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75 articles for “metabolites”
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Research ArticleOpen accessEvery word in the titleSecondary Metabolites in Essential Oil of Achillea millefolium (L.) Growing Wild in East Part of KosovaArben I. Haziri, Nevzat Aliaga, Murtezan Ismaili et al.Problem statement: Chemical composition of essential oil of Achillea millefolium (L.), originated from east part of Kosova, was investigated. Approach: The chemical profile of the essential oil was evaluated by GC and GC-MS. Results: Analysis of the oil resulted in the identification of 33 peaks, representing 81.4% of the oil. The main compounds of Achillea millefolium (L.) from east region … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 1 · 31 Mar 2010 · 8,674 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMolecular Identification and Antioxidant Profiling of Penicillium heteringtonii EUA-017 from Mangrove (Avicennia alba) in West Sumatra, IndonesiaAnthoni Agustien, Djong Hon Tjong, Yetria Rilda et al.Mangrove ecosystems harbor diverse endophytic fungi that produce bioactive secondary metabolites with potential antioxidant activities. This study aimed to identify an endophytic fungal isolate (EUA-017) from Avicennia alba mangroves in West Sumatra, Indonesia, and characterize its antioxidant metabolites. Molecular identification was performed using internal transcribed spacer (ITS) region sequencing. Secondary metabolites from ethyl acetate extracts were characterized using Fourier-transform infrared … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 25 Mar 2026 · 1,410 accessesView PDFCite
Review ArticleOpen accessIn the keywordsBio-Exploration of Plant Growth-Promoting Fungus Trichoderma as a Potent Candidate for Plant Disease Management: An OverviewMd. Tanbir Rubayet, Md. Motaher HossainChemical pesticides are widely used to control plant diseases, but their widespread use can have a detrimental impact on the environment and human health. This has led researchers and growers to seek out alternative solutions. One promising approach is the use of the Plant Growth-Promoting Fungus (PGPF) Trichoderma spp. as a biological control agent. This method is effective, cost-efficient, and … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 21 Sep 2024 · 5,107 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCopper (I)-Nicotinate Promotes Gene Expression of CYPs that Produce M1 and Q1 in Aflatoxicosed RatsMohammed Salah, Laila Mostafa, Tahia H. Saleem et al.Aflatoxin-contaminated food poses a serious risk to both human and animal health. Copper (1)-nicotinate (Cu+-nicotinate) complex potentiated the prophylactic effect against chronic aflatoxicosis in the experimental animals through the synthesis of less toxic metabolites M1 and Q1 which are easily excreted in urine. To investigate the action of the safety Cu+-nicotinate complex on gene expression of Cytochrome 450 (CYP450) system, … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 28 Jan 2020 · 8,152 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Phenolic Ester of O-Desmethylvenlafaxine (ODV) Improves Uptake of ODV into the BrainYang Zhang, Zhichao Yang, Sen Zhao, Hongli ZhouIn this study, the in vitro stabilities of a promising O-Desmethylvenlafaxine (ODV) phenolic ester prodrug O-19 in aqueous solution, rat whole blood and rat liver microsomes were investigated. In addition, the in vivo drug metabolites were determined using LC-TOFMS-IDA-MS/MS. O-19 exhibits high stabilities at any pH encountered in the gastrointestinal tract, its half live (t1/2) spans the range 5.0±0.18 d … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 4 · 11 Dec 2016 · 7,157 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBioautography Guided Identification of Anticandidal Compounds from A. terreus st. 1B. K. Nagaraja, R. Sripathy, C. N. Ramchand, M. SundararamanProblem statement: Saprophytic and soil inhabiting microorganisms are prolific producers of secondary metabolites with wide range of structural and functional diversity. The objective of the current study was to screen and evaluate the anti-candidal properties of soil inhabiting fungi. Approach: Preliminary dual culture assay and bioautography was used to screen the fungi with potential anti-fungal activity and direct detection of … …American Journal of Infectious Diseases, Vol. 7, Issue 4 · 1 Dec 2011 · 7,629 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn Vitro Metabolism Studies of Polybrominated Diphenyl Ethers Using Rat and Human Liver MicrosomesShun Wen Cheng, Kathleen Randall, Anne T. KotchevarA number of studies have recently reported the bioaccumulation of the commonly used fire retardants, Polybrominated Diphenyl Ethers (PBDEs), in humans and wildlife. Exposure of animals to PBDEs has been shown to result in developmental neurological, reproductive abnormalities and the disruption of endocrine function. Thyroid hormone equilibria was also shown to be altered by PBDE exposure. There is evidence that … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 6,998 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Effect of the Saccharomyces Boulardii Supplement in Combined Feed on the Health, Growth, and Fecal Microbiota of Growing CalvesDulat Zhalelov, Serkan Ozkaya, Mehmet Gündoğdu et al.The aim of this study was to study the effect of a specific strain of yeast, Saccharomyces cerevisiae boulardii T8-3C (SCB), on the growth, health, and bacterial profile of calves' feces. A total of 12 animals were included in the experiment on a commercial calf farm for a total of 90 days. The calves were fed hay and alfalfa twice … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 27 Nov 2025 · 2,309 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMetabolite Profiles of Arsenic Tolerant Plants Regenerated from Stem Calli of Andrographis paniculata (Burm.f.) Nees using HPLC and 1D 1H NMRJ. Vijayakumar, P. Ponmanickam, P. Samuel et al.In vitro culture provide a suitable condition for regeneration of arsenic tolerant plants from stem calli of Andrographis paniculata (Burm.f.) Nees. The regenerated plants could be valuable material applicable to soil remediation. In vitro culture of stem explants on MS basal salts, 3.0% sucrose, 0.8% agar medium fortified with various concentrations of As2O3 (0.0-9.0 µM) along with NAA (3.5 mg … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 27 Oct 2017 · 7,865 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPhytochemical Screening of Methanolic Extracts of Different Parts of Rudraksh Plant (Elaeocarpus Ganitrus)Pratyush Kumar DasSince time immemorial plants have played a vital role in the field of health care and medicines. There are many plants with high medicinal values among which Elaeocarpus ganitrus (Rudraksh) holds utmost importance, both scientifically as well as spiritually. The different parts of a rudraksh tree have high concentrations of important phytochemical constituents thus adding to its medicinal value. This … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 22 Jun 2015 · 7,548 accessesView PDFCite