Review ArticleOpen accessIn the abstractThe Effect of Main Heat Shock Proteins on AtherosclerosisAnastasia Vladimirovna Poznyak, Alexey V. Churov et al.Atherosclerosis is a multifaceted disease characterized by complex pathogenesis involving diverse mechanisms. In recent years, the autoimmune nature of atherosclerosis has gained significant attention, emphasizing the indispensable role of the immune system in its initiation and progression. Heat Shock Proteins (HSPs) are vital for cellular functionality, facilitating cellular adaptation to environmental changes and survival under adverse conditions. Notably, various HSP … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 3 Oct 2024 · 4,354 accessesView PDFCite
Research ArticleOpen accessIn the abstractProbiotics in Industrial Poultry FarmingOksana Smolovskaya, Vladimir Pleshkov, Tatiana Zubova, Larisa BorminaIn the conditions of industrial production, the problem of growing poultry with increased resistance to various diseases is relevant because the birds are exposed to various stress conditions. Traditionally, disease prevention is carried out through the use of vaccines, chemical pharmaceuticals, and antibiotics. The global use of therapeutic drugs contributes to the emergence of resistant strains of microorganisms and a … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 1 · 9 Jan 2023 · 6,174 accessesView PDFCite
Research ArticleOpen accessIn the abstractPurification, Structural Characterization and Anti-Aging and Stress Activities of Cordyceps Mycelium Polysaccharides from Paecilomyces HepialiXiaokang Hu, Huixiu Ma, Guicai Chen et al.This study identified and characterized the bioactive polysaccharide components from Cordyceps mycelium powder (CMP) derived from Paecilomyces hepiali, evaluating their anti-aging and stress-protective activities. Initial screening using Drosophila melanogaster revealed that crude Cordyceps polysaccharides (CCP) exhibited comparable effects to CMP and Cordyceps aqueous extracts (CAE) on natural lifespan and UV stress resistance, suggesting CCP as the primary bioactive component. CCP … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 16 Feb 2026 · 1,698 accessesView PDFCite
Research ArticleOpen accessIn the abstractNew Bivariate Exponentiated Modified Weibull DistributionAbdelfattah Mustafa, Mohamed A.W. MahmoudThe new modified Weibull distribution named exponentiated modified Weibull distribution introduced by many authors. In this study, we define and study a bivariate modified Weibull distribution. Some joint probability functions and conditional probability density function are obtained. Also, joint survival function is expressed in compact form. Several statistical properties of this distribution are discussed. In the area of stress-strength models, … …Journal of Mathematics and Statistics, Vol. 13, Issue 4 · 31 Oct 2017 · 7,000 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
Research ArticleOpen accessIn the abstractA New Bivariate Distribution with Generalized Quadratic Hazard Rate MarginalsAbdelfattah MustafaRecently, Sarhan (2009) introduced a new distribution named generalized quadratic hazard rate distribution. In this study, we define a bivariate Generalized Quadratic Hazard Rate Distribution (BGQHRD). The joint cumulative distribution function and joint survival function are derived in compact forms. Several properties of BGQFRD have been discussed. The conditional probability density function, rth moments and joint and marginal moment generating … …Journal of Mathematics and Statistics, Vol. 12, Issue 4 · 3 Nov 2016 · 6,749 accessesView PDFCite
EditorialOpen accessIn the abstractThe Food Additives Nitrite and Nitrate and Microbiological Safety of Food ProductsStefanie Müller-Herbst, Anna Mühlig, Jan Kabisch et al.In Germany, raw sausages are typically produced according to a technology referred to as hurdle technology (Leistner, 2000). The combination of several stressful conditions should successfully inhibit growth and survival of pathogenic bacteria, which can be regularly found in raw pork or beef material (Mataragas et al., 2008; Rhoades et al., 2009). Hurdles applied during raw sausage fermentation are the … …Current Research in Microbiology, Vol. 6, Issue 1 · 29 Jun 2015 · 10,378 accessesView PDFCite
Research ArticleOpen accessIn the abstractCOX’S PROPORTIONAL HAZARD MODEL AND CONSTRUCTION OF LIFE TABLE FOR UNDER-FIVESalam Shantikumar SinghA primary data of 836 eligible women in the age group of 15-49 years is used to determine the causal effects of covariates on under-five mortality. The eight covariates viz., Number of family Members (NHM), Type of Toilet Facility (TTF), Total Children ever Born (TCB), Parity (PAR), Duration of Breastfeeding (DBF), use Contraceptive (CMT), DPT and Ideal Number of Girl … …Current Research in Biostatistics, Vol. 4, Issue 1 · 18 Jul 2014 · 8,266 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Development of Parameter Estimation on Hazard Rate of Trivariate Weibull DistributionIrfan Wahyudi, Purhadi, Irhamah, SutiknoIn this study, the interrelation concepts of trivariate distribution function, trivariate survival function, trivariate probability density function and trivariate hazard rate function of trivariate Weibull distribution are presented. The goal of this contribution is to estimate the trivariate Weibull hazard rate parameters. To reach this goal, we will use an analitical approach in estimating called the Maximum Likelihood Estimation (MLE) … …Current Research in Biostatistics, Vol. 2, Issue 2 · 11 Aug 2012 · 8,923 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Dietary Kaempferia parviflora on Ischemic Brain Injury in the ratWathita Phachonpai, Sinthuporn Maharun, Supaporn Muchimapura et al.Problem statement: Stroke often causes irreversible neuronal damage and related behavioral deficits. The lack of effective and widely applicable pharmacological treatments for ischemic stroke patients may explain a growing interest in traditional plant medicines. We investigated the ability of consuming Kaempferia parviflora extract, a Thai medicinal plant reputed for neuroprotective effects against brain damage, reduced infarct volume and improve neurological … …OnLine Journal of Biological Sciences, Vol. 12, Issue 1 · 20 Mar 2012 · 9,088 accessesView PDFCite