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200 articles for “Protein Level”
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Research ArticleOpen accessAll words, across the recordThe Use of α-MF Signal Peptide Without Spacer for Producing Insulin Aspart Precursor in Pichia pastoris KM71Popi Asri Kurniatin, Fifi Fitriyah Masduki, Neni Nurainy et al.A spacer peptide (Glu-Ala repeats) connects N-terminal of a polypeptide precursor to the signal peptide of α-mating factor (α-MF) from Saccharomyces cerevisiae. During the polypeptide precursor secretion, the signal peptide will be first cleaved by signal peptidase in the endoplasmic reticulum, followed by Kex2 endopeptidase and finally the spacer peptide is removed by dipeptidyl aminopeptidase in the Golgi apparatus. In … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 31 Oct 2019 · 9,034 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordExpression of Metallothionein-Like Protein 2B Gene Induced by Different Concentrations of Copper in White Spruce (Picea glauca)Megan McKergow, Kabwe NkongoloThe alterations to the expressions of metal transporter genes can induce metal ion uptake to maintain cell homeostasis when metal concentrations are low. Metallothioneins (MTs) are a class of low molecular mass (4-8 kDa), cysteine (Cys)-rich proteins that can bind metals via the thiol groups of their Cys residues. Studies on MT gene expressions in higher plants, such as conifers, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 25 Dec 2022 · 5,124 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordEffects of Dietary Supplementation with Pumpkin oil (Cucurbita pepo) on Performance and Blood Fat of Broiler Chickens during Finisher PeriodHosna Hajati, Ahmad Hasanabadi, Park W. WaldroupProblem statement: Using most of antibiotic growth promoters as feed additives has been banned by the European Union due to cross-resistance against pathogens and residues in tissues; and scientists search for alternatives to antibiotics, two days. In this view, medicinal plants and essential oils extracted are becoming more important due to their antimicrobial and stimulating effects on animal digestive systems. … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 26 Apr 2011 · 9,729 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordA Review: Microbiological, Physicochemical and Health Impact of High Level of Biogenic Amines in Fish SauceMuhammad Zukhrufuz Zaman, A. S. Abdulamir, Fatimah Abu Bakar et al.Problem statement: Biogenic amines are basic nitrogenous compounds present in a wide variety of foods and beverages. Their formations were mainly due to the amino acids decarboxylase activity of certain microorganisms. Excessive intake of biogenic amines could induce many undesirable physiological effects determined by their psychoactive and vasoactive action. Fish sauce which is considered as a good source of dietary … …American Journal of Applied Sciences, Vol. 6, Issue 6 · 30 Jun 2009 · 8,920 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordBiomedicine and Informatics Model of Alzheimer's DiseaseKang Cheng, Chang-Hua ZouIn a perspective of biomedicine and informatics, the mechanism of Alzheimer's, senile amnesia, or other aging-associated and cognitive impairment related diseases involve four important informative processing procedures: propagation, consolidation, retrieval and cognition, In this study, we systematically model the four procedures based on published experimental data. When modeling the propagation, we develop an equivalent circuit of biological membrane to describe … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 28 May 2007 · 6,828 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordLead Phytotoxicity Induced Changes in Biochemical Markers in Germination and Seedlings in Durum Wheat Triticum durum Desf. Cv.Vitron and GtaSoraya Slimani, Mokhtar Boudelaa, Saddek Abdelmadjid et al.Among the heavy metals most commonly found on land, lead is a strongly represented pollutant in soil and sediments. It is easily absorbed and accumulated in different parts of plants. On the macroscopic scale, lead causes unfavorable effects on plants. First and in the event of excess, it may exert toxicity affecting several stages of germination development in leaf formation … …American Journal of Environmental Sciences, Vol. 13, Issue 4 · 6 Sep 2017 · 7,482 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordEffect of Intraperitoneally Injection of Different Doses of Lovastatin on Pain and Inflammatory Response Induced by Formalin in MiceKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methyl Glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality. Their lipid-lowering actions are by reversible and competitive inhibition of the enzyme HMG-CoA reductase, a precursor of cholesterol. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels, such as … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,685 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordEffects of ced-9 dsRNA on Caenorhabditis elegans and Meloidogyne incognitaRobert T. Gaeta, Abdellatif Bahaji, Glenda W. Polack, Alejandro Calderón-UrreaAbstract: Problem Statement: In metazoans Programmed Cell Death (PCD) is essential for proper development. Suppression of PCD is needed to guarantee cell survival and in the nematode Caenorhabditis elegans the regulation of PCD is accomplished by the function of the ced-9 gene. Approach: In this work the use of double stranded RNA (dsRNA) to knock-down ced-9 gene function was tested … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 1 · 15 Dec 2010 · 9,456 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordOxidative Stress in Autism: Elevated Cerebellar 3-nitrotyrosine LevelsElizabeth M. Sajdel-Sulkowska, Boguslaw Lipinski, Herb Windom et al.It has been suggested that oxidative stress and/or mercury compounds play an important role in the pathophysiology of autism. This study compared for the first time the cerebellar levels of the oxidative stress marker 3-nitrotyrosine (3-NT), mercury (Hg) and the antioxidant selenium (Se) levels between control and autistic subjects. Tissue homogenates were prepared in the presence of protease inhibitors from … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 17,134 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordAccumulation of Cholesterol Esters in ex vivo Lymphocytes from Scrapie-susceptible Sheep and in Scrapie-infected Mouse Neuroblastoma Cell LinesAlessandra Pani, Claudia Norfo, Claudia Abete et al.Our studies on the role of cholesterol homeostasis in the pathogenesis of scrapie in sheep, revealed abnormal accumulation of cholesterol esters in brains and in ex vivo skin fibroblasts from genetically scrapie-susceptible, as compared to sheep with resistant genotype. We now report that PBMCs isolated from scrapie-susceptible sheep, as well as mouse neuroblastoma cell lines persistently infected with two different … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,960 accessesView PDFCite