Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

199 results for “acute”
Set a search alert
Research ArticleOpen accessIn the abstractCurcuma longa, Glycyrrhiza glabra and Moringa oleifera Ameliorate Diclofenac-induced Hepatoxicity in RatsAlaaeldin A. HamzaAlthough treatment with therapeutic agents may be one of the main causes of liver toxicity, there have been only limited attempts at thorough research efforts to seek solution. Diclofenac (DIC) is a widely used anti-inflammatory drug that causes liver toxicity. This DIC-induced hepatotoxicity was found to be associated with oxidative damage. In this report, extracts of herbal plants that are … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 9,614 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Mechanisms for Altered Glucose Homeostasis in HIV InfectionPaula W. HruzA complete understanding of the molecular mechanisms leading to HIV-associated insulin resistance remains elusive. Complex interrelationships between genetic predisposition, disease-related body changes and multidrug therapy all contribute to alterations in glucose homeostasis. These abnormalities can be differentiated between acute and reversible changes directly induced by HAART medications and more chronic and less reversible changes due to the development of lipodystrophy … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,877 accessesView PDFCite
Research ArticleOpen accessIn the abstractStability of Neodymium(III) Complexes of 4-Hydroxycoumarins with Anticoagulant ActivityIrena Kostova, Irina NikolovaComplexes of neodymium(III) with 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one, 4-hydroxy-3-[1-(4-chlorophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one and 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one were synthesized by mixing of water solutions of neodymium(III) nitrate and the respective ligands, in amounts equal to metal: ligand molar ratio of 1: 3. The complexes were characterized and identified by elemental analysis, conductivity, IR and 1H NMR spectral data. DTA and TGA have been applied to confirm the compositions of … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 2 · 30 Jun 2006 · 7,554 accessesView PDFCite
Research ArticleOpen accessIn the abstractSpirulina protects against cadmium-induced hepatotoxicity in ratsAmr Amin, Alaaeldin A. Hamza, Sayel Daoud, Waleed HamzaCadmium (Cd) is an environmental and industrial cumulative pollutant that most affects many organs specially the liver. The protective effect of Spirulina, filamentous blue green algae, on Cd – induced oxidative stress and hepatotoxicity was evaluated in male rats. Oral administration of water extract of Spirulina for seven days followed by an acute toxic dose of Cd (3.5 mg kg … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 2 · 30 Jun 2006 · 11,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractAction of Calciotropic Hormones on Bone Metabolism-Role of Vitamin D3 in Bone Remodeling EventsCatharine Andresen, Ellen Olson, Chudy I. Nduaka et al.Vitamin D3 is known to have immunosuppressive effects that can be beneficial for treatment of immune disorders and transplant rejection, however therapeutic application is limited due to hypercalcemia and hypercalcuria. The goal of our studies was to explore both the acute and steady state effects of vitamin D3 on bone remodeling as potential limiting factors to broader use of vitamin … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 8,816 accessesView PDFCite
Research ArticleOpen accessIn the abstractInefficacy of Topical Diclofenac in Arthritic HorsesNicolás F. Villarino, Tomas J. Vispo, Marcos et al.The objective of the present study was test the anti-inflammatory efficacy of diclofenac dietilamine, applied epicutaneously at a dose rate of 0.44 mg kg-1, in a model of acute arthritis in horses. Four clinical end-points, as well as two biochemical markers, were used as surrogate markers of the required clinical response (analgesia, anti-inflammatory). Low diclofenac concentrations were measured in blood … …American Journal of Animal and Veterinary Sciences, Vol. 1, Issue 1 · 30 Jun 2006 · 7,608 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of Beta-hemolytic Streptococcus Carrier State and its Sensitivity to Different Antibiotics among Guidance - School Children in Kerman-IranFatemeh Nabipour, Mohammadali TayarzadehGroup A β-hemolytic streptococcus is the most frequently isolated pathogen in acute pharyngitis and pharingotonsilits Cases in school - aged children. Resulting in dangerous complications such as rheumatic fever and glomerulonephritis, diagnosis and treatment of the disease would be of great importance. The aim of this study was determination of the frequency of group A β-hemolytic streptococcus carriers in middle … …American Journal of Infectious Diseases, Vol. 1, Issue 2 · 30 Jun 2005 · 6,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractInduction of Caspase-dependant Apoptosis by Enterovirus 70 in Human Lens Epithelial SRA01/04 CellsDequan Chen, Chris Duggan, Donald E. Texada et al.Enterovirus 70 (EV70), an etiological agent of acute hemorrhagic conjunctivitis (AHC), induces apoptosis in human Chang’s conjunctival (HCC) cells. EV70 is also able to infect and replicate in some other human cells such as human lens epithelial SRA01/04 cells and U937 cells. EV70 infection was found to induce apoptosis in SRA01/04 cells. During EV70-induced apoptosis of SRA01/04 cells, the expression … …American Journal of Infectious Diseases, Vol. 1, Issue 2 · 30 Jun 2005 · 6,636 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpidemiology of Intensive Care Unit Infections and Impact of Infectious Disease Consultants in Managing Resistant InfectionsK. P. Ravi, Suresh Durairajan, Sankalp Parivar et al.Choice of empiric antibiotics in India have generally been guided by western data and guidelines. However, validity and applicability of western guidelines in the Indian setting is not known. The aim of our study was to explore microbial prevalence and resistance patterns in a tertiary care Intensive Care Unit (ICU) in India and to determine whether western guidelines are still … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 28 Apr 2013 · 7,948 accessesView PDFCite