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108 results for “risk function”
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Literature ReviewOpen accessIn the abstractMitochondrial Dysfunction Model in the Pathogenesis of Inflammatory Response Development in ObesityAlexander Blagov, Varvara Orekhova et al.Obesity is one of the growing problems of modern society. Although currently used methods of treating obesity, including diet, exercise, and drug therapy, have shown their applicability to more effectively combat obesity, an understanding of the pathogenesis of this disease is required. One of the insufficiently studied factors in the pathogenesis of obesity is the development of mitochondrial dysfunction understanding … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 19 Nov 2023 · 4,933 accessesView PDFCite
Research ArticleOpen accessIn the abstractPredictive Analysis of BMI and Liver Size on Kidney Function in Young Mexican American PopulationOrlando Patricio, Rohitha Goonatilake, Fernando G. Quintana et al.This study aimed todetermine the probability of fatty liver, hepatomegaly, and liver size ≥2SDwith age in each category of BMI percentile. It also aimed to investigate therelationship between GFR, BMI percentile, liver size, Blood Pressure (BP), andright kidney volume among overweight and obese boys and girls and to identifythe predictors of GFR. 763 records of boys and girls visiting a … …Journal of Mathematics and Statistics, Vol. 18, Issue 1 · 9 Sep 2022 · 5,540 accessesView PDFCite
Research ArticleOpen accessIn the abstractClimate-Driven Productivity Responses and Implications for Genetic Adaptation and Breeding of Boreal Trees in KazakhstanZhadyra Baigazakova, Kuralay Mazarzhanova, Asset Satayev et al.Kazakhstan’s boreal and forest-steppe forests form the southern ecotonal edge of the West Siberian taiga, where relatively small changes in heat and moisture can trigger disproportionate impacts on tree growth, mortality, and regeneration. Although forests cover only ~4% of Kazakhstan, they provide critical ecosystem services: stabilizing hydrological regimes, buffering microclimates, protecting agricultural lands from wind and water erosion, and supporting … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 10 Aug 2026 · 709 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetecting Novelty in Indonesian Research Grant Proposals Using Machine Learning and Natural Language ProcessingWalanstar Alimcan Sitorus, Evaristus Didik MadyatmadjaAssessing the novelty of research proposals represents a critical challenge in large-scale research grant management, particularly when the number of submitted proposals is substantial and topic diversity continues to increase. This study proposes an analytical approach to detect the novelty of Indonesian academic research proposal titles by leveraging semantic similarity based on Natural Language Processing (NLP). The CRISP-DM framework is … …Journal of Computer Science, Vol. 22, Issue 8 · 8 Aug 2026 · 1,067 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntegrated Monitoring of Endocrine-Disrupting Chemicals: Analytical Chemistry and Biological Assessment ApproachesChangjin Li, Jing Huo, Zijun Dou et al.Endocrine-Disrupting Chemicals (EDCs) in aquatic environments pose significant threats to ecosystems and human health. These compounds interfere with hormonal regulation at low concentrations and have non-monotonic dose-response relationships, posing challenges to conventional risk assessment. This review systematically compares current EDC monitoring methods, including instrumental chemical analysis and receptor-based biological detection systems, to evaluate sensitivity thresholds, sample throughput, and mechanistic selectivity … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 3 Jul 2026 · 1,081 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Vitamin D Deficiency on Cardio Metabolic Ageing in Middle Aged Adults in India: A Comparative AnalysisSumit Kumar, Adithi K, Shailaja S MoodithayaAdvancing age is accompanied by a gradual deterioration in physiological function, resulting in an increased risk of chronic diseases and early mortality. Growing evidence suggests that inadequate vitamin D status may be associated with unfavourable metabolic and cardiovascular alterations. Nevertheless, information regarding the association of vitamin D status with integrated cardio-metabolic biomarkers of ageing in middle-aged adults is currently limited. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 3 Sep 2026 · 732 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of CTLA-4 Inhibitor Combined with Chemotherapy on Immunoglobulin Levels and General Condition in Breast Cancer PatientsRuiguang CaiThis study conducted an evaluation of the CTLA-4 inhibitor ipilimumab plus standard chemotherapy on immunoglobulin levels, performance status, and Quality of Life (QoL) in patients with stage I-III Breast Cancer (BC) via a randomized controlled trial. 120 patients with stage I-III BC were randomly allocated to the experimental group (chemotherapy + ipilimumab) and the control group (chemotherapy), and the treatment … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 3 Jul 2026 · 1,115 accessesView PDFCite
Research ArticleOpen accessIn the abstractAI-Integrated Probabilistic Optimization for Inventory Control Under Stochastic DemandJanardan BeheraThe identification and operationalization of increasingly nonstationary and volatile demand patterns challenge the conduct of inventory management in contemporary supply chains. The classical models, especially EOQ and static policies, rest on the stability of demand assumptions, either deterministically or distributionally, and are hence less apt under real-world uncertainty. In view of these limitations, the present study puts forward an integrated … …Journal of Mathematics and Statistics, Vol. 22, Issue 1 · 6 May 2026 · 2,217 accessesView PDFCite
Research ArticleOpen accessIn the abstractRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDFCite
Review ArticleOpen accessIn the abstractBioactive Functional Foods for Cardiovascular DiseasesKiren Mustafa, Iqra Ajmal, Tahira Naz et al.Cardiovascular Disease (CVD) is a chronic pathological disorder regarded as a serious health concern round the globe. It is a multifactorial disease, with a range of various causative agents, among that dietary factor is considered the most important and may to a large degree determine CVD risk. Unfortunately, it has been less widely investigated. This review outlines the general aspects … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 17 Aug 2020 · 7,831 accessesView PDFCite