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Research ArticleOpen accessEvery word in the titleTelomere Length Measurement by Quantitative Real-time PCR: A Molecular Marker for Human Age PredictionNaglaa F. Alhusseini, Abdelmonem G. MadbolyThe fact that telomere shortening occurs with aging leads to the hypothesis that a correlation could be made between Telomere Length (TL) and suspect age. This study aimed to assess if TL can be used as an investigational tool to predict human age through developing a formula based on this correlation with accuracy suitable to be applied in forensic practice. … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 1 · 24 Mar 2016 · 8,004 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlesuPAR as an Inflammatory and Preclinical Atherosclerotic Marker in Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Neelam Manjunath Pawar et al.The mechanistic link between inflammation and atherosclerosis highlights the critical role of immune modulation in cardiovascular disease. The soluble urokinase plasminogen activator receptor (suPAR), an immune-derived factor, has recently emerged as a non-specific inflammatory marker across chronic diseases and infections. All cells within the atherosclerotic arterial wall can express uPAR and release urokinase, which plays a key role in the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 30 Mar 2026 · 1,122 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDecoding Lung Cancer: PLAU as a Critical Driver and Diagnostic MarkerStanley Cho, Min Gyeong KimLung cancer remains a leading cause of cancer-related mortality, and understanding its underlying molecular mechanisms is critical for developing targeted therapies. We developed a novel tool called the Transcriptome-TCGA Integration (TTI), which combines in vitro transcriptome data with clinical datasets from the Cancer Genome Atlas (TCGA). TTI allows for the identification of key genes and pathways involved in lung cancer, … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,424 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMMP-9 is a Potential Prognostic Marker of Left Ventricular Remodeling in Patients with Coronary Artery DiseaseMikhail Aleksandrovich Popov, Anastasia Vladimirovna Poznyak, Dmitry Valerievich Shumakov et al.Matrix Metalloproteinase-9 (MMP-9) emerges as a promising prognostic marker for assessing left ventricular remodeling in patients with coronary artery disease, particularly in the context of Ischemic Heart Disease (IHD) complicated by left ventricular aneurysm. In this study, we conducted two parallel investigations to explore the prognostic significance of MMP-9 in patients with multivessel coronary artery disease undergoing left ventricular reconstruction … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 11 Jul 2024 · 4,310 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEchocardiographic Pulmonary to Left Atrial Ratio in Dogs (ePLAR): A Differential Marker of Pre- and Postcapillary Pulmonary HypertensionDmitrij Oleynikov, Ma YiPulmonary Hypertension (PH) in dogs is a complicated syndrome that could be primary, due to idiopathic or genetic causes, or secondary due to pulmonary disease, pulmonary thromboembolism, heartworm disease, heart failure. Due to the inability of the routine use of right heart catheterization in veterinary patients, there is a lack of differential criteria between PH forms. This study was performed … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 1 · 17 Feb 2022 · 6,791 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNCCRP-1 Might Not be a Marker of so Called NCC Cells in Common Carp (Cyprinus carpio) LeukocytesMazal Shimon-Hophy, Avi Jacob, Ramy R. AvtalionThe purpose of this study was to verify whether NCCRP-1 is a marker of a unique type of cells in teleost, so-called NCC, or an ubiquitin, like in cytotoxic cells. Therefore, common carp peripheral blood leukocytes were isolated and tested for the binding of fluorescent NCCRP-1 antibody to stained MAIT, γδ T and T cells following stress treatments. The results … …American Journal of Immunology, Vol. 16, Issue 1 · 26 Mar 2020 · 7,755 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffectiveness of the Use of Genetic Markers of Meat Productivity in the Kazakh White-Headed Breed Identified Using Genome-Wide Association StudyIndira Beishova, Askar Nametov, Alzhan Shamshidin et al.The study aimed to determine the effectiveness of the use of genetic markers in cattle of the Kazakh white-headed breed identified using a genome-wide association study. The object of the study was the livestock of 790 Kazakh white-headed bulls bred in breeding farms of the Republic of Kazakhstan. The study adheres to rigorous ethical standards, with all procedures approved by … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 25 Jun 2024 · 5,023 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTHYROID HORMONES (T3 AND T4) AS A MARKER OF UTERINE CANCER RISK FACTOR AFTER MENOPAUSEZena A.M. Al-JawadiDue to limited available information of the correlation between T3 and T4 on uterine cancer. This study focused on the following: Possibility of T3 and T4 as a marker of uterine cancer by studying the relationship between T3 and T4 and uterine cancer through a hormonal parameters. The study included collection of samples attending the Hospitals in Mosul, divided to … …American Journal of Applied Sciences, Vol. 11, Issue 5 · 15 Mar 2014 · 6,932 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOSTEOPOROSIS AS A NOVEL MARKER OF UTERINE CANCER RISK FACTORZena Abdul Monim Al-Jawadi, Zainab Mahfoth Al-noaymyDue to limited available information on the occurrence and treatment of uterine cancer, health institutions in major countries trend to study some factors and diseases that may relation or plays as predisposing factors of the occurrence of uterine cancer and the lack of previous studies on the impact of osteoporosis on the incidence of uterine cancer and the rapid spread … …American Journal of Applied Sciences, Vol. 11, Issue 1 · 7 Dec 2013 · 6,875 accessesView PDFCite