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16 results for “osteoarthritis”
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Research ArticleOpen accessIn the keywordsThe Effect of Bone Properties due to Skeletal Diseases on Stability of Cementless Hip StemsMohammed Rafiq Abdul Kadir, Nazri KamsahProblem statement: There are two types of implant fixation in hip joint replacement-cemented and cementless. The cemented types are, in general, more popular due to concerns of possible inability of cementless implants achieving maximum primary stability for bone integration. The concern is more significant in cases where there are major losses of cancellous bone stock and thinning of the trabeculae … …American Journal of Applied Sciences, Vol. 6, Issue 12 · 31 Dec 2009 · 7,169 accessesView PDFCite
Review ArticleOpen accessIn the abstractSIRT1 Controls Lipid Metabolism Under Physiological and Pathological Conditions: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Ludmila Viktorovna Nedosugova, Victoria Alexandrovna Khotina et al.This comprehensive review examines the multifaceted role of Sirtuin 1 (SIRT1) in cellular metabolism and energy regulation, with a particular focus on its involvement in lipid metabolism and glucose regulation. Additionally, SIRT1's impact on several pathologies, including osteoarthritis, diabetes, and cardiovascular disease, is explored. Notably, this review sheds light on the unique contribution of SIRT1 in the development and progression … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 7 Jun 2024 · 4,739 accessesView PDFCite
HypothesisOpen accessIn the abstractCJ-023,423 (Grapiprant) a Potential Novel Active Compound with Antihyperalgetic Properties for Veterinary PatientsMario GiorgiCompanion animals are now living longer and so are more commonly manifesting age- and pain-related disease. Nonsteroidal anti-inflammatory drugs are the most used drug in osteoarthritis and inflammatory pain of various aetiologies. Despite their safety profiles have been amended from the COX-non selective to the COX-2 selective inhibitor class, some adverse effects are still of concern especially in long term … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 14 May 2015 · 8,874 accessesView PDFCite
Research ArticleOpen accessIn the abstractPathomorphological Findings of White Line Disease with Digital and Inner Organ Infections in Culling Dairy CowsMohsen Nouri, Iradj Nowrouzian, Seyyed Hossein Marjanmehr et al.The aim of this study was to investigate pathomorphological findings of white line disease in culling lame cows, with special reference to the lesions and their distribution. The most prominent pathomorphologic findings of the claw with white line disease included extensor process entheseophyte (75.0%), flexor tuberisity entheseophyte (37.5%) and abaxial margin bone absorption (68.7%). Six out of the total of … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 30 Aug 2013 · 7,257 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Dietary Polydextrose on Feces Consistency and Macronutrient Digestibility in Healthy DogsK. Vasupen, C. Yuangklang, A. C. Beynen, A. W.C. EinerhandProblem statement: There is evidence that the addition of 3% STA-LITE® polydextrose to a dry food reduces clinical signs of osteoarthritis in dogs. For the application of polydextrose as functional ingredient of dog foods, information as to its impact on the acceptance of food, feces consistency, fecal odor and digestibility of macronutrients and minerals is required. Approach: A feeding experiment … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 3 · 5 Oct 2011 · 8,520 accessesView PDFCite
Research ArticleOpen accessIn the abstractBotulinum Toxin as a Novel Addition to Anti-Arthritis ArmamentariumHamid Namazi, Zahra MajdOsteoarthritis is the most common joint disease and is among the most frequent health problems for middle aged and older people. There is strong evidence that proinflammatory cytokines contribute to cartilage degradation in osteoarthritis. Interleukin-1 is the prototypical proinflammatory cytokine implicated in the pathogenesis of cartilage matrix degeneration. Results from studies in animal models provide stronger evidence implicating a role … …American Journal of Immunology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,775 accessesView PDFCite