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Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

12 articles for “p53 Gene”
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Research ArticleOpen accessIn the abstractRetinoids Chemosensitize Ovarian Cancer Cell Lines to Cisplatin Independent of Nuclear Receptors and p53Suresh Guruswamy, Doris M. BenbrookTreatment of ovarian cancer with cisplatin-based chemotherapy is highly toxic and is often followed by cancer recurrence. Repeated treatments with cisplatin frequently result in the development of resistance to this drug. Drugs with low toxicity that could enhance the tumor cell killing effects of cisplatin could potentially reduce the toxicity and enhance the efficacy of cisplatin. The mechanism of cell … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,958 accessesView PDFCite
Research ArticleOpen accessIn the abstractEssential Role of PKCδ in Apoptosis Induction of Mouse ThymocytesC. Lutz-Nicoladoni, T. Letschka, M. Leitges et al.The family of protein kinases C (PKCs) has been implicated in signal transmission leading to apoptosis induction and/or survival. These effects are cell type and tissue dependent. Numerous studies employing phorbol ester, a pleiotropic PKC activator, strongly implicated PKC in apoptosis induction of thymocytes. However, phorbol esters activate both, the conventional PKCs (PKCα, β, γ) as well as the novel … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 7,135 accessesView PDFCite