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21 results for “mammalian cells”
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Research ArticleOpen accessIn the abstractINDUCED PLURIPOTENT STEM CELLS AND THEIR IMPLICATION FOR BIOMEDICAL SCIENCESMaria Csobonyeiova, Stefan Polak, Lubos DanisovicThe groundbreaking discovery, that somatic mammalian cells can be epigenetically reprogrammed to a pluripotent state through the exogenous expression of the transcription factors Oct4, Sox2, Klf4 and c-myc, has yielded a new cell type for potential application in regenerative medicine, the induced Pluripotent Stem Cells (iPSCs). Since the first demonstration of creating iPSCs in 2006 great efforts have been made … …OnLine Journal of Biological Sciences, Vol. 13, Issue 4 · 3 Oct 2013 · 7,027 accessesView PDFCite
Research ArticleOpen accessIn the abstractPolymorphisms in the 5’ Flanking Region and First Exon of Insulin-Like Growth Factor 1 Gene in Southern Populations of BuffaloSaber Khederzadeh, Ahmad YazdanpanahThe Insulin-like Growth Factor 1 (IGF-1) system plays a critical endocrine role controlling nutrient metabolism in animals and it is a group of structurally-related polypeptides that regulate the growth of many types of mammalian cells. In liver, IGF-1 is dynamically regulated by lactation and energy balance. Less is known about the regulation of IGF-1 and IGF-binding protein mRNA in reproductive … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 6,849 accessesView PDFCite
Research ArticleOpen accessIn the abstractPolymorphism of Insulin-Like Growth Factor 1 Gene in Najdi Cattle PopulationsAhmad Yazdanpanah, Khalil Mirzadeh, Morteza Mamouei et al.The Insulin-like Growth Factor 1 (IGF-1) system plays a critical endocrine role controlling nutrient metabolism in dairy cattle and it is a group of structurally-related polypeptides that regulate the growth of many types of mammalian cells. In liver, IGF-1 is dynamically regulated by lactation and energy balance. Less is known about the regulation of IGF-1 and IGF-binding protein mRNA in … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,157 accessesView PDFCite
Research ArticleOpen accessIn the abstractStem Cells in Traumatic Brain InjurySamuel Dobrowolski, Guilherme LepskiTraumatic Brain Injury (TBI) is a devastating clinical condition that often causes permanent incapacity, especially in the younger population. The clinical relevant of TBI justifies the scientific interest in the pathophysiology of TBI, as well as in protective effects and development of treatment options. Stem cells have the ability to induce neuroprotection and neural repair inflammatory suppression, causing tissue reconstruction … …Neuroscience International, Vol. 4, Issue 1 · 12 Apr 2013 · 7,568 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Immunomodulatory Effect: Selection of the Correct Targets for Immunostimulation StudySwee Keong Yeap, Mashitoh Binti Abd Rahman, Noorjahan Banu Alitheen et al.Problem statement: Numerous plants or remedies that are traditionally used for various diseases had been claimed to maintain general good health, particularly the immune system. With the advanced understanding on immunology and ethnopharmacology, study on the interaction of this herb with the immune system is critical to understand the safety and its efficacy as a potent immunomodulatory agent. Approach: Selecting … …American Journal of Immunology, Vol. 7, Issue 2 · 4 Nov 2011 · 10,742 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification the Specific Relationships among Physical Parameters which Use to Quantify Inactivation Effect of Charged Particles at Low DosesAbubaker Ali Yousif, Ismail Bin Bahari, Muhamad Samudi YasirProblem statement: The relationships among physical qualities parameters which are characterized charged particles are not extensively determined for all types of ionizing radiations; the specific physical parameters that are also qualified to quantify the radiation effects of charged particles have been investigated. Approach: Secondary data of charged particles which are used to irradiate mammalian cells in vitro has been employed … …Physics International, Vol. 1, Issue 2 · 31 Dec 2010 · 6,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractHistological Study of Cervix Uteri in Caspian Miniature HorseM. Rezaian, S. HamediProblem statement: Uterine cervix which separates the uterus from the vagina, shows remarkable anatomical and histological differences among mammalian species. Since no cleared observations have been found in regards with the Caspian miniature horses’ cervix, the aim of the present study was to supplement this missing information which could be helpful for providing a stricter basis in detecting reproductive diseases … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 7,674 accessesView PDFCite
Research ArticleOpen accessIn the abstractCryptolepine Provokes Changes in the Expression of Cell Cycle Proteins in Growing CellsCharles Ansah, Nigel J. GooderhamProblem statement: Cryptolepine, the antimalarial plant alkaloid is cytotoxic to mammalian cells, but there is rather little understanding of the possible mechanisms involved in the cell-kill action of cryptolepine. Approach: We examined mammalian cells exposed to cryptolepine (0.5-5.0 μM) for effects on the cell cycle and associated alterations in the levels of major regulatory proteins using immunoblotting and flow cytometry. … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,400 accessesView PDFCite
Research ArticleOpen accessIn the abstractModification of Artificial Oliogosaccharides in Recombinant Escherichia coli CellsTomohisa Kato, Rie Mitsumori, Kenichi HatanakaArtificial oligosaccharides were modified using recombinant Escherichia coli cells that overexpress sialidase. Based on the principle of the saccharide primer method by using bacterial cells overexpressing enzymes related to oligosaccharide modification. Problem statement: It is very hard to obtain oligosaccharides, because they have complex and diverse structures with different linkage patterns and monosaccharide components. Approach: It had been known that … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 6,804 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordAnalysis of Nucleoli in Intact Lymphocytes in Different Mammalian Species and HybridsBaylar Iolchiev, Pavel Klenovitskiy, Vugar Bagirov et al.The purpose of this study was to develop methods for quantitative and qualitative assessment of the activity of the nucleolus using the color intensity of argyrophilic regions and to study the effect of the species feature on the quantitative and qualitative indicators of the nucleoli and nucleolus organizer regions. The experiment involved Ovis aries (n = 40), hybrids of domestic … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 24 Jan 2022 · 6,070 accessesView PDFCite