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207 articles for “Inflammatory”
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Research ArticleOpen accessIn the abstractProtection against Lipopolysaccharide-induced Death by An Anti-Interleukin-6 Monoclonal AntibodyBailin Liang, Debra Gardner, Don Griswold, Xiao-yu R. SongSepticemia is frequently associated with serious complications and high mortality despite recent advances in treatment with antibacterial agents. Infectious organisms or their soluble products initiate septic shock through a complex cytokine cascade. Lipopolysaccharide (LPS) induced excessive production of inflammatory cytokines is regarded as a model of septic shock. Experiments of LPS-induced excessive cytokine production were conducted in Balb/c mice for … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 6,856 accessesView PDFCite
Research ArticleOpen accessIn the abstractWound Healing Process of Uncomplicated “Rusterholz” Ulcer, Following Treatment by Wooden Block and Hoofgel® in Bovine Hoof: Histopathological AspectsH. Azarabad, I. Nowrouzian, E. Soleymani et al.A broad and very detailed histopathological knowledge on cutaneous wound healing particularly in human skin is available, but few studies have documented this event in bovine claw sole ulcers. It seems the mechanism of wound healing might be basically the same followed by second intention healing which is finished in a period of time by formation of granulation tissue in … …American Journal of Animal and Veterinary Sciences, Vol. 1, Issue 2 · 31 Dec 2006 · 7,847 accessesView PDFCite
Research ArticleOpen accessIn the abstractCPI-1189 Protects Against Dextran Sulfate Sodium-induced Colitis in MiceBeverley Greenwood-Van Meerveld, Karl R. TylerNitrone-related therapeutics (NRTs) represent a new class of small molecules potentially effective in the treatment of inflammatory bowel disease (IBD) by protecting cells from damage caused by excess inflammation and/or oxidative stress. The goal of this study was to determine the efficacy and potency of CPI-1189, a novel therapeutic agent, in dextran sulfate sodium (DSS)-induced colitis in mice. Mice received … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 6,713 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Mechanisms for Altered Glucose Homeostasis in HIV InfectionPaula W. HruzA complete understanding of the molecular mechanisms leading to HIV-associated insulin resistance remains elusive. Complex interrelationships between genetic predisposition, disease-related body changes and multidrug therapy all contribute to alterations in glucose homeostasis. These abnormalities can be differentiated between acute and reversible changes directly induced by HAART medications and more chronic and less reversible changes due to the development of lipodystrophy … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,877 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntroduction of Three Complementary Technologies into Clinical Medicine: Development of New Diagnostic and Prognostic ParametersGernot P. Tilz, Marco Wiltgen, Ulrike Demel et al.Molecular medicine leads us to understand some diseases at the molecular level. Examples are the analysis of immune complexes and receptor - anti receptor compounds used in clinical medicine. Structural changes of some serum proteins occur in inflammation, neoplasie and autoimmunity. The detection and analysis of such structural modifications may offer a new field for the diagnosis, prognosis and therapy … …American Journal of Immunology, Vol. 2, Issue 1 · 31 Mar 2006 · 6,956 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Cytokines in the Regulation of Glioma Tumour Growth and AngiogenesisChristina Piperi, Athanasios Zisakis, Robert W. Lea, Anastasios KalofoutisMalignant glioblastomas are the most common type of primary brain tumors accounting for more than 50% of all intracranial gliomas. Due to their aggressive nature, recurrent growth, and their extremely poor prognosis for survival, research approaches have made little progress in advancing treatment of these tumours which have the ability of both modulating host immune function and neutralizing immune-based therapies. … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,868 accessesView PDFCite
Research ArticleOpen accessIn the abstractExtracts of Pumpkin (Cucurbita pepo L.) Seeds Suppress Stimulated Peripheral Blood Mononuclear Cells in vitroChristiana Winkler, Barbara Wirleitner, Katharaina Schroecksnadel et al.In the traditional medicine in North America and Mexico, pumpkin seeds have been used as an anthelmintic agent and for supportive treatment in functional disorders of the bladder. Also anti-inflammatory and cardioprotective activity of pumpkin seeds is discussed. Three different extracts of pumpkin seeds were prepared and effects were investigated in unstimulated human peripheral blood mononuclear cells and in cells … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 10,711 accessesView PDFCite