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38 articles for “oxidative system”
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InvestigationOpen accessIn the abstractRegularities of the Oxidative Stress Processes in Case of Bleedings from Acute and Chronic Ulcers of the Stomach and DuodenumEkaterina Vladimirovna Silina, Mukimdjon Ahmadzhonovich Sobirovz, Sergey Brankovich Bolevich, Victor Aleksandrovich StupinThe main aim of the study was to determine ways of improving the results of treating patients with ulcer bleeding of various nature and severity. It was provided by the system study of free radical processes and evaluation of the effectiveness of timely antioxidant therapy. Material and methods. The study included 153 patients aged 18-94 years with acute and chronic … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 4 May 2018 · 7,416 accessesView PDFCite
EditorialOpen accessIn the abstractGLUTATHIONE: A POSSIBLE LINK TO AUTOPHAGY IN SYSTEMIC LUPUS ERYTHEMATOSUSDilip Shah, Swapan K. NathIncreased free radical formation and altered redox state are of fundamental importance in the pathogenesis of autoimmune diseases including Systemic Lupus Erythematos (SLE). Free radicals are mainly derived from oxygen (Reactive Oxygen Species/ROS) and nitrogen (Reactive Nitrogen Species/RNS) at mitochondria, cellular membranes and the endoplasmic reticulum membrane as physiological responses to a variety of internal and external stress (Shah et … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 12,773 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetecting Patterns in 5’ Untranslated Regions of Genes Involved in the Regulation of Blood Pressure and Oxidative StressMaria Sanchez-Aguilar, Luz Ibarra-Lara, Beatriz Zamora-Lopez et al.Hypertension is a chronic physical condition with multifactorial causes. Although genetic factors have been associated to this pathological condition, characterization of the sequence patterns in the regulatory sites, for example, in 3’ or 5’ Untranslated Regions (UTR), remains to be explored. In particular, the 5’ UTR of genes associated with the regulation of blood pressure and oxidative stress are analyzed … …Current Research in Medicine, Vol. 4, Issue 2 · 27 Nov 2013 · 7,283 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Enicostemma littorale Blume Methanolic Extract on Gentamicin-Induced Nephrotoxicity in RatsNiraj Mukundray Bhatt, Kinjal Chauhan, Sharad Gupta et al.Problem statement: The Amino glycoside antibiotics cause drug induced nephrotoxicity at therapeutic doses and thus limits the use clinically. Oxidative stress is one of the main reasons for the development of nephrotoxicity. Approach: In light of this the aim of the present study was to investigate the role of mitochondrial as well as post-mitochondrial oxidative stress in the development of … …American Journal of Infectious Diseases, Vol. 7, Issue 4 · 30 Nov 2011 · 9,547 accessesView PDFCite
Research ArticleOpen accessIn the abstractCognitive-Enhancing and Antioxidant Activities of Quercetin Liposomes in Animal Model of Alzheimer's DiseaseTerdthai Tong-un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of Alzheimer’s Disease (AD). Antioxidant intake is beneficial to delay or inhibit the progression of this disease. Quercetin, a bioflavonoid in fruits and vegetables, has a powerful antioxidant activity both in vitro and in vivo. Claims that quercetin has many biological activities. However, quercetin is rapidly … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 31 Oct 2010 · 7,880 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect of Quercetin Encapsulated Liposomes: A Novel Therapeutic Strategy against Alzheimer’s DiseaseW. Phachonpai, J. Wattanathorn, S. Muchimapura et al.Problem statement: The prevalence of Alzheimer’s disease is increasing but the efficacy of treatment is still very limited due to various factors including the blood brain barrier. Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of disease. In addition the burden of blood brain barrier can be overcome by nasal administration and vesicle-carrier mediated delivery system. … …American Journal of Applied Sciences, Vol. 7, Issue 4 · 30 Apr 2010 · 9,449 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Potassium Levels on Antioxidant Enzymes and Malondialdehyde Content under Drought Stress in Sunflower (Helianthus annuus L.)H. Soleimanzadeh, D. Habibi, M.R. Ardakani et al.Problem Statement: Drought stress as a major adverse factor can lower leaf water potential, leading to reduced turgor and some other responses and ultimately lower crop productivity in arid and semi arid zones. Sunflower is one of the main oil seed crops in Iran, where drought stress is the most limiting factor. Drought stress tolerance requires the activation of complex … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 1 · 31 Mar 2010 · 10,779 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects Against Aluminum Chloride-Induced Normocytic Normocromic Anemia, Lipid Peroxidation and Oxidative Stress in Erythrocytes of White Albino RatsFahaid Al-HashemProblem statement: Aluminum (Al) is an indifferent element from a toxicological point of view. In recent years, however, Al has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problem in aluminum toxicity is anemia. The present study was carried out to determine the effectiveness of Camel’s milk in alleviating the toxicity of aluminum … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,021 accessesView PDFCite
Research ArticleOpen accessIn the abstractMitochondrial Energy-Deficient Endophenotype in AutismJ. Jay Gargus, Faiqa ImtiazWhile evidence points to a multigenic etiology of most autism, the pathophysiology of the disorder has yet to be defined and the underlying genes and biochemical pathways they subserve remain unknown. Autism is considered to be influenced by a combination of various genetic, environmental and immunological factors; more recently, evidence has suggested that increased vulnerability to oxidative stress may be … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 11,507 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormesis and Exercise: How the Cell Copes with Oxidative StressLi Li Ji, Zsolt Radak, Sataro GotoContraction-induced production of reactive oxygen and nitrogen species has been shown to cause oxidative stress to skeletal muscle, heart and other organs. As an adaptive response, muscle antioxidant defense systems are upregulated in response to exercise to restore intracellular prooxidantantioxidant homeostasis. Thus, both young and old animals and humans involved in regular exercise have shown reduced oxidative damage during acute … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,817 accessesView PDFCite