14 results for “proinflammatory cytokines”

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Research ArticleOpen accessIn the abstractExpression of Toll-like Receptors (TLRs) and Nucleotide-binding Oligomerization Domain (NODs) in murine peritoneal macrophages on in vitro treatment with Thymosin Î± 1Shikha Tarang, Ajit SodhiThymosin α 1 (Tα1) treatment of murine peritoneal macrophages in vitro induces the expression of TLRs and Nod2 proteins. Enhanced expressions of TLR2, -4, -5, -6, -7, -8, -9 and Nod2 were observed by RT-PCR and western blotting. Expression of downstream signaling molecules - MyD88, IRAK1, TRAF6, IRF3 were also up regulated on treatment with Tα1. It was also observed … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,150 accessesView PDF Cite

Research ArticleOpen accessIn the abstractInflammatory Cytokine Expression Patterns in Rat Skin Exposed to JP-8 Jet FuelRandle M. Gallucci, Bethany M. MickleOne of the main complaints of personnel exposed to JP-8 jet fuel is irritant dermatitis. The purpose of this investigation is to describe the JP-8 induced inflammatory cytokine response in skin over various periods of exposure. JP-8 jet fuel or acetone control (300 μL) was applied to the denuded skin of rats once a day for up to seven days. … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,042 accessesView PDF Cite

Research ArticleOpen accessIn the abstractBotulinum Toxin as a Novel Addition to Anti-Arthritis ArmamentariumHamid Namazi, Zahra MajdOsteoarthritis is the most common joint disease and is among the most frequent health problems for middle aged and older people. There is strong evidence that proinflammatory cytokines contribute to cartilage degradation in osteoarthritis. Interleukin-1 is the prototypical proinflammatory cytokine implicated in the pathogenesis of cartilage matrix degeneration. Results from studies in animal models provide stronger evidence implicating a role … …American Journal of Immunology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,775 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordPro-Inflammatory Cytokine (IL-1β and IL-6) Response in Goats Challenged with Corynebacterium pseudotuberculosis and its Immunogen Mycolic AcidsFaez Firdaus Jesse Abdullah, Odhah Mohd Naji, Mohd Azmi Mohd Lila et al.The causative agent of Caseous Lymphadenitis (CLA) is Corynebacterium pseudotuberculosis. A chronic disease of sheep and goats which is mainly characterized by suppurative abscesses in both superficial and visceral lymph nodes. There is paucity of information on the proinflammatory cytokine (IL-1β and IL-6) responses due to C. pseudotuberculosis and Mycolic Acid (MAs) inoculation in goats. Therefore, this study was conducted … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 1 · 16 Feb 2017 · 7,790 accessesView PDF Cite