13 results for “neurodegeneration”

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Research ArticleOpen accessIn the abstractNeuroprotective Effect against Alzheimer's Disease of Porcine Brain ExtractWipawee Thukham-Mee, Jintanaporn Wattanathorn, Supaporn Muchimapura, Chuleratana BunchonglikitkulProblem statement: Despite the increasing importance of Alzheimer’s disease, no effective therapeutic strategy is available. Therefore, neuroprotective strategy is still required. Recent findings show that numerous substances possessing antioxidant can improve neurodegeneration and memory impairment. Based on the antioxidant effect and its reputation to serve as brain tonic in traditional folklore, we hypothesized that porcine brain extract could mitigate neurodegeneration … …American Journal of Applied Sciences, Vol. 9, Issue 5 · 5 Mar 2012 · 8,243 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNeuroprotective Effect of Quercetin Encapsulated Liposomes: A Novel Therapeutic Strategy against Alzheimer’s DiseaseW. Phachonpai, J. Wattanathorn, S. Muchimapura et al.Problem statement: The prevalence of Alzheimer’s disease is increasing but the efficacy of treatment is still very limited due to various factors including the blood brain barrier. Recent findings demonstrated the crucial role of oxidative stress on the pathophysiology of disease. In addition the burden of blood brain barrier can be overcome by nasal administration and vesicle-carrier mediated delivery system. … …American Journal of Applied Sciences, Vol. 7, Issue 4 · 30 Apr 2010 · 9,449 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNeuropsychological Consequences of HIV and Drug AuseArun Venkatesan, Ola Selnes, Valerie Wojna et al.Accurate assessment of the functional consequences of human immunodeficiency virus (HIV) infection and drugs of abuse are critical as large populations are afflicted with both. Both are interdependent epidemics with important socioeconomic consequences. Experimental studies in animal models and in vitro clearly indicate that HIV and drugs of abuse cause increased neurodegeneration, glial cell activation and enhanced HIV replication. Nevertheless, … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,662 accessesView PDF Cite