesView PDFCite
Research ArticleOpen accessIn the author namesCELL DETACHMENT BY PROLYL-SPECIFIC ENDOPEPTIDASE FROM WOLFIPORIA COCOSNicole Mika, Katharina Cierpka, Michaela C. Lange et al.As requirements for Advanced Therapy Medicinal Product (ATMP) production differ from other production processes (e.g., therapeutic protein production), cell detachment is often a crucial step for the process success. In most cases, cell detachment is done enzymatically. Although many peptidases are established in cell culture in R&D, e.g., Trypsin as gold standard, many of them seem to be unsuitable in … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 8 Feb 2014 · 8,159 accessesView PDFCite
Research ArticleOpen accessIn the abstractA CNN-KNN Based Recognition of Online Handwritten Symbols within Physics Expressions Using Contour-Based Bounding Box (CBBS) Segmentation TechniqueUjwala Kolte, Sachin Naik, Vidya KumbharArtieres, T., Marukatat, S., & Gallinari, P. (2007). Online Handwritten Shape Recognition Using Segmental Hidden Markov Models. IEEE Transactions on Pattern Analysis and Machine Intelligence, 29(2), 205–217. https://doi.org/10.1109/tpami.2007.38 Baró, A., Riba, P., Calvo-Zaragoza, J., & Fornés, A. (2019). From Optical Music Recognition to Handwritten Music Recognition: A baseline. Pattern Recognition Letters, 123, 1–8. https://doi.org/10.1016/j.patrec.2019.02.029 Bresler, M., Prua, D., & Hlavác, … …Journal of Computer Science, Vol. 20, Issue 7 · 7 May 2024 · 6,282 accessesView PDFCite